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Central Africa International Epidemiology databases to Evaluate AIDS

Award Number: U01AI096299
ORGANIZATION: NATIONAL INSTITUTE OF ALLERGY & INFECTIOUS DISEASES
OPDIV: NIH
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 07/15/2011
PERIOD OF PERFORMANCE END DATE: 05/31/2028

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Central Africa International Epidemiology databases to Evaluate AIDS - Project Summary As HIV care and treatment programs are implemented throughout sub-Saharan Africa (SSA), critical advances in research and policy are needed so that care and treatment resources can be deployed to optimal benefit: decreasing new HIV transmissions, HIV-related morbidity and mortality, and illness from non-communicable disease (NCD). Coverage of antiretroviral therapy in the 'Treat All' era varies widely in our region, from 87% in Rwanda to 25% in Republic of Congo, the lowest coverage among all IeDEA countries in SSA. Our research agenda is designed to generate actionable knowledge to help close these gaps. Our regional cohort database includes longitudinal data for 81,183 adults and 11,789 children ever enrolling in HIV care at 22 sites in Burundi, Cameroon, the Democratic Republic of Congo, Republic of Congo and Rwanda. We propose to supplement this database with linked cohorts to address a range of investigations relevant to our region including: 1) leveraging implementation science approaches to inform strategies aimed at improving HIV prevention, care and treatment outcomes in the region (Aim 1); 2) conducting in-depth clinical investigations of HIV-related outcomes and infectious (e.g. TB) and non-infectious (e.g. NCDs) comorbidities (Aim 2); 3) leading and supporting an innovative multiregional scientific agenda within the larger IeDEA network (Aim 3); and 4.) providing scientific and career mentoring to early stage investigators and researchers from Central Africa and from the US (Aim 4). Central Africa IeDEA has a diverse scientific team with broad and deep expertise in implementation science, epidemiology and clinical research. We have been highly productive scientifically with >45 publications across a range of topics, and have continued to foster African leadership and build local research capacity. Themes in our application include an emphasis on ‘treat all’ policy implementation, mental health and substance use (alcohol), PMTCT and pediatric and adolescent HIV, tuberculosis, HIV prevention through PrEP, and NCDs in aging people living with HIV (e.g. kidney disease).


