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The ECOG-ACRIN SUPPORT Trial: Multilevel Intervention to Improve Diverse Enrollment in Cancer Clinical Trials

Award Number: U01CA274996
ORGANIZATION: NATIONAL CANCER INSTITUTE
OPDIV: NIH
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 09/15/2022
PERIOD OF PERFORMANCE END DATE: 08/31/2028

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The ECOG-ACRIN SUPPORT Trial: Multilevel Intervention to Improve Diverse Enrollment in Cancer Clinical Trials - ABSTRACT National Cancer Institute (NCI) supported clinical trials (CTs) are key drivers of innovations in cancer care; however limited participation in NCI-supported CTs reduces reach and thus some are not able to fully benefit from cutting edge treatments and precision medicine. CT participation continues to fall short and the multitude of structural, clinical, physician, and patient barriers warrant multilevel interventions to enhance referral and enrollment to NCI-supported CTs. The ECOG-ACRIN Cancer Research Group (EA), as an NCORP Research Base, has engaged community providers and researchers through a robust research portfolio that spans Cancer Control, Cancer Prevention, and Cancer Care Delivery. We propose to leverage the collective resources of the EA, our team’s decades of work on improving participation in clinical trials, and our foundational work in patient navigation and CT research literacy tools to create and evaluate an ECOG-ACRIN Trial SUPPORT Toolkit (SUPPORT intervention) that aims to improve referral and enrollment in active NCI-supported therapeutic trials. The multilevel EA SUPPORT intervention consists of a CT research literacy tool and CT Resource Navigators who will interface with patients, providers, and community oncology site staff to improve referral and enrollment to CTs.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $701,000 )
2025	2025	ECOG-ACRIN MEDICAL RESEARCH FOUNDATION, INC.	1818 MARKET ST STE 3000	PHILADELPHIA	PA	19103	PHILADELPHIA	USA	Cancer Cause and Prevention Research	001	4	8/1/2025	NON-COMPETING CONTINUATION	$701,000
2025	2024	ECOG-ACRIN MEDICAL RESEARCH FOUNDATION, INC.	1818 MARKET ST STE 3000	PHILADELPHIA	PA	19103	PHILADELPHIA	USA	Cancer Cause and Prevention Research	000	3	7/31/2025	NON-COMPETING CONTINUATION	$0
														Subtotal = $701,000

Issue Date FY: 2024 ( Subtotal = $349,468 )
2024	2024	ECOG-ACRIN MEDICAL RESEARCH FOUNDATION, INC.	1818 MARKET ST STE 3000	PHILADELPHIA	PA	19103	PHILADELPHIA	USA	Cancer Cause and Prevention Research	001	3	9/4/2024	NON-COMPETING CONTINUATION	$349,468
2024	2023	ECOG-ACRIN MEDICAL RESEARCH FOUNDATION, INC.	1818 MARKET ST STE 3000	PHILADELPHIA	PA	19103	PHILADELPHIA	USA	Cancer Cause and Prevention Research	000	2	3/12/2024	NON-COMPETING CONTINUATION	$0
														Subtotal = $349,468

Issue Date FY: 2023 ( Subtotal = $690,281 )
2023	2023	ECOG-ACRIN MEDICAL RESEARCH FOUNDATION, INC.	1818 MARKET ST STE 3000	PHILADELPHIA	PA	19103	PHILADELPHIA	USA	Cancer Cause and Prevention Research	000	2	8/17/2023	NON-COMPETING CONTINUATION	$690,281
														Subtotal = $690,281

Issue Date FY: 2022 ( Subtotal = $736,717 )
2022	2022	ECOG-ACRIN MEDICAL RESEARCH FOUNDATION, INC.	1818 MARKET ST STE 3000	PHILADELPHIA	PA	19103	PHILADELPHIA	USA	Cancer Cause and Prevention Research	000	1	9/15/2022	NEW	$736,717
														Subtotal = $736,717

Grand Total All Awards = $2,477,466

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The ECOG-ACRIN SUPPORT Trial: Multilevel Intervention to Improve Diverse Enrollment in Cancer Clinical Trials

Award Number: U01CA274996

ORGANIZATION: NATIONAL CANCER INSTITUTE

OPDIV: NIH

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 09/15/2022

PERIOD OF PERFORMANCE END DATE: 08/31/2028

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