Official websites use .gov

A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS

A lock ( 🔒 ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

Need Help

SWAN Genomic Analyses and SWAN Legacy

Award Number: U01AG017719
ORGANIZATION: NATIONAL INSTITUTE ON AGING
OPDIV: NIH
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 06/01/2000
PERIOD OF PERFORMANCE END DATE: 08/31/2022

Group Awards By:

View Award Description

SWAN Genomic Analyses and SWAN Legacy - DESCRIPTION (provided by applicant): The SWAN Repository is the portal to a singularly-unique body of specimens that are available to the scientific community for use in research studies of midlife and aging women. This competing renewal application provides for the continued maintenance of, and activities associated with, this important unique Repository of serum, plasma, urine, DNA and transformed cells as well as associated phenotypic data generated from the Study of Women's Health Across the Nation (SWAN). SWAN, recently renewed for its 5th funding cycle, is a cohort study of 3302 midlife women from 5 ethnic groups who have been evaluated prior to, during and following the menopausal transition. Participants have completed a total of 13 follow-up visits since 1996 with a final, late-postmenopausal visit planed for SWAN V. The SWAN Repository, a separately funded arm of SWAN, is designed to support, facilitate and extend the Core SWAN; to provide a mechanism for opening the resources of SWAN to the greater scientific community; and to support inclusion of SWAN in genomic science. This competing renewal provides first for the continued storage and management of the current ~1.7 million Repository specimens as well as for the additional specimens that will accrue as a result of fielding SWAN V in 2015-2016. It enables distribution of the specimens for new approved applications as well as of specimens required to address the aims of SWAN V, which capitalizes on Repository resources by conducting new science in these longitudinally collected specimens. Second, it will promote effective utilization of SWAN Repository specimens by enhancing the SWAN Data Warehouse (http://datawarehouse.swanrepository.com/), providing for administration of the application review process for specimen utilization and administrative management of specimen distribution to the broader scientific community including cost recovery programs and advertising Repository opportunities. Third, it will expand opportunities for incorporation of SWAN in on-going genetic consortia and facilitate genetic studies by performing dense genome-wide genotyping using the Illumina Infinium HumanOmni2.5plusExome BeadChip to measure genetic variants throughout the genome, including exome variants, in all SWAN participants who have provided DNA. Finally, it will implement the legacy SWAN Repository organizational structure to provide for ongoing effective and efficient utilization of SWAN data and specimens after the completion of SWAN V and in collaboration with the NIA. While the initial SWAN study design and questions were carefully deliberated, not all aspects of health and aging could be studied. New concepts and technologies have and will continue to emerge that should be employed to provide contemporary data and enhance knowledge of this critical life stage. The SWAN Repository makes this ongoing contribution to scientific knowledge possible.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2023 ( Subtotal = -$4,396 )
2023	2020	REGENTS OF THE UNIVERSITY OF MICHIGAN	1109 GEDDES AVE, SUITE 3300	ANN ARBOR	MI	48109	WASHTENAW	USA	Aging Research	000	20	9/13/2023	NON-COMPETING CONTINUATION	-$4,396
														Subtotal = -$4,396

Issue Date FY: 2022 ( Subtotal = $0 )
2022	2020	REGENTS OF THE UNIVERSITY OF MICHIGAN	503 THOMPSON ST	ANN ARBOR	MI	48109	WASHTENAW	USA	Aging Research	001	20	11/8/2021	NON-COMPETING CONTINUATION	$0
2022	2020	REGENTS OF THE UNIVERSITY OF MICHIGAN	503 THOMPSON ST	ANN ARBOR	MI	48109	WASHTENAW	USA	Aging Research	000	20	10/20/2021	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2021 ( Subtotal = $0 )
2021	2020	REGENTS OF THE UNIVERSITY OF MICHIGAN	503 THOMPSON ST	ANN ARBOR	MI	48109	WASHTENAW	USA	Aging Research	000	20	2/23/2021	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2020 ( Subtotal = $641,381 )
2020	2020	REGENTS OF THE UNIVERSITY OF MICHIGAN	503 THOMPSON ST	ANN ARBOR	MI	48109	WASHTENAW	USA	Aging Research	002	20	7/22/2020	NON-COMPETING CONTINUATION	$641,381
2020	2019	REGENTS OF THE UNIVERSITY OF MICHIGAN	503 THOMPSON ST	ANN ARBOR	MI	48109	WASHTENAW	USA	Aging Research	001	19	6/8/2020	NON-COMPETING CONTINUATION	$0
2020	2019	REGENTS OF THE UNIVERSITY OF MICHIGAN	503 THOMPSON ST	ANN ARBOR	MI	48109	WASHTENAW	USA	Aging Research	000	19	1/22/2020	NON-COMPETING CONTINUATION	$0
														Subtotal = $641,381

