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Assessment of Fetal Alcohol Spectrum Disorders (FASD) Using Novel Web-Based Tools

Award Number: U01AA014834
ORGANIZATION: NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM
OPDIV: NIH
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 09/30/2003
PERIOD OF PERFORMANCE END DATE: 04/30/2027

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Assessment of Fetal Alcohol Spectrum Disorders (FASD) Using Novel Web-Based Tools - The detrimental effects of prenatal alcohol exposure, including cognitive, behavioral, and physical impacts, have been well documented over several decades. They include long-standing effects on multiple domains of function. Alcohol-affected individuals often go unrecognized. In addition, wait times for evaluation can be quite long, further delaying the accurate identification of affected individuals. Effective online screening tools can decrease wait times and streamline evaluations in specialty clinics. Prenatal alcohol exposure continues to represent a significant public health concern and increased efforts at documenting risk, improving identification, and providing clinically-efficient tools are paramount. As such, the overarching aim of this proposal is to improve the screening for prenatal alcohol exposure and fetal alcohol spectrum disorder (FASD) by deploying web-based tools that aid in clinical evaluation. Two main tools will be used, the FASD-Tree and the Brief Assessment of Individual Neurobehavior – online version (BRAIN-online). Both tools use web-based technology for collecting data and provide the clinician with information about the individual’s physical, behavioral, and cognitive attributes. Specifically, the FASD-Tree records physical and behavioral data, and BRAIN-online measures impulsivity, attention, problem-solving, processing speed, memory, spatial working memory, and set-shifting. To achieve the aims of this study, child subjects (6-17y) will be evaluated using either the combination of FASD-Tree and BRAIN-online or BRAIN-online alone (Aim 1-3). Parents will complete online questionnaires regarding their child’s background, demographics, and behavior and some children will be given a standardized in-person neuropsychological test battery. In Aim 1, we will examine the relation between FASD-Tree and BRAIN-online, including classification accuracy, sensitivity, and specificity for each tool and their combination. In Aim 2, data from these novel tools will be combined with traditional and advanced (e.g., MorpheusQ and 3D facial imaging) physical measurements collected through other CIFASD projects. The combination of measures used in the proposed research will result in a convenient, scalable, and cost-effective adjunct to standard diagnostic tools.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $0 )
2025	2024	SAN DIEGO STATE UNIVERSITY FOUNDATION	5250 CAMPANILE DR	SAN DIEGO	CA	92182	SAN DIEGO	USA	Alcohol Research Programs	000	21	1/17/2025	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2024 ( Subtotal = $496,536 )
2024	2024	SAN DIEGO STATE UNIVERSITY FOUNDATION	5250 CAMPANILE DR	SAN DIEGO	CA	92182	SAN DIEGO	USA	Alcohol Research Programs	002	21	6/5/2024	SUPPLEMENT FOR EXPANSION	$54,313
2024	2024	SAN DIEGO STATE UNIVERSITY FOUNDATION	5250 CAMPANILE DR	SAN DIEGO	CA	92182	SAN DIEGO	USA	Alcohol Research Programs	001	21	5/9/2024	NON-COMPETING CONTINUATION	$442,223
2024	2023	SAN DIEGO STATE UNIVERSITY FOUNDATION	5250 CAMPANILE DR MC1947	SAN DIEGO	CA	92182	SAN DIEGO	USA	Alcohol Research Programs	000	20	12/13/2023	NON-COMPETING CONTINUATION	$0
														Subtotal = $496,536

Issue Date FY: 2023 ( Subtotal = $499,668 )
2023	2023	SAN DIEGO STATE UNIVERSITY FOUNDATION	5250 CAMPANILE DR MC1947	SAN DIEGO	CA	92182	SAN DIEGO	USA	Alcohol Research Programs	000	20	5/3/2023	NON-COMPETING CONTINUATION	$445,355
2023	2023	SAN DIEGO STATE UNIVERSITY FOUNDATION	5250 CAMPANILE DR MC1947	SAN DIEGO	CA	92182	SAN DIEGO	USA	Alcohol Research Programs	001	20	5/17/2023	SUPPLEMENT FOR EXPANSION	$54,313
2023	2022	SAN DIEGO STATE UNIVERSITY FOUNDATION	5250 CAMPANILE DR MC1947	SAN DIEGO	CA	92182	SAN DIEGO	USA	Alcohol Research Programs	004	19	5/31/2023	COMPETING CONTINUATION	$114,229
2023	2021	SAN DIEGO STATE UNIVERSITY FOUNDATION	5250 CAMPANILE DR MC1947	SAN DIEGO	CA	92182	SAN DIEGO	USA	Alcohol Research Programs	003	18	5/31/2023	SUPPLEMENT FOR EXPANSION	-$19,205
2023	2021	SAN DIEGO STATE UNIVERSITY FOUNDATION	5250 CAMPANILE DR MC1947	SAN DIEGO	CA	92182	SAN DIEGO	USA	Alcohol Research Programs	002	18	5/31/2023	NON-COMPETING CONTINUATION	-$95,023
														Subtotal = $499,668