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = $3,287,814 )
2026	2026	ALBERT EINSTEIN COLLEGE OF MEDICINE	1300 MORRIS PARK AVE	BRONX	NY	10461	BRONX	USA	Allergy and Infectious Diseases Research	011	18	7/10/2026	SUPPLEMENT FOR EXPANSION	$276,636
2026	2026	ALBERT EINSTEIN COLLEGE OF MEDICINE	1300 MORRIS PARK AVE	BRONX	NY	10461	BRONX	USA	Allergy and Infectious Diseases Research	010	18	7/9/2026	SUPPLEMENT FOR EXPANSION	$118,752
2026	2026	ALBERT EINSTEIN COLLEGE OF MEDICINE	1300 MORRIS PARK AVE	BRONX	NY	10461	BRONX	USA	Allergy and Infectious Diseases Research	015	18	7/24/2026	SUPPLEMENT FOR EXPANSION	$0
2026	2026	ALBERT EINSTEIN COLLEGE OF MEDICINE	1300 MORRIS PARK AVE	BRONX	NY	10461	BRONX	USA	Allergy and Infectious Diseases Research	013	18	7/14/2026	SUPPLEMENT FOR EXPANSION	$58,120
2026	2026	ALBERT EINSTEIN COLLEGE OF MEDICINE	1300 MORRIS PARK AVE	BRONX	NY	10461	BRONX	USA	Allergy and Infectious Diseases Research	014	18	7/15/2026	SUPPLEMENT FOR EXPANSION	$256,922
2026	2026	ALBERT EINSTEIN COLLEGE OF MEDICINE	1300 MORRIS PARK AVE	BRONX	NY	10461	BRONX	USA	Allergy and Infectious Diseases Research	012	18	7/13/2026	SUPPLEMENT FOR EXPANSION	$509,594
2026	2026	ALBERT EINSTEIN COLLEGE OF MEDICINE	1300 MORRIS PARK AVE	BRONX	NY	10461	BRONX	USA	Allergy and Infectious Diseases Research	009	18	6/27/2026	EXTENSION WITH OR WITHOUT FUNDS	$2,067,790
2026	2025	ALBERT EINSTEIN COLLEGE OF MEDICINE	1300 MORRIS PARK AVE	BRONX	NY	10461	BRONX	USA	Allergy and Infectious Diseases Research	003	17	4/15/2026	SUPPLEMENT FOR EXPANSION	$0
2026	2025	ALBERT EINSTEIN COLLEGE OF MEDICINE	1300 MORRIS PARK AVE	BRONX	NY	10461	BRONX	USA	Allergy and Infectious Diseases Research	001	17	4/15/2026	NON-COMPETING CONTINUATION	$0
2026	2025	ALBERT EINSTEIN COLLEGE OF MEDICINE	1300 MORRIS PARK AVE	BRONX	NY	10461	BRONX	USA	Allergy and Infectious Diseases Research	000	17	1/6/2026	NON-COMPETING CONTINUATION	$0
2026	2025	ALBERT EINSTEIN COLLEGE OF MEDICINE	1300 MORRIS PARK AVE	BRONX	NY	10461	BRONX	USA	Allergy and Infectious Diseases Research	002	17	4/15/2026	SUPPLEMENT FOR EXPANSION	$0
2026	2025	ALBERT EINSTEIN COLLEGE OF MEDICINE	1300 MORRIS PARK AVE	BRONX	NY	10461	BRONX	USA	Allergy and Infectious Diseases Research	005	17	4/15/2026	SUPPLEMENT FOR EXPANSION	$0
2026	2025	ALBERT EINSTEIN COLLEGE OF MEDICINE	1300 MORRIS PARK AVE	BRONX	NY	10461	BRONX	USA	Allergy and Infectious Diseases Research	004	17	4/15/2026	SUPPLEMENT FOR EXPANSION	$0
2026	2025	ALBERT EINSTEIN COLLEGE OF MEDICINE	1300 MORRIS PARK AVE	BRONX	NY	10461	BRONX	USA	Allergy and Infectious Diseases Research	008	17	6/18/2026	NON-COMPETING CONTINUATION	$0
2026	2025	ALBERT EINSTEIN COLLEGE OF MEDICINE	1300 MORRIS PARK AVE	BRONX	NY	10461	BRONX	USA	Allergy and Infectious Diseases Research	007	17	4/16/2026	NON-COMPETING CONTINUATION	$0
2026	2025	ALBERT EINSTEIN COLLEGE OF MEDICINE	1300 MORRIS PARK AVE	BRONX	NY	10461	BRONX	USA	Allergy and Infectious Diseases Research	006	17	4/15/2026	SUPPLEMENT FOR EXPANSION	$0
														Subtotal = $3,287,814

