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Lightweight, Compact, Low-Cryogen, Head-Only 7T MRI for High Spatial Resolution Brain Imaging

Award Number: U01EB026976
ORGANIZATION: NATIONAL INSTITUTE Of BIOMEDICAL IMAGING & BIOENGINEERING
OPDIV: NIH
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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PROJECT SUMMARY/ABSTRACT An innovative head-only 7T MRI system that delivers spatial resolution that is difficult to achieve with today's whole-body 7T systems, and has the footprint and weight of a whole-body 3T scanner is proposed. This new im- aging system combines a high-performance asymmetrical head gradient that delivers 130 mT/m and 900 T/m/s performance in an actively shielded, low-cryogen, lightweight head-only 7T magnet. The multi-disciplinary group from GE Global Research, the University of California-San Francisco, and the Mayo Clinic will deliver this unique imaging tool to better understand and discover new brain processes. The high gradient amplitude and high slew rate will be leveraged to develop applications for high spatial resolution imaging of brain microstruc- ture, functional brain activation, arterial and venous vasculature, and to profile brain metabolites that are criti- cal to neurotransmission and brain function, especially in regions of the brain that have previously eluded re- searchers due to resolution and susceptibility limitations. The proposed head-only 7T MR system is dramatically smaller and 70% lighter weight compared to other ultra-high field MRI systems. This enables a high-resolution brain research platform to be installed in locations that otherwise could not support a conventional ultra-high field MRI system, providing greater access to this technology to increase knowledge generation of how the brain works.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2024 ( Subtotal = $0 )
2024	2022	GENERAL ELECTRIC COMPANY	1 RESEARCH CIR	NISKAYUNA	NY	12309	SCHENECTADY	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	000	5	2/6/2024	NON-COMPETING CONTINUATION	-$4
2024	2022	GE MEDICAL SYSTEMS INFORMATION TECHNOLOGIES, INC.	1 RESEARCH CIR BLDG K-1	NISKAYUNA	NY	12309	SCHENECTADY	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	001	6	3/8/2024	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$4
														Subtotal = $0

Issue Date FY: 2023 ( Subtotal = $0 )
2023	2022	GENERAL ELECTRIC COMPANY	1 RESEARCH CIR	NISKAYUNA	NY	12309	SCHENECTADY	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	000	5	9/14/2023	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2022 ( Subtotal = $1,545,105 )
2022	2022	GENERAL ELECTRIC COMPANY	1 RESEARCH CIR	NISKAYUNA	NY	12309	SCHENECTADY	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	000	5	6/27/2022	NON-COMPETING CONTINUATION	$1,545,105
														Subtotal = $1,545,105

Issue Date FY: 2021 ( Subtotal = $1,708,241 )
2021	2021	GENERAL ELECTRIC COMPANY	1 RESEARCH CIR	NISKAYUNA	NY	12309	SCHENECTADY	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	000	4	8/23/2021	NON-COMPETING CONTINUATION	$1,708,241
														Subtotal = $1,708,241

Issue Date FY: 2020 ( Subtotal = $3,949,609 )
2020	2020	GENERAL ELECTRIC COMPANY	1 RESEARCH CIR	NISKAYUNA	NY	12309	SCHENECTADY	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	000	3	7/27/2020	NON-COMPETING CONTINUATION	$3,474,004
2020	2020	GENERAL ELECTRIC COMPANY	1 RESEARCH CIR	NISKAYUNA	NY	12309	SCHENECTADY	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	001	3	8/14/2020	SUPPLEMENT FOR EXPANSION	$475,605
														Subtotal = $3,949,609

Issue Date FY: 2019 ( Subtotal = $3,852,405 )
2019	2019	GENERAL ELECTRIC COMPANY	1 RESEARCH CIR	NISKAYUNA	NY	12309	SCHENECTADY	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	001	2	8/22/2019	NON-COMPETING CONTINUATION	$3,852,405
2019	2018	GENERAL ELECTRIC COMPANY	1 RESEARCH CIR	NISKAYUNA	NY	12309	SCHENECTADY	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	000	1	12/21/2018	NEW	$0
														Subtotal = $3,852,405

Issue Date FY: 2018 ( Subtotal = $2,870,452 )
2018	2018	GENERAL ELECTRIC COMPANY	1 RESEARCH CIR	NISKAYUNA	NY	12309	SCHENECTADY	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	000	1	9/22/2018	NEW	$2,870,452
														Subtotal = $2,870,452

Grand Total All Awards = $13,925,812

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Lightweight, Compact, Low-Cryogen, Head-Only 7T MRI for High Spatial Resolution Brain Imaging

Award Number: U01EB026976

ORGANIZATION: NATIONAL INSTITUTE Of BIOMEDICAL IMAGING & BIOENGINEERING

OPDIV: NIH

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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