Issue Date FY: 2019 ( Subtotal = $707,272 )
2019	2019	REGENTS OF THE UNIVERSITY OF MICHIGAN	503 THOMPSON ST	ANN ARBOR	MI	48109	WASHTENAW	USA	Aging Research	001	19	8/5/2019	NON-COMPETING CONTINUATION	$707,272
2019	2018	REGENTS OF THE UNIVERSITY OF MICHIGAN	503 THOMPSON ST	ANN ARBOR	MI	48109	WASHTENAW	USA	Aging Research	000	18	11/23/2018	NON-COMPETING CONTINUATION	$0
														Subtotal = $707,272

Issue Date FY: 2018 ( Subtotal = $672,511 )
2018	2018	REGENTS OF THE UNIVERSITY OF MICHIGAN	503 THOMPSON ST	ANN ARBOR	MI	48109	WASHTENAW	USA	Aging Research	001	18	9/7/2018	NON-COMPETING CONTINUATION	$672,511
2018	2017	REGENTS OF THE UNIVERSITY OF MICHIGAN	503 THOMPSON ST	ANN ARBOR	MI	48109	WASHTENAW	USA	Aging Research	000	17	6/25/2018	NON-COMPETING CONTINUATION	$0
														Subtotal = $672,511

Issue Date FY: 2017 ( Subtotal = $1,604,008 )
2017	2017	REGENTS OF THE UNIVERSITY OF MICHIGAN	503 THOMPSON ST	ANN ARBOR	MI	48109	WASHTENAW	USA	Aging Research	002	17	7/21/2017	NON-COMPETING CONTINUATION	$1,604,008
2017	2016	REGENTS OF THE UNIVERSITY OF MICHIGAN	503 THOMPSON ST	ANN ARBOR	MI	48109	WASHTENAW	USA	Aging Research	000	16	1/14/2017	COMPETING CONTINUATION	$47,713
2017	2015	REGENTS OF THE UNIVERSITY OF MICHIGAN	503 THOMPSON ST	ANN ARBOR	MI	48109	WASHTENAW	USA	Aging Research	001	15	1/14/2017	SUPPLEMENT FOR EXPANSION	-$47,713
														Subtotal = $1,604,008

Issue Date FY: 2016 ( Subtotal = $1,112,400 )
2016	2016	UNIVERSITY OF MICHIGAN	3003 S STATE ST 3089 WOLVERINE	ANN ARBOR	MI	48109	WASHTENAW	USA	Aging Research	001	16	9/9/2016	COMPETING CONTINUATION	$1,112,400
2016	2014	Regents of the University of Michigan	3003 S STATE ST 3089 WOLVERINE	ANN ARBOR	MI	481091287	WASHTENAW	USA	Aging Research	000	15	7/11/2016	NON-COMPETING CONTINUATION	$0
														Subtotal = $1,112,400

Issue Date FY: 2015 ( Subtotal = $532,895 )
2015	2015	UNIVERSITY OF MICHIGAN	3003 S STATE ST 3089 WOLVERINE	ANN ARBOR	MI	48109	WASHTENAW	USA	Aging Research	000	15	7/22/2015	SUPPLEMENT FOR EXPANSION	$532,895
														Subtotal = $532,895

Issue Date FY: 2014 ( Subtotal = $662,096 )
2014	2014	UNIVERSITY OF MICHIGAN	3003 S STATE ST 3089 WOLVERINE	ANN ARBOR	MI	48109	WASHTENAW	USA	Aging Research	000	15	6/4/2014	NON-COMPETING CONTINUATION	$662,096
														Subtotal = $662,096

Issue Date FY: 2013 ( Subtotal = $1,087,088 )
2013	2013	UNIVERSITY OF MICHIGAN	3003 S STATE ST 3089 WOLVERINE	ANN ARBOR	MI	48109	WASHTENAW	USA	Aging Research	000	14	9/6/2013	NON-COMPETING CONTINUATION	$1,087,088
														Subtotal = $1,087,088