Issue Date FY: 2025 ( Subtotal = $2,900,000 )
2025	2025	ALBERT EINSTEIN COLLEGE OF MEDICINE	1300 MORRIS PARK AVE	BRONX	NY	10461	BRONX	USA	Allergy and Infectious Diseases Research	001	17	8/18/2025	NON-COMPETING CONTINUATION	$1,769,171
2025	2025	ALBERT EINSTEIN COLLEGE OF MEDICINE	1300 MORRIS PARK AVE	BRONX	NY	10461	BRONX	USA	Allergy and Infectious Diseases Research	002	17	8/20/2025	SUPPLEMENT FOR EXPANSION	$110,040
2025	2025	ALBERT EINSTEIN COLLEGE OF MEDICINE	1300 MORRIS PARK AVE	BRONX	NY	10461	BRONX	USA	Allergy and Infectious Diseases Research	005	17	8/22/2025	SUPPLEMENT FOR EXPANSION	$58,121
2025	2025	ALBERT EINSTEIN COLLEGE OF MEDICINE	1300 MORRIS PARK AVE	BRONX	NY	10461	BRONX	USA	Allergy and Infectious Diseases Research	003	17	8/21/2025	SUPPLEMENT FOR EXPANSION	$165,100
2025	2025	ALBERT EINSTEIN COLLEGE OF MEDICINE	1300 MORRIS PARK AVE	BRONX	NY	10461	BRONX	USA	Allergy and Infectious Diseases Research	006	17	8/22/2025	SUPPLEMENT FOR EXPANSION	$227,788
2025	2025	ALBERT EINSTEIN COLLEGE OF MEDICINE	1300 MORRIS PARK AVE	BRONX	NY	10461	BRONX	USA	Allergy and Infectious Diseases Research	004	17	8/22/2025	SUPPLEMENT FOR EXPANSION	$569,780
2025	2024	ALBERT EINSTEIN COLLEGE OF MEDICINE	1300 MORRIS PARK AVE	BRONX	NY	10461	BRONX	USA	Allergy and Infectious Diseases Research	000	16	11/6/2024	NON-COMPETING CONTINUATION	$0
														Subtotal = $2,900,000

Issue Date FY: 2024 ( Subtotal = $3,171,082 )
2024	2024	ALBERT EINSTEIN COLLEGE OF MEDICINE	1300 MORRIS PARK AVE	BRONX	NY	10461	BRONX	USA	Allergy and Infectious Diseases Research	002	16	7/15/2024	SUPPLEMENT FOR EXPANSION	$307,743
2024	2024	ALBERT EINSTEIN COLLEGE OF MEDICINE	1300 MORRIS PARK AVE	BRONX	NY	10461	BRONX	USA	Allergy and Infectious Diseases Research	001	16	4/10/2024	NON-COMPETING CONTINUATION	$2,900,000
2024	2020	ALBERT EINSTEIN COLLEGE OF MEDICINE	1300 MORRIS PARK AVE	BRONX	NY	10461	BRONX	USA	Allergy and Infectious Diseases Research	000	11	10/1/2023	SUPPLEMENT FOR EXPANSION	-$36,661
														Subtotal = $3,171,082

Issue Date FY: 2023 ( Subtotal = $3,899,752 )
2023	2023	ALBERT EINSTEIN COLLEGE OF MEDICINE	1300 MORRIS PARK AVE	BRONX	NY	10461	BRONX	USA	Allergy and Infectious Diseases Research	002	15	8/4/2023	NON-COMPETING CONTINUATION	$332,814
2023	2023	ALBERT EINSTEIN COLLEGE OF MEDICINE	1300 MORRIS PARK AVE	BRONX	NY	10461	BRONX	USA	Allergy and Infectious Diseases Research	000	15	4/11/2023	NON-COMPETING CONTINUATION	$3,011,512
2023	2023	ALBERT EINSTEIN COLLEGE OF MEDICINE	1300 MORRIS PARK AVE	BRONX	NY	10461	BRONX	USA	Allergy and Infectious Diseases Research	003	15	8/21/2023	SUPPLEMENT FOR EXPANSION	$555,426
2023	2023	ALBERT EINSTEIN COLLEGE OF MEDICINE	1300 MORRIS PARK AVE	BRONX	NY	10461	BRONX	USA	Allergy and Infectious Diseases Research	001	15	4/21/2023	NON-COMPETING CONTINUATION	$0
														Subtotal = $3,899,752

