Sunday, July 20, 2025 7/20/2025

Yes & Know!: A Rigorous Evaluation of a Fully Digital Intervention Integrating Group-based Education with Digital Tools to Improve Youth Sexual Health and Well-Being

Award Number: TP2AH000079
ORGANIZATION: OFFICE OF ADOLESCENT HEALTH
OPDIV: DHHS/OS
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: DEMONSTRATION
PERIOD OF PERFORMANCE START DATE: 09/15/2023
PERIOD OF PERFORMANCE END DATE: 09/14/2028

Group Awards By:

View Award Description

Yes & Know!: A Rigorous Evaluation of a Fully Digital Intervention Integrating Group-based Education with Digital Tools to Improve Youth Sexual Health and Well-Being - ETR, along with our evaluation partner University of California San Francisco (UCSF), propose the rigorous evaluation of Yes & Know!, a fully virtual intervention that integrates group-based education with digital tools to support young people ages 14-19 by increasing their relationship and healthy life skills with the goal of reducing unintended pregnancy and sexually transmitted infections (STIs). The evaluation will test the efficacy of Yes & Know! among youth living in rural communities across the U.S. This intervention is a digital and enhanced adaptation of an in-person, adolescent sexual health education program that was co-designed with youth and evaluated in community-based organizations and schools in Fresno County, California from 2017-20201. Building on findings from the original intervention and scientific evidence, the primary aim of Yes & Know! supports skills related to adolescents’ positive health and well-being and provides necessary and timely information and resources to reduce unprotected vaginal or anal sex. The evaluation will be led by UCSF. Using a cluster randomized controlled trial, we will compare the short-term (3-month post-intervention), and long-term (12-month post-intervention) outcomes of the Yes & Know! program relative to standard of care on youth aged 14-19 years, with a focus on youth in rural areas. The study will seek to answer the primary and secondary research questions: (Primary) Twelve months following the end of the program, what is the impact of Yes & Know! on the prevalence of unprotected vaginal or anal sex in the past 3 months? (Secondary) Three months following the end of the program, what is the impact of Yes & Know! relative to standard of care on composite scores of reproductive health knowledge? (Secondary) Three months following the end of the program, what is the impact of Yes & Know! relative to standard of care on compositive scores of healthy relationships knowledge? (Secondary) Three months following the end of the program, what is the impact of Yes & Know! relative to standard of care on self-efficacy to refuse unwanted sex? (Secondary) Three months following the end of the program, what is the impact of Yes & Know! relative to standard of care on self-efficacy to cope with stress? (Secondary) Twelve months following the end of the program, what is the impact of Yes & Know! relative to standard of care on use of sexual and reproductive health services in the past 3 months? This study has the potential to add to the paucity of literature about the feasibility and efficacy of technology based sexual health programs, particularly self-paced, asynchronous learning supported by technology. This new modality for implementation has the potential to profoundly transform future program development and address inequities by extending the reach to youth who are missed by traditional in-person, school-based programming. The study will also add to the literature on programs for rural populations, with the potential to reduce persistent geographic disparities in unintended pregnancy and STIs. In addition, it will specifically measure changes in use of sexual health services and youth mental health and resilience, areas which are under evaluated in evidence-based program research.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $0 )
2025	2024	EDUCATION TRAINING & RESEARCH ASSOCIATES	5619 SCOTTS VALLEY DR	SCOTTS VALLEY	CA	95066	SANTA CRUZ	USA	Teenage Pregnancy Prevention Program	01	2	2/7/2025	ADMINISTRATIVE SUPPLEMENT ( + OR - ) (DISCRETIONARY OR BLOCK AWARDS)	$0
2025	2023	EDUCATION TRAINING & RESEARCH ASSOCIATES	5619 SCOTTS VALLEY DR	SCOTTS VALLEY	CA	95066	SANTA CRUZ	USA	Teenage Pregnancy Prevention Program	01	2	2/7/2025	ADMINISTRATIVE SUPPLEMENT ( + OR - ) (DISCRETIONARY OR BLOCK AWARDS)	$0
														Subtotal = $0

Issue Date FY: 2024 ( Subtotal = $1,000,000 )
2024	2024	EDUCATION TRAINING & RESEARCH ASSOCIATES	5619 SCOTTS VALLEY DR	SCOTTS VALLEY	CA	95066	SANTA CRUZ	USA	Teenage Pregnancy Prevention Program	00	2	8/27/2024	NON-COMPETING CONTINUATION	$1,000,000
2024	2023	EDUCATION TRAINING & RESEARCH ASSOCIATES	5619 SCOTTS VALLEY DR	SCOTTS VALLEY	CA	95066	SANTA CRUZ	USA	Teenage Pregnancy Prevention Program	00	2	8/27/2024	NON-COMPETING CONTINUATION	$0
														Subtotal = $1,000,000

Issue Date FY: 2023 ( Subtotal = $1,000,000 )
2023	2023	Education, Training, and Research Associates	5619 SCOTTS VALLEY DR STE 140	SCOTTS VALLEY	CA	95066	SANTA CRUZ	USA	Teenage Pregnancy Prevention Program	01	1	9/25/2023	ADMINISTRATIVE SUPPLEMENT ( + OR - ) (DISCRETIONARY OR BLOCK AWARDS)	$0
2023	2023	EDUCATION, TRAINING, AND RESEARCH ASSOCIATES	5619 SCOTTS VALLEY DR STE 140	SCOTTS VALLEY	CA	95066	SANTA CRUZ	USA	Teenage Pregnancy Prevention Program	00	1	8/18/2023	NEW	$1,000,000
														Subtotal = $1,000,000

Grand Total All Awards = $2,000,000

Top

All Categories

About

Search

Reports

Data Submission

Award Information

Yes & Know!: A Rigorous Evaluation of a Fully Digital Intervention Integrating Group-based Education with Digital Tools to Improve Youth Sexual Health and Well-Being

Award Number: TP2AH000079

ORGANIZATION: OFFICE OF ADOLESCENT HEALTH

OPDIV: DHHS/OS

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: DEMONSTRATION

PERIOD OF PERFORMANCE START DATE: 09/15/2023

PERIOD OF PERFORMANCE END DATE: 09/14/2028

Federal Websites

Department of Health & Human Services

HHS Operating Divisions

HHS Staff Divisions

Download A Document Viewer