Issue Date FY: 2022 ( Subtotal = $444,625 )
2022	2022	SAN DIEGO STATE UNIVERSITY FOUNDATION	5250 CAMPANILE DR MC1947	SAN DIEGO	CA	92182	SAN DIEGO	USA	Alcohol Research Programs	001	19	8/11/2022	COMPETING CONTINUATION	$444,625
2022	2021	SAN DIEGO STATE UNIVERSITY FOUNDATION	5250 CAMPANILE DR MC1947	SAN DIEGO	CA	92182	SAN DIEGO	USA	Alcohol Research Programs	000	18	8/11/2022	NON-COMPETING CONTINUATION	$0
														Subtotal = $444,625

Issue Date FY: 2021 ( Subtotal = $446,220 )
2021	2021	SAN DIEGO STATE UNIVERSITY FOUNDATION	5250 CAMPANILE DR MC1947	SAN DIEGO	CA	92182	SAN DIEGO	USA	Alcohol Research Programs	004	18	8/5/2021	NON-COMPETING CONTINUATION	$0
2021	2021	SAN DIEGO STATE UNIVERSITY FOUNDATION	5250 CAMPANILE DR MC1947	SAN DIEGO	CA	92182	SAN DIEGO	USA	Alcohol Research Programs	006	18	9/29/2021	SUPPLEMENT FOR EXPANSION	$0
2021	2021	SAN DIEGO STATE UNIVERSITY FOUNDATION	5250 CAMPANILE DR MC1947	SAN DIEGO	CA	92182	SAN DIEGO	USA	Alcohol Research Programs	002	18	7/23/2021	NON-COMPETING CONTINUATION	$371,197
2021	2021	SAN DIEGO STATE UNIVERSITY FOUNDATION	5250 CAMPANILE DR MC1947	SAN DIEGO	CA	92182	SAN DIEGO	USA	Alcohol Research Programs	005	18	9/29/2021	NON-COMPETING CONTINUATION	$0
2021	2021	SAN DIEGO STATE UNIVERSITY FOUNDATION	5250 CAMPANILE DR MC1947	SAN DIEGO	CA	92182	SAN DIEGO	USA	Alcohol Research Programs	003	18	7/27/2021	SUPPLEMENT FOR EXPANSION	$75,023
2021	2020	SAN DIEGO STATE UNIVERSITY FOUNDATION	5250 CAMPANILE DR MC1947	SAN DIEGO	CA	92182	SAN DIEGO	USA	Alcohol Research Programs	000	17	1/22/2021	NON-COMPETING CONTINUATION	$0
2021	2020	SAN DIEGO STATE UNIVERSITY FOUNDATION	5250 CAMPANILE DR MC1947	SAN DIEGO	CA	92182	SAN DIEGO	USA	Alcohol Research Programs	001	17	6/19/2021	NON-COMPETING CONTINUATION	$0
														Subtotal = $446,220

Issue Date FY: 2020 ( Subtotal = $484,566 )
2020	2020	SAN DIEGO STATE UNIVERSITY FOUNDATION	5250 CAMPANILE DR MC1947	SAN DIEGO	CA	92182	SAN DIEGO	USA	Alcohol Research Programs	001	16	1/23/2020	SUPPLEMENT FOR EXPANSION	$39,814
2020	2020	SAN DIEGO STATE UNIVERSITY FOUNDATION	5250 CAMPANILE DR MC1947	SAN DIEGO	CA	92182	SAN DIEGO	USA	Alcohol Research Programs	002	17	5/21/2020	NON-COMPETING CONTINUATION	$444,752
2020	2019	SAN DIEGO STATE UNIVERSITY FOUNDATION	5250 CAMPANILE DR MC1947	SAN DIEGO	CA	92182	SAN DIEGO	USA	Alcohol Research Programs	000	16	1/1/2020	NON-COMPETING CONTINUATION	$0
														Subtotal = $484,566

Issue Date FY: 2019 ( Subtotal = $581,714 )
2019	2019	SAN DIEGO STATE UNIVERSITY FOUNDATION	5250 CAMPANILE DR MC1947	SAN DIEGO	CA	92182	SAN DIEGO	USA	Alcohol Research Programs	001	15	5/15/2019	SUPPLEMENT FOR EXPANSION	$52,675
2019	2019	SAN DIEGO STATE UNIVERSITY FOUNDATION	5250 CAMPANILE DR MC1947	SAN DIEGO	CA	92182	SAN DIEGO	USA	Alcohol Research Programs	002	16	6/3/2019	NON-COMPETING CONTINUATION	$529,039
2019	2018	SAN DIEGO STATE UNIVERSITY FOUNDATION	5250 CAMPANILE DR MC1947	SAN DIEGO	CA	92182	SAN DIEGO	USA	Alcohol Research Programs	000	15	2/7/2019	NON-COMPETING CONTINUATION	$0
														Subtotal = $581,714