Issue Date FY: 2022 ( Subtotal = $3,050,000 )
2022	2022	ALBERT EINSTEIN COLLEGE OF MEDICINE	1300 MORRIS PARK AVE	BRONX	NY	10461	BRONX	USA	Allergy and Infectious Diseases Research	009	14	4/29/2022	NON-COMPETING CONTINUATION	$2,900,000
2022	2022	ALBERT EINSTEIN COLLEGE OF MEDICINE	1300 MORRIS PARK AVE	BRONX	NY	10461	BRONX	USA	Allergy and Infectious Diseases Research	011	14	7/14/2022	NON-COMPETING CONTINUATION	$150,000
2022	2022	ALBERT EINSTEIN COLLEGE OF MEDICINE	1300 MORRIS PARK AVE	BRONX	NY	10461	BRONX	USA	Allergy and Infectious Diseases Research	010	14	5/11/2022	NON-COMPETING CONTINUATION	$0
2022	2021	ALBERT EINSTEIN COLLEGE OF MEDICINE	1300 MORRIS PARK AVE	BRONX	NY	10461	BRONX	USA	Allergy and Infectious Diseases Research	007	13	2/22/2022	COMPETING CONTINUATION	$0
2022	2021	ALBERT EINSTEIN COLLEGE OF MEDICINE	1300 MORRIS PARK AVE	BRONX	NY	10461	BRONX	USA	Allergy and Infectious Diseases Research	002	13	1/12/2022	COMPETING CONTINUATION	$346,936
2022	2021	ALBERT EINSTEIN COLLEGE OF MEDICINE	1300 MORRIS PARK AVE	BRONX	NY	10461	BRONX	USA	Allergy and Infectious Diseases Research	006	13	2/18/2022	COMPETING CONTINUATION	$339,252
2022	2021	ALBERT EINSTEIN COLLEGE OF MEDICINE	1300 MORRIS PARK AVE	BRONX	NY	10461	BRONX	USA	Allergy and Infectious Diseases Research	004	13	2/10/2022	COMPETING CONTINUATION	-$346,936
2022	2021	ALBERT EINSTEIN COLLEGE OF MEDICINE	1300 MORRIS PARK AVE	BRONX	NY	10461	BRONX	USA	Allergy and Infectious Diseases Research	008	13	2/23/2022	COMPETING CONTINUATION	$0
2022	2021	ALBERT EINSTEIN COLLEGE OF MEDICINE	1300 MORRIS PARK AVE	BRONX	NY	10461	BRONX	USA	Allergy and Infectious Diseases Research	000	13	12/23/2021	COMPETING CONTINUATION	$0
2022	2020	ALBERT EINSTEIN COLLEGE OF MEDICINE	1300 MORRIS PARK AVE	BRONX	NY	10461	BRONX	USA	Allergy and Infectious Diseases Research	005	12	2/18/2022	NON-COMPETING CONTINUATION	-$339,252
2022	2020	ALBERT EINSTEIN COLLEGE OF MEDICINE	1300 MORRIS PARK AVE	BRONX	NY	10461	BRONX	USA	Allergy and Infectious Diseases Research	001	12	1/12/2022	NON-COMPETING CONTINUATION	-$346,936
2022	2020	ALBERT EINSTEIN COLLEGE OF MEDICINE	1300 MORRIS PARK AVE	BRONX	NY	10461	BRONX	USA	Allergy and Infectious Diseases Research	003	12	2/10/2022	NON-COMPETING CONTINUATION	$346,936
														Subtotal = $3,050,000

Issue Date FY: 2021 ( Subtotal = $2,900,000 )
2021	2021	ALBERT EINSTEIN COLLEGE OF MEDICINE	1300 MORRIS PARK AVE	BRONX	NY	10461	BRONX	USA	Allergy and Infectious Diseases Research	001	13	5/10/2021	COMPETING CONTINUATION	$2,900,000
2021	2020	ALBERT EINSTEIN COLLEGE OF MEDICINE	1300 MORRIS PARK AVE	BRONX	NY	10461	BRONX	USA	Allergy and Infectious Diseases Research	000	12	1/19/2021	NON-COMPETING CONTINUATION	$0
														Subtotal = $2,900,000

Grand Total All Awards = $35,974,939

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Central Africa International Epidemiology databases to Evaluate AIDS

Award Number: U01AI096299

ORGANIZATION: NATIONAL INSTITUTE OF ALLERGY & INFECTIOUS DISEASES

OPDIV: NIH

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 07/15/2011

PERIOD OF PERFORMANCE END DATE: 05/31/2028

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