Tuesday, November 28, 2023 11/28/2023

Continuation of the UIC Chronic Renal Insufficiency Cohort Clinical Center

Award Number: U01DK060980
ORGANIZATION: NATIONAL INSTITUTE OF DIABETES & DIGESTIVE & KIDNEY DISEASES
OPDIV: NIH
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

Group Awards By Issue Date FY or Funding FY:

View Award Abstract

From 2003 to 2008, the prospective Chronic Renal Insufficiency Cohort (CRIC) Study enrolled 3,939 adults with chronic kidney disease (CKD) to address overarching goals of identifying predictors of rapid progression of kidney disease and clarifying the relationship between kidney dysfunction and the risks of subclinical and clinical cardiovascular events, death, and resource utilization. During the last funding period (2013-2018), CRIC continued to follow the cohort and recruited an additional 1,465 individuals with milder CKD. The study has been successful in publishing over 150 articles, promoting young investigative careers, establishing an active ancillary study program, and fostering international collaborations. The next phase of the study, which extends follow-up through 2023, will afford a unique opportunity to focus on two content areas of particular importance to the understanding and, ultimately, the treatment of CKD: 1) the investigation of non-linear trajectories of renal function using in-home serum creatinine and urine protein testing systems, and 2) the identification of cardiovascular sub-phenotypes detected using ambulatory noninvasive biosensors. The study will evaluate these two novel measures as both exposures and outcomes. This application is submitted in response to RFA-DK-17-508, “Limited Competition: Continuation of the Chronic Renal Insufficiency Cohort (CRIC) Study (U01)” on behalf of the University of Illinois at Chicago (UIC) Clinical Center. During the first three phases of the CRIC Study, the UIC Clinical Center research team has been successful in terms of recruitment, retention, protocol implementation, data quality, and scientific productivity. Noteworthy achievements at UIC have included a strong focus on heath disparities in CKD, a significant number of UIC investigator-led publications, leadership on funded-ancillary studies (i.e., two R01s, two K23s, one K24, and four Diversity Supplements), and the promotion of new physician-scientists.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2024 ( Subtotal = $0 )
2024	2023	UNIVERSITY OF ILLINOIS	809 S MARSHFIELD AVE M/C 551	CHICAGO	IL	60612	COOK	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	001	23	10/31/2023	COMPETING CONTINUATION	$539,295
2024	2022	UNIVERSITY OF ILLINOIS	809 S MARSHFIELD AVE M/C 551	CHICAGO	IL	60612	COOK	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	22	10/31/2023	NON-COMPETING CONTINUATION	-$539,295


Issue Date FY: 2023 ( Subtotal = $299,631 )
2023	2023	UNIVERSITY OF ILLINOIS	809 S MARSHFIELD AVE M/C 551	CHICAGO	IL	60612	COOK	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	23	7/28/2023	COMPETING CONTINUATION	$299,631


Issue Date FY: 2022 ( Subtotal = $571,523 )
2022	2022	UNIVERSITY OF ILLINOIS	809 S MARSHFIELD RM 520	CHICAGO	IL	60612	COOK	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	001	22	7/21/2022	NON-COMPETING CONTINUATION	$571,523
2022	2021	UNIVERSITY OF ILLINOIS	809 S MARSHFIELD RM 520	CHICAGO	IL	60612	COOK	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	21	12/16/2021	NON-COMPETING CONTINUATION	$0


Issue Date FY: 2021 ( Subtotal = $592,065 )
2021	2021	UNIVERSITY OF ILLINOIS	809 S MARSHFIELD RM 520	CHICAGO	IL	60612	COOK	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	21	7/1/2021	NON-COMPETING CONTINUATION	$592,065


Issue Date FY: 2020 ( Subtotal = $592,065 )
2020	2020	UNIVERSITY OF ILLINOIS	809 S MARSHFIELD RM 520	CHICAGO	IL	60612	COOK	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	001	20	6/30/2020	NON-COMPETING CONTINUATION	$592,065
2020	2019	UNIVERSITY OF ILLINOIS	809 S MARSHFIELD RM 520	CHICAGO	IL	60612	COOK	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	19	3/3/2020	NON-COMPETING CONTINUATION	$0


