Friday, November 22, 2024 11/22/2024

An Integrated and Individual Tick Management Program to Reduce Risk of Lyme Disea

Award Number: U01CK000182
ORGANIZATION: NATIONAL CENTER FOR ZOONOTIC, VECTOR-BORNE, AND ENTERIC DISEASES
OPDIV: CDC
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

Group Awards By:

View Award Abstract

DESCRIPTION (provided by applicant): Lyme disease (LD) is the most important tick-associated disease in the United States. A variety of prevention and control methods, including personal protective measures, habitat modification, applications of biological and natural compounds, and host-targeted control measures, have been examined for reducing tick abundance and risk for LD. The primary aim of this proposal is to develop, implement, and evaluate individual and integrated tick management (ITM) approaches to reduce the entomological risk of LD. In addition, an enhanced LD decision support system will be constructed by incorporating the new findings obtained from the proposed project. The practical application of an effective tick bite protection program requires easy public access to decision support tools for promoting widespread usage of tick control strategies. We propose to examine the efficacy and associated costs of several existing and new tick control measures individually as well in the framework of the ITM approach to reduce the number of infected ticks in the inland LD endemic neighborhoods. An economic cost-benefit analysis for tick management and LD will involve costs associated with medical expenses for diagnosis, treatment, and productivity losses versus costs of prevention and control. The proposed ITM approach is a novel combination of applications of biological (insect pathogenic fungus) and natural less-toxic compounds, pesticides, habitat modification, and host reduction. We will improve upon the timing and frequency of spray applications by analyzing the residual activity of natural compounds in comparison with synthetic products. In addition, we have developed molecular techniques to identify hosts of tick vectors to directly estimate vector-contact with different vertebrate species, which is essential for evaluating their relative importance as reservoir hosts for LD and other tick-associated diseases. Furthermore, by taking advantage of a molecular epidemiological approach, we will track the temporal distribution of the LD- causing spirochetes and other pathogens in tick populations and reservoir hosts in conjunction with our tick management program. In short, by adapting a novel ITM strategy, we will examine and compare shared and dissimilar components of an ITM approach for LD control. By incorporating entomological data and other information acquired by the proposed project into our decision support system, we will provide guidance on the most effective control measures that will help stakeholders to protect themselves in an environmentally safe manner. The approach and findings generated from this project will easily be extended to other LD endemic regions. Keywords: blacklegged tick; ITM; Lyme disease; biological control; landscape management; blood-meal analysis; pathogen screening; cost-benefit analysis; deer management; decision support system.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2016 ( Subtotal = $0 )
2016	2014	THE CONNECTICUT AGRICULTURAL EXPERIMENT STATION	123 HUNTINGTON ST, PO BOX 1106	NEW HAVEN	CT	06504	SOUTH CENTRAL CT	USA	Research, Prevention, and Education Programs on Lyme Disease in the United States	000	3	8/3/2016	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2015 ( Subtotal = $0 )
2015	2014	THE CONNECTICUT AGRICULTURAL EXPERIMENT STATION	123 HUNTINGTON ST, PO BOX 1106	NEW HAVEN	CT	06504	SOUTH CENTRAL CT	USA	Research, Prevention, and Education Programs on Lyme Disease in the United States	000	3	4/2/2015	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2014 ( Subtotal = $375,000 )
2014	2014	THE CONNECTICUT AGRICULTURAL EXPERIMENT STATION	123 HUNTINGTON ST, PO BOX 1106	NEW HAVEN	CT	06511	SOUTH CENTRAL CT	USA	Research, Prevention, and Education Programs on Lyme Disease in the United States	000	3	7/14/2014	NON-COMPETING CONTINUATION	$375,000
														Subtotal = $375,000

Issue Date FY: 2013 ( Subtotal = $300,000 )
2013	2013	THE CONNECTICUT AGRICULTURAL EXPERIMENT STATION	123 HUNTINGTON ST, PO BOX 1106	NEW HAVEN	CT	06511	SOUTH CENTRAL CT	USA	Research, Prevention, and Education Programs on Lyme Disease in the United States	001	2	8/5/2013	NON-COMPETING CONTINUATION	$300,000
2013	2012	THE CONNECTICUT AGRICULTURAL EXPERIMENT STATION	123 HUNTINGTON ST, PO BOX 1106	NEW HAVEN	CT	06504	SOUTH CENTRAL CT	USA	Research, Prevention, and Education Programs on Lyme Disease in the United States	000	1	10/25/2012	NEW	$0
														Subtotal = $300,000

Issue Date FY: 2012 ( Subtotal = $300,000 )
2012	2012	THE CONNECTICUT AGRICULTURAL EXPERIMENT STATION	123 HUNTINGTON ST, PO BOX 1106	NEW HAVEN	CT	06504	SOUTH CENTRAL CT	USA	Research, Prevention, and Education Programs on Lyme Disease in the United States	001	1	10/25/2012	NEW	$0
2012	2012	THE CONNECTICUT AGRICULTURAL EXPERIMENT STATION	123 HUNTINGTON ST, PO BOX 1106	NEW HAVEN	CT	06511	SOUTH CENTRAL CT	USA	Research, Prevention, and Education Programs on Lyme Disease in the United States	000	1	8/1/2012	NEW	$300,000
														Subtotal = $300,000

Grand Total All Awards = $975,000

Top

All Categories

About

Search

Reports

Data Submission

Award Information

An Integrated and Individual Tick Management Program to Reduce Risk of Lyme Disea

Award Number: U01CK000182

ORGANIZATION: NATIONAL CENTER FOR ZOONOTIC, VECTOR-BORNE, AND ENTERIC DISEASES

OPDIV: CDC

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

Federal Websites

Department of Health & Human Services

HHS Operating Divisions

HHS Staff Divisions

Download A Document Viewer