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Maximizing outcomes for preschoolers with developmental language disorder: testing the effects of a sequentially targeted naturalistic intervention

Award Number: U01DC017135
ORGANIZATION: NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS
OPDIV: NIH
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 08/16/2018
PERIOD OF PERFORMANCE END DATE: 07/31/2025

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Maximizing outcomes for preschoolers with developmental language disorder: testing the effects of a sequentially targeted naturalistic intervention - PROJECT SUMMARY Between 7-10% of children have developmental language disorders (DLD) without other developmental concerns at kindergarten entry,1,2 which place them at significant risk for poor academic and social outcomes across the school years and into adulthood.3 Brief naturalistic intervention can significantly increase expressive vocabulary in toddlers with receptive and expressive language delays,4 but it is not sufficient to reduce the developmental gaps in vocabulary or syntax.5 No studies to date have examined the potential of sustained early intervention for maximizing language outcomes. The proposed study will: (a) evaluate the effects of a sequential language intervention on the vocabulary and grammar of young children at risk for developmental language disorder (DLD) and (b) examine moderators and mediators of intervention effects. The proposed hybrid intervention (EMT-SF) provides an empirically-supported intervention, Enhanced Milieu Teaching (EMT), blended with a theoretically-motivated, sentence-focused (SF) sequence of treatment targets6,7 and new input modification strategies.8,9 The central hypothesis is that intervention will result in greater vocabulary and grammar outcomes for children at high risk for DLD in the treatment group. The proposed research is a stratified randomized clinical trial comparing the effects of the EMT-SF intervention, implemented by parents and therapists, to a control condition and enrolling 108, 30-month-old children and their parents. Four specific aims guide the study: 1. Compare differences in vocabulary and grammar outcomes in treatment vs control children at 48 months of age. 2. Determine the extent to which parent language input and parental use of intervention strategies mediate child language outcomes. 3. Determine the extent to which child-level factors and child progress during intervention predict language outcomes 4. Determine the extent to which the intervention impacts broader aspects of spoken language and behavior related to literacy and school readiness (decontextualized language, narrative abilities, behavior problems) (exploratory). IMPACT: This study will determine if sustained early intervention can reduce the long-term risks of DLD, will inform developmental theory, and provide critical information that may transform preschool service delivery models.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = -$8,494 )
2026	2022	VANDERBILT UNIVERSITY	110 21ST AVE S	NASHVILLE	TN	37203	DAVIDSON	USA	Research Related to Deafness and Communication Disorders	000	5	12/10/2025	NON-COMPETING CONTINUATION	-$8,494
														Subtotal = -$8,494

Issue Date FY: 2024 ( Subtotal = $0 )
2024	2023	VANDERBILT UNIVERSITY	110 21ST AVE S	NASHVILLE	TN	37203	DAVIDSON	USA	Research Related to Deafness and Communication Disorders	002	5	7/15/2024	SUPPLEMENT FOR EXPANSION	$0
2024	2022	VANDERBILT UNIVERSITY	110 21ST AVE S	NASHVILLE	TN	37203	DAVIDSON	USA	Research Related to Deafness and Communication Disorders	001	5	7/12/2024	SUPPLEMENT FOR EXPANSION	$0
2024	2022	VANDERBILT UNIVERSITY	110 21ST AVE S	NASHVILLE	TN	37203	DAVIDSON	USA	Research Related to Deafness and Communication Disorders	000	5	7/11/2024	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2023 ( Subtotal = $1,119,390 )
2023	2023	VANDERBILT UNIVERSITY	110 21ST AVE S	NASHVILLE	TN	37203	DAVIDSON	USA	Research Related to Deafness and Communication Disorders	003	5	9/11/2023	SUPPLEMENT FOR EXPANSION	$1,119,390
2023	2023	VANDERBILT UNIVERSITY	110 21ST AVE S	NASHVILLE	TN	37203	DAVIDSON	USA	Research Related to Deafness and Communication Disorders	004	5	9/14/2023	SUPPLEMENT FOR EXPANSION	$0
2023	2022	VANDERBILT UNIVERSITY	110 21ST AVE S	NASHVILLE	TN	37203	DAVIDSON	USA	Research Related to Deafness and Communication Disorders	002	5	8/24/2023	NON-COMPETING CONTINUATION	$0
2023	2021	VANDERBILT UNIVERSITY	110 21ST AVE S	NASHVILLE	TN	37203	DAVIDSON	USA	Research Related to Deafness and Communication Disorders	001	4	7/16/2023	NON-COMPETING CONTINUATION	$0
2023	2020	VANDERBILT UNIVERSITY	110 21ST AVE S	NASHVILLE	TN	37203	DAVIDSON	USA	Research Related to Deafness and Communication Disorders	000	3	7/15/2023	NON-COMPETING CONTINUATION	$0
														Subtotal = $1,119,390