Issue Date FY: 2019 ( Subtotal = $602,427 )
2019	2019	UNIVERSITY OF ILLINOIS	809 S MARSHFIELD RM 520	CHICAGO	IL	60612	COOK	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	001	19	7/16/2019	NON-COMPETING CONTINUATION	$602,427
2019	2017	UNIVERSITY OF ILLINOIS	809 S MARSHFIELD RM 520	CHICAGO	IL	60612	COOK	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	17	2/5/2019	NON-COMPETING CONTINUATION	$0


Issue Date FY: 2018 ( Subtotal = $613,095 )
2018	2018	UNIVERSITY OF ILLINOIS	809 S MARSHFIELD RM 520	CHICAGO	IL	60612	COOK	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	001	18	8/28/2018	COMPETING CONTINUATION	$613,095
2018	2017	UNIVERSITY OF ILLINOIS	809 S MARSHFIELD RM 520	CHICAGO	IL	60612	COOK	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	17	8/27/2018	NON-COMPETING CONTINUATION	$0


Issue Date FY: 2017 ( Subtotal = $635,000 )
2017	2017	UNIVERSITY OF ILLINOIS	809 S MARSHFIELD RM 520	CHICAGO	IL	60612	COOK	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	003	17	6/19/2017	NON-COMPETING CONTINUATION	$635,000
2017	2016	UNIVERSITY OF ILLINOIS	809 S MARSHFIELD RM 520	CHICAGO	IL	60612	COOK	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	001	16	11/16/2016	EXTENSION WITH OR WITHOUT FUNDS	$277,635
2017	2015	UNIVERSITY OF ILLINOIS	809 S MARSHFIELD RM 520	CHICAGO	IL	60612	COOK	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	15	11/16/2016	NON-COMPETING CONTINUATION	-$139,508
2017	2015	UNIVERSITY OF ILLINOIS	809 S MARSHFIELD RM 520	CHICAGO	IL	60612	COOK	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	002	15	11/16/2016	SUPPLEMENT FOR EXPANSION	-$138,127


Issue Date FY: 2016 ( Subtotal = $773,127 )
2016	2016	UNIVERSITY OF ILLINOIS AT CHICAGO	890 SOUTH MARSHFIELD AVENUE	CHICAGO	IL	60612	COOK	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	16	5/24/2016	EXTENSION WITH OR WITHOUT FUNDS	$773,127


Issue Date FY: 2015 ( Subtotal = $773,127 )
2015	2015	UNIVERSITY OF ILLINOIS AT CHICAGO	890 SOUTH MARSHFIELD AVENUE	CHICAGO	IL	60612	COOK	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	15	5/14/2015	NON-COMPETING CONTINUATION	$635,000
2015	2015	UNIVERSITY OF ILLINOIS AT CHICAGO	890 SOUTH MARSHFIELD AVENUE	CHICAGO	IL	60612	COOK	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	001	15	8/26/2015	SUPPLEMENT FOR EXPANSION	$138,127


Issue Date FY: 2014 ( Subtotal = $635,000 )
2014	2014	UNIVERSITY OF ILLINOIS AT CHICAGO	890 SOUTH MARSHFIELD AVENUE	CHICAGO	IL	60612	COOK	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	14	7/17/2014	NON-COMPETING CONTINUATION	$635,000


Issue Date FY: 2013 ( Subtotal = $635,000 )
2013	2013	UNIVERSITY OF ILLINOIS AT CHICAGO	890 SOUTH MARSHFIELD AVENUE	CHICAGO	IL	60612	COOK	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	001	13	8/16/2013	COMPETING CONTINUATION	$635,000
2013	2012	UNIVERSITY OF ILLINOIS AT CHICAGO	890 SOUTH MARSHFIELD AVENUE	CHICAGO	IL	60612	COOK	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	12	8/15/2013	NON-COMPETING CONTINUATION	$0


