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IMPLEMENTATION RESEARCH FOR MANAGEMENT OF MALARIA AND CHILDHOOD ILLNESS/TANZANIA

Award Number: U01CK000128
ORGANIZATION: NATIONAL CENTER FOR ZOONOTIC, VECTOR-BORNE, AND ENTERIC DISEASES
OPDIV: CDC
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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DESCRIPTION (provided by applicant): Since 2000, CDC and the Ifakara Health Research and Development Centre (IHRDC), recently renamed Ifakara Health Institute (IHI) have operated a series of malaria control and research collaborations, leading directly to substantial gains in child survival across wide parts of southern Tanzania. This application proposes a revived implementation research agenda that will support malaria policy makers and other public health officials in Tanzania and throughout subSaharan Africa to address three important objectives: 1. to address the opimal mix of currently validated malaria control interventions across malaria transmission zones and diverse epidemiological and cultural settings. 2. to rapidly develop and validate the impact of revised, enhanced or novel interventions that will contribute to effective malaria control at scale. 3. to establish the most feasible and effective opportunities for integration with other US Government supported child survival, environmental health, vector control and infectious disease programs. Through an interdisciplinary research team and strong links with national and local health authorities, CDC and IHI/ IHRDC have already helped to establish a strong rational for universal distribution of insecticide treated bednets, a workable plan for deployment and quality assurance of rapid diagnostic tests for malaria, and established the first programmatic introduction of artemisinin containing combination therapies for malaria. We propose to build upon the partnership that was established to achieve these milestones and apply our attention to new and potentially life-sparing innovations such as improved detection of antimalarial drug resistance, enhanced guidelines for managing sick children without evidence of malaria infection, and maintaining our decades-long effort to document the reach and impact of malaria control and child survival interventions. Details of the research plan are outlined in the continuation pages.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2019 ( Subtotal = -$102,863 )
2019	2013	IFAKARA HEALTH INSTITUTE	KIKO ROAD	DAR ES SALAAM				TZA	Centers for Disease Control and Prevention Investigations and Technical Assistance	01	5	9/10/2019	ADMINISTRATIVE SUPPLEMENT ( + OR - ) (DISCRETIONARY OR BLOCK AWARDS)	-$50,000
2019	2012	IFAKARA HEALTH INSTITUTE	KIKO ROAD	DAR ES SALAAM				TZA	Centers for Disease Control and Prevention Investigations and Technical Assistance	01	5	9/10/2019	ADMINISTRATIVE SUPPLEMENT ( + OR - ) (DISCRETIONARY OR BLOCK AWARDS)	-$52,863
2019	2011	IFAKARA HEALTH INSTITUTE	KIKO ROAD	DAR ES SALAAM				TZA	Centers for Disease Control and Prevention Investigations and Technical Assistance	01	5	9/10/2019	ADMINISTRATIVE SUPPLEMENT ( + OR - ) (DISCRETIONARY OR BLOCK AWARDS)	$0
2019	2010	IFAKARA HEALTH INSTITUTE	KIKO ROAD	DAR ES SALAAM				TZA	Centers for Disease Control and Prevention Investigations and Technical Assistance	01	5	9/10/2019	ADMINISTRATIVE SUPPLEMENT ( + OR - ) (DISCRETIONARY OR BLOCK AWARDS)	$0
2019	2009	IFAKARA HEALTH INSTITUTE	KIKO ROAD	DAR ES SALAAM				TZA	Centers for Disease Control and Prevention Investigations and Technical Assistance	01	5	9/10/2019	ADMINISTRATIVE SUPPLEMENT ( + OR - ) (DISCRETIONARY OR BLOCK AWARDS)	$0
														Subtotal = -$102,863

Issue Date FY: 2013 ( Subtotal = $50,000 )
2013	2013	IFAKARA HEALTH RESEARCH & DEVELOPMENT CENTER	PO BOX 53	DAR-ES-SALAAM				TZA	Centers for Disease Control and Prevention Investigations and Technical Assistance	001	5	8/13/2013	NON-COMPETING CONTINUATION	$50,000
2013	2012	IFAKARA HEALTH RESEARCH & DEVELOPMENT CENTER	PO BOX 53	TANZANIA					Centers for Disease Control and Prevention Investigations and Technical Assistance	000	4	8/9/2013	NON-COMPETING CONTINUATION	$0
														Subtotal = $50,000

Issue Date FY: 2012 ( Subtotal = $143,000 )
2012	2012	IFAKARA HEALTH RESEARCH & DEVELOPMENT CENTER	PO BOX 53	DAR-ES-SALAAM				TZA	Centers for Disease Control and Prevention Investigations and Technical Assistance	000	4	8/29/2012	NON-COMPETING CONTINUATION	$143,000
														Subtotal = $143,000

Issue Date FY: 2011 ( Subtotal = $220,000 )
2011	2011	IFAKARA HEALTH RESEARCH & DEVELOPMENT CENTER	PO BOX 53	DAR-ES-SALAAM				TZA	Centers for Disease Control and Prevention Investigations and Technical Assistance	000	3	9/7/2011	NON-COMPETING CONTINUATION	$220,000
														Subtotal = $220,000

Issue Date FY: 2010 ( Subtotal = $480,000 )
2010	2010	IFAKARA HEALTH RESEARCH & DEVELOPMENT CENTER	PO BOX 53	DAR-ES-SALAAM				TZA	Centers for Disease Control and Prevention Investigations and Technical Assistance	000	2	7/14/2010	NON-COMPETING CONTINUATION	$480,000
														Subtotal = $480,000

Issue Date FY: 2009 ( Subtotal = $435,000 )
2009	2009	IFAKARA HEALTH RESEARCH & DEVELOPMENT CENTER	PO BOX 53	DAR-ES-SALAAM				TZA	Centers for Disease Control and Prevention Investigations and Technical Assistance	000	1	8/28/2009	NEW	$435,000
														Subtotal = $435,000

Grand Total All Awards = $1,225,137

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IMPLEMENTATION RESEARCH FOR MANAGEMENT OF MALARIA AND CHILDHOOD ILLNESS/TANZANIA

Award Number: U01CK000128

ORGANIZATION: NATIONAL CENTER FOR ZOONOTIC, VECTOR-BORNE, AND ENTERIC DISEASES

OPDIV: CDC

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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