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Oral Inflammation and Functional Gastrointestinal Disorders: A Practice-Based Reseach Approach

Award Number: U01DE033265
ORGANIZATION: NATIONAL INSTITUTE OF DENTAL AND CRANIOFACIAL RESEARCH
OPDIV: NIH
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 09/13/2023
PERIOD OF PERFORMANCE END DATE: 06/30/2028

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Oral Inflammation and Functional Gastrointestinal Disorders: A Practice-Based Reseach Approach - PROJECT SUMMARY: The overarching goal of this project is to develop organized, sustainable clinical research programs that enable faculty and students to conduct practice-based research at the Midwestern University Colleges of Dental Medicine. It is expected that once students graduate from these two dental schools, they will be adequately trained to fully participate in the National Dental PBRN. To accomplish this goal, this project will form a partnership between the two independently operated dental schools that are part of Midwestern University (MWU) Colleges of Dental Medicine (the College of Dental Medicine-AZ in Glendale, AZ, and the College of Dental Medicine-IL in Downers Grove, IL)) and an inter-institutional partner: the University of Chicago (UC) Biological Sciences Division Center for Health and the Social Sciences Program in Oral Health (CHeSS POH). In Approach Area 1, we will leverage the expertise and resources of the UC CHeSS POH to provide foundational clinical research training to clinical faculty and student teams at both dental schools. Concurrently, MWU will develop an infrastructure of video recorded training materials and a mentor network of research-oriented faculty to provide sustainability to this program by making clinical research training a fundamental component of the institution and dental student education. In Approach Area 2, we will build upon the existing intra-institutional collaboration between both MWU dental schools, which already share a common Research Team comprised of research-oriented faculty and laboratory technicians. We will expand this team to include CHeSS POH members as inter-institutional partners and work collaboratively to mentor clinical faculty and students in the conduct of practice-based research. In Approach Area 3, we will expand the current faculty mentor-dental student pairing that occurs at both dental schools when students enter their third year of education. Each incoming 3rd-year student is paired with a 4th-year student already working in the clinic. These two students work for the remainder of the year as clinical colleagues under the direct supervision of a specific clinical faculty member. By training a cohort of students each year to conduct clinical research under the mentorship of a research-trained faculty member, the program will produce competent clinical researchers entering the workforce as well as a research mentor network that fosters clinical research activities in both schools. In Approach Area 4, we will provide practical experience for the faculty/student research mentor system by conducting a practice-based research project wherein we systematically measure longitudinal relationships between oral inflammation and functional gastrointestinal disorders. This multisite, noninterventional prospective clinical study will provide applied training in day-to-day study operations, including consenting, enrolling, and data collection. Upon successful completion of this project, we will have built a sustainable, enduring clinical training program that will produce approximately 32 practice-based research trained new dental practitioners every year.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $668,014 )
2025	2025	MIDWESTERN UNIVERSITY	19555 N. 59TH AVE ADMINISTRATION BUILDING	GLENDALE	AZ	85308	MARICOPA	USA	Oral Diseases and Disorders Research	001	3	5/15/2025	NON-COMPETING CONTINUATION	$668,014
2025	2024	MIDWESTERN UNIVERSITY	19555 N. 59TH AVE ADMINISTRATION BUILDING	GLENDALE	AZ	85308	MARICOPA	USA	Oral Diseases and Disorders Research	000	2	3/13/2025	NON-COMPETING CONTINUATION	$0
														Subtotal = $668,014

Issue Date FY: 2024 ( Subtotal = $633,406 )
2024	2024	MIDWESTERN UNIVERSITY	19555 N. 59TH AVE ADMINISTRATION BUILDING	GLENDALE	AZ	85308	MARICOPA	USA	Oral Diseases and Disorders Research	001	2	7/30/2024	NON-COMPETING CONTINUATION	$670,458
2024	2023	MIDWESTERN UNIVERSITY	19555 N. 59TH AVE ADMINISTRATION BUILDING	GLENDALE	AZ	85308	MARICOPA	USA	Oral Diseases and Disorders Research	000	1	5/9/2024	NEW	-$37,052
														Subtotal = $633,406

Issue Date FY: 2023 ( Subtotal = $770,149 )
2023	2023	MIDWESTERN UNIVERSITY	19555 N. 59TH AVE,	GLENDALE	AZ	85308	MARICOPA	USA	Oral Diseases and Disorders Research	001	1	9/14/2023	NEW	$0
2023	2023	MIDWESTERN UNIVERSITY	19555 N. 59TH AVE,	GLENDALE	AZ	85308	MARICOPA	USA	Oral Diseases and Disorders Research	000	1	9/13/2023	NEW	$770,149
														Subtotal = $770,149

Grand Total All Awards = $2,071,569

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Oral Inflammation and Functional Gastrointestinal Disorders: A Practice-Based Reseach Approach

Award Number: U01DE033265

ORGANIZATION: NATIONAL INSTITUTE OF DENTAL AND CRANIOFACIAL RESEARCH

OPDIV: NIH

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 09/13/2023

PERIOD OF PERFORMANCE END DATE: 06/30/2028

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