Issue Date FY: 2012 ( Subtotal = $1,184,863 )
2012	2012	UNIVERSITY OF MICHIGAN	3003 S STATE ST 3089 WOLVERINE	ANN ARBOR	MI	48109	WASHTENAW	USA	Aging Research	000	13	8/15/2012	NON-COMPETING CONTINUATION	$1,184,863
														Subtotal = $1,184,863

Issue Date FY: 2011 ( Subtotal = $1,937,413 )
2011	2011	UNIVERSITY OF MICHIGAN	3003 S STATE ST 3089 WOLVERINE	ANN ARBOR	MI	48109	WASHTENAW	USA	Aging Research	001	12	8/22/2011	NON-COMPETING CONTINUATION	$1,220,413
2011	2011	UNIVERSITY OF MICHIGAN	3003 S STATE ST 3089 WOLVERINE	ANN ARBOR	MI	48109	WASHTENAW	USA	Aging Research	002	12	9/22/2011	SUPPLEMENT FOR EXPANSION	$200,000
2011	2011	UNIVERSITY OF MICHIGAN	3003 S STATE ST 3089 WOLVERINE	ANN ARBOR	MI	48109	WASHTENAW	USA	Aging Research	000	11	6/22/2011	SUPPLEMENT FOR EXPANSION	$517,000
														Subtotal = $1,937,413

Issue Date FY: 2010 ( Subtotal = $852,722 )
2010	2010	UNIVERSITY OF MICHIGAN	3003 S STATE ST 3089 WOLVERINE	ANN ARBOR	MI	48109	WASHTENAW	USA	Aging Research	001	11	9/23/2010	COMPETING CONTINUATION	$852,722
2010	2009	UNIVERSITY OF MICHIGAN	3003 S STATE ST 3089 WOLVERINE	ANN ARBOR	MI	48109	WASHTENAW	USA	Aging Research	000	10	9/23/2010	NON-COMPETING CONTINUATION	$0
														Subtotal = $852,722

Issue Date FY: 2009 ( Subtotal = $861,431 )
2009	2009	UNIVERSITY OF MICHIGAN	3003 S STATE ST 3089 WOLVERINE	ANN ARBOR	MI	48109	WASHTENAW	USA	Aging Research	001	10	5/20/2009	NON-COMPETING CONTINUATION	$861,431
2009	2009	UNIVERSITY OF MICHIGAN	3003 S STATE ST 3089 WOLVERINE	ANN ARBOR	MI	48109	WASHTENAW	USA	Aging Research	002	10	9/9/2009	NON-COMPETING CONTINUATION	$0
2009	2008	UNIVERSITY OF MICHIGAN	3003 S STATE ST 3089 WOLVERINE	ANN ARBOR	MI	48109	WASHTENAW	USA	Aging Research	000	9	10/28/2008	NON-COMPETING CONTINUATION	$0
														Subtotal = $861,431

Issue Date FY: 2008 ( Subtotal = $915,703 )
2008	2008	UNIVERSITY OF MICHIGAN	3003 S STATE ST 3089 WOLVERINE	ANN ARBOR	MI	48109	WASHTENAW	USA	Aging Research	000	9	6/24/2008	NON-COMPETING CONTINUATION	$915,703
														Subtotal = $915,703

Issue Date FY: 2007 ( Subtotal = $1,191,464 )
2007	2007	UNIVERSITY OF MICHIGAN	3003 S STATE ST 3089 WOLVERINE	ANN ARBOR	MI	48109	WASHTENAW	USA	Aging Research	000	8	5/30/2007	NON-COMPETING CONTINUATION	$1,191,464
														Subtotal = $1,191,464

Issue Date FY: 2006 ( Subtotal = $1,182,154 )
2006	2006	UNIVERSITY OF MICHIGAN	3003 S STATE ST 3089 WOLVERINE	ANN ARBOR	MI	48109	WASHTENAW	USA	Aging Research	000	7	6/30/2006	NON-COMPETING CONTINUATION	$1,182,154
														Subtotal = $1,182,154

Issue Date FY: 2004 ( Subtotal = $1,792,756 ) (Continued on the next page)
Grand Total All Awards = $23,312,273

Page 1 of 2 (59 items)12

Top

All Categories

About

Search

Reports

Data Submission

Award Information

SWAN Genomic Analyses and SWAN Legacy

Award Number: U01AG017719

ORGANIZATION: NATIONAL INSTITUTE ON AGING

OPDIV: NIH

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 06/01/2000

PERIOD OF PERFORMANCE END DATE: 08/31/2022

Federal Websites

Department of Health & Human Services

HHS Operating Divisions

HHS Staff Divisions

Download A Document Viewer