Issue Date FY: 2022 ( Subtotal = $1,241,917 )
2022	2022	VANDERBILT UNIVERSITY, THE	110 21ST AVENUE S STE 800	NASHVILLE	TN	37203	DAVIDSON	USA	Research Related to Deafness and Communication Disorders	001	5	8/8/2022	NON-COMPETING CONTINUATION	$1,085,913
2022	2022	VANDERBILT UNIVERSITY, THE	110 21ST AVENUE S STE 800	NASHVILLE	TN	37203	DAVIDSON	USA	Research Related to Deafness and Communication Disorders	002	5	8/9/2022	SUPPLEMENT FOR EXPANSION	$156,004
2022	2022	VANDERBILT UNIVERSITY, THE	110 21ST AVENUE S STE 800	NASHVILLE	TN	37203	DAVIDSON	USA	Research Related to Deafness and Communication Disorders	003	5	8/11/2022	NON-COMPETING CONTINUATION	$0
2022	2020	VANDERBILT UNIVERSITY, THE	110 21ST AVENUE S STE 800	NASHVILLE	TN	37203	DAVIDSON	USA	Research Related to Deafness and Communication Disorders	000	3	12/1/2021	NON-COMPETING CONTINUATION	$0
														Subtotal = $1,241,917

Issue Date FY: 2021 ( Subtotal = $1,225,534 )
2021	2021	VANDERBILT UNIVERSITY, THE	110 21ST AVENUE S STE 800	NASHVILLE	TN	37203	DAVIDSON	USA	Research Related to Deafness and Communication Disorders	000	4	7/28/2021	NON-COMPETING CONTINUATION	$1,225,534
														Subtotal = $1,225,534

Issue Date FY: 2020 ( Subtotal = $1,271,678 )
2020	2020	VANDERBILT UNIVERSITY, THE	110 21ST AVENUE S STE 800	NASHVILLE	TN	37203	DAVIDSON	USA	Research Related to Deafness and Communication Disorders	000	3	8/18/2020	NON-COMPETING CONTINUATION	$1,271,678
														Subtotal = $1,271,678

Issue Date FY: 2019 ( Subtotal = $1,293,944 )
2019	2019	VANDERBILT UNIVERSITY, THE	110 21ST AVENUE S STE 800	NASHVILLE	TN	37203	DAVIDSON	USA	Research Related to Deafness and Communication Disorders	001	2	7/31/2019	NON-COMPETING CONTINUATION	$0
2019	2019	VANDERBILT UNIVERSITY, THE	110 21ST AVENUE S STE 800	NASHVILLE	TN	37203	DAVIDSON	USA	Research Related to Deafness and Communication Disorders	000	2	7/25/2019	NON-COMPETING CONTINUATION	$1,293,944
														Subtotal = $1,293,944

Issue Date FY: 2018 ( Subtotal = $1,237,542 )
2018	2018	VANDERBILT UNIVERSITY, THE	110 21ST AVENUE S STE 800	NASHVILLE	TN	37203	DAVIDSON	USA	Research Related to Deafness and Communication Disorders	000	1	8/16/2018	NEW	$1,237,542
														Subtotal = $1,237,542

Grand Total All Awards = $7,381,511

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Maximizing outcomes for preschoolers with developmental language disorder: testing the effects of a sequentially targeted naturalistic intervention

Award Number: U01DC017135

ORGANIZATION: NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS

OPDIV: NIH

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 08/16/2018

PERIOD OF PERFORMANCE END DATE: 07/31/2025

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