Issue Date FY: 2018 ( Subtotal = $361,787 )
2018	2018	SAN DIEGO STATE UNIVERSITY FOUNDATION	5250 CAMPANILE DR MC1947	SAN DIEGO	CA	92182	SAN DIEGO	USA	Alcohol Research Programs	002	15	5/16/2018	NON-COMPETING CONTINUATION	$361,787
2018	2017	SAN DIEGO STATE UNIVERSITY FOUNDATION	5250 CAMPANILE DR MC1947	SAN DIEGO	CA	92182	SAN DIEGO	USA	Alcohol Research Programs	001	14	10/16/2017	COMPETING CONTINUATION	$242,544
2018	2016	SAN DIEGO STATE UNIVERSITY FOUNDATION	5250 CAMPANILE DR MC1947	SAN DIEGO	CA	92182	SAN DIEGO	USA	Alcohol Research Programs	000	13	10/16/2017	EXTENSION WITH OR WITHOUT FUNDS	-$242,544
														Subtotal = $361,787

Issue Date FY: 2017 ( Subtotal = $379,702 )
2017	2017	SAN DIEGO STATE UNIVERSITY FOUNDATION	5250 CAMPANILE DR MC1947	SAN DIEGO	CA	92182	SAN DIEGO	USA	Alcohol Research Programs	002	14	7/6/2017	COMPETING CONTINUATION	$379,702
2017	2016	SAN DIEGO STATE UNIVERSITY FOUNDATION	5250 CAMPANILE DR MC1947	SAN DIEGO	CA	92182	SAN DIEGO	USA	Alcohol Research Programs	001	13	12/2/2016	EXTENSION WITH OR WITHOUT FUNDS	$155,136
2017	2015	SAN DIEGO STATE UNIVERSITY FOUNDATION	5250 CAMPANILE DR MC1947	SAN DIEGO	CA	92182	SAN DIEGO	USA	Alcohol Research Programs	000	12	12/2/2016	NON-COMPETING CONTINUATION	-$155,136
														Subtotal = $379,702

Issue Date FY: 2016 ( Subtotal = $612,055 )
2016	2016	SAN DIEGO STATE UNIVERSITY, FOUNDATION	SAN DIEGO STATE UNIVERSITY	SAN DIEGO	CA	92182	SAN DIEGO	USA	Alcohol Research Programs	000	13	5/13/2016	EXTENSION WITH OR WITHOUT FUNDS	$612,055
														Subtotal = $612,055

Issue Date FY: 2015 ( Subtotal = $572,076 )
2015	2015	SAN DIEGO STATE UNIVERSITY, FOUNDATION	SAN DIEGO STATE UNIVERSITY	SAN DIEGO	CA	92182	SAN DIEGO	USA	Alcohol Research Programs	000	12	5/4/2015	NON-COMPETING CONTINUATION	$572,076
														Subtotal = $572,076

Issue Date FY: 2014 ( Subtotal = $572,170 )
2014	2014	SAN DIEGO STATE UNIVERSITY, FOUNDATION	SAN DIEGO STATE UNIVERSITY	SAN DIEGO	CA	92182	SAN DIEGO	USA	Alcohol Research Programs	000	11	5/29/2014	NON-COMPETING CONTINUATION	$572,170
														Subtotal = $572,170

Issue Date FY: 2013 ( Subtotal = $548,566 )
2013	2013	SAN DIEGO STATE UNIVERSITY, FOUNDATION	SAN DIEGO STATE UNIVERSITY	SAN DIEGO	CA	92182	SAN DIEGO	USA	Alcohol Research Programs	000	10	5/31/2013	NON-COMPETING CONTINUATION	$548,566
														Subtotal = $548,566

Issue Date FY: 2012 ( Subtotal = $542,926 )
2012	2012	SAN DIEGO STATE UNIVERSITY, FOUNDATION	SAN DIEGO STATE UNIVERSITY	SAN DIEGO	CA	92182	SAN DIEGO	USA	Alcohol Research Programs	000	9	8/9/2012	COMPETING CONTINUATION	$542,926
														Subtotal = $542,926

Issue Date FY: 2011 ( Subtotal = $682,793 ) (Continued on the next page)
Grand Total All Awards = $11,082,710

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Assessment of Fetal Alcohol Spectrum Disorders (FASD) Using Novel Web-Based Tools

Award Number: U01AA014834

ORGANIZATION: NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM

OPDIV: NIH

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 09/30/2003

PERIOD OF PERFORMANCE END DATE: 04/30/2027

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