Issue Date FY: 2012 ( Subtotal = $769,540 )
2012	2012	UNIVERSITY OF ILLINOIS AT CHICAGO	890 SOUTH MARSHFIELD AVENUE	CHICAGO	IL	60612	COOK	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	001	12	7/19/2012	NON-COMPETING CONTINUATION	$636,731
2012	2012	UNIVERSITY OF ILLINOIS AT CHICAGO	890 SOUTH MARSHFIELD AVENUE	CHICAGO	IL	60612	COOK	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	002	12	9/4/2012	SUPPLEMENT FOR EXPANSION	$132,809
2012	2011	UNIVERSITY OF ILLINOIS AT CHICAGO	890 SOUTH MARSHFIELD AVENUE	CHICAGO	IL	60612	COOK	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	11	2/10/2012	NON-COMPETING CONTINUATION	$0


Issue Date FY: 2011 ( Subtotal = $772,096 )
2011	2011	UNIVERSITY OF ILLINOIS AT CHICAGO	890 SOUTH MARSHFIELD AVENUE	CHICAGO	IL	60612	COOK	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	11	9/2/2011	NON-COMPETING CONTINUATION	$772,096


Issue Date FY: 2010 ( Subtotal = $787,584 )
2010	2010	UNIVERSITY OF ILLINOIS AT CHICAGO	890 SOUTH MARSHFIELD AVENUE	CHICAGO	IL	60612	COOK	USA	Kidney Diseases, Urology and Hematology Research	001	10	8/24/2010	NON-COMPETING CONTINUATION	$646,731
2010	2010	UNIVERSITY OF ILLINOIS AT CHICAGO	890 SOUTH MARSHFIELD AVENUE	CHICAGO	IL	60612	COOK	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	002	10	9/7/2010	SUPPLEMENT FOR EXPANSION	$140,853
2010	2009	UNIVERSITY OF ILLINOIS AT CHICAGO	890 SOUTH MARSHFIELD AVENUE	CHICAGO	IL	60612	COOK	USA	Kidney Diseases, Urology and Hematology Research	000	9	12/8/2009	NON-COMPETING CONTINUATION	$0


Issue Date FY: 2009 ( Subtotal = $798,917 )
2009	2009	UNIVERSITY OF ILLINOIS AT CHICAGO	890 SOUTH MARSHFIELD AVENUE	CHICAGO	IL	60612	COOK	USA	Trans-NIH Recovery Act Research Support	002	9	9/21/2009	SUPPLEMENT FOR EXPANSION	$152,186
2009	2009	UNIVERSITY OF ILLINOIS AT CHICAGO	890 SOUTH MARSHFIELD AVENUE	CHICAGO	IL	60612	COOK	USA	Kidney Diseases, Urology and Hematology Research	001	9	9/2/2009	NON-COMPETING CONTINUATION	$646,731
2009	2008	UNIVERSITY OF ILLINOIS AT CHICAGO	890 SOUTH MARSHFIELD AVENUE	CHICAGO	IL	60612	COOK	USA	Kidney Diseases, Urology and Hematology Research	000	8	4/13/2009	COMPETING CONTINUATION	$0


Issue Date FY: 2008 ( Subtotal = $646,732 )
2008	2008	UNIVERSITY OF ILLINOIS AT CHICAGO	890 SOUTH MARSHFIELD AVENUE	CHICAGO	IL	60612	COOK	USA	Kidney Diseases, Urology and Hematology Research	000	8	9/8/2008	COMPETING CONTINUATION	$646,732


Grand Total All Awards = $14,248,399

Sum of Action Amount is $14,248,399;

Grand Total = $14,248,399

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Continuation of the UIC Chronic Renal Insufficiency Cohort Clinical Center

Award Number: U01DK060980

ORGANIZATION: NATIONAL INSTITUTE OF DIABETES & DIGESTIVE & KIDNEY DISEASES

OPDIV: NIH

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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