Monday, June 30, 2025 6/30/2025

"Sao Paulo-Minas Gerais Center for Chagas Disease Treatment (SaMiTrop)"

Award Number: U01AI168383
ORGANIZATION: NATIONAL INSTITUTE OF ALLERGY & INFECTIOUS DISEASES
OPDIV: NIH
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 04/01/2022
PERIOD OF PERFORMANCE END DATE: 03/31/2027

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"Sao Paulo-Minas Gerais Center for Chagas Disease Treatment (SaMiTrop)" - ABSTRACT Chagas disease (CD) remains one of the most neglected illnesses in the world, with estimates indicating 5.7 million infected people in Latin and Central America. Currently, there are many barriers that patients with CD have to overcome to obtain a diagnosis, adequate treatment, and appropriate follow-up. One of the main ones is the high rate of underdiagnosis and consequently of patients treated. It is estimated that less than 10% of patients are diagnosed and that less than 1% are treated. Furthermore, to date, there is no reliable method that allows measuring therapeutic efficacy. During the last 15 years, researchers from the São Paulo-Minas Gerais Tropical Medicine Research Center (SaMi-Trop) have developed numerous projects that have evidenced the high number of patients in an endemic area in the north of the State of Minas Gerais, in addition to providing valuable information on the natural history of CD, the rate of progression to cardiomyopathy and its relationship with antibody levels. A great key to the success of such initiatives has been their strategic articulation with primary health care, which has made it possible to have large cohorts of patients accompanied for more than 10 years. Therefore, it is intended in this project to apply all this knowledge and articulation to identify methodologies and tools that allow overcoming existing barriers. The results obtained will make it possible to increase the number of diagnosed patients to whom treatment will be offered and identify strategies and biomarkers that make it possible to improve patient follow-up and help evaluate new treatment candidates.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $388,653 )
2025	2025	FUNDACAO FACULDADE DE MEDICINA	AVENIDA REBOUCAS 381	SAO PAULO				BRA	Allergy and Infectious Diseases Research	000	4	4/10/2025	NON-COMPETING CONTINUATION	$388,653
														Subtotal = $388,653

Issue Date FY: 2024 ( Subtotal = $388,653 )
2024	2024	FUNDACAO FACULDADE DE MEDICINA	AVENIDA REBOUCAS 381	SAO PAULO				BRA	Allergy and Infectious Diseases Research	000	3	4/24/2024	NON-COMPETING CONTINUATION	$388,653
2024	2024	FUNDACAO FACULDADE DE MEDICINA	AVENIDA REBOUCAS 381	SAO PAULO				BRA	Allergy and Infectious Diseases Research	001	3	7/29/2024	NON-COMPETING CONTINUATION	$0
														Subtotal = $388,653

Issue Date FY: 2023 ( Subtotal = $388,653 )
2023	2023	FUNDACAO FACULDADE DE MEDICINA	AV REBOUCAS 381	SAO PAULO				BRA	Allergy and Infectious Diseases Research	000	2	3/16/2023	NON-COMPETING CONTINUATION	$388,653
														Subtotal = $388,653

Issue Date FY: 2022 ( Subtotal = $388,653 )
2022	2022	FUNDACAO FACULDADE DE MEDICINA.	AV. REBOUCAS 381	SAO PAULO	SP			BRA	Allergy and Infectious Diseases Research	000	1	3/15/2022	NEW	$388,653
														Subtotal = $388,653

Grand Total All Awards = $1,554,612

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"Sao Paulo-Minas Gerais Center for Chagas Disease Treatment (SaMiTrop)"

Award Number: U01AI168383

ORGANIZATION: NATIONAL INSTITUTE OF ALLERGY & INFECTIOUS DISEASES

OPDIV: NIH

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 04/01/2022

PERIOD OF PERFORMANCE END DATE: 03/31/2027

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