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NRSA Training Core

Award Number: TL1TR001997
ORGANIZATION: NATIONAL CENTER FOR ADVANCING TRANSLATIONAL SCIENCES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP
PERIOD OF PERFORMANCE START DATE: 08/15/2016
PERIOD OF PERFORMANCE END DATE: 06/30/2026

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NRSA Training Core - PROJECT SUMMARY – TL1 TRAINING PROGRAM The University of Kentucky (UK) Center for Clinical and Translational Science (CCTS) proposes to sustain and enhance the current pre-doctoral and post-doctoral TL1 program, currently in its ninth year of National Institutes of Health (NIH) support. By providing a multidisciplinary training program that integrates trainees across diverse fields and offers rigorous and solid translational research education, the TL1 program has effectively prepared clinicians- and scientists-in-training for careers as leaders in clinical and translational science. The UK TL1 program features substantial collaborations across a robust cohort of productive investigators, a talented pool of qualified applicants, solid infrastructure and strong institutional support. The program takes advantage of the physical juxtaposition of UK’s six health care colleges (Medicine, Nursing, Pharmacy, Public Health, Health Sciences, Dentistry) and key disciplines on the main campus (e.g. Engineering, Social Work, Biology, Psychology, Education) to train scholars across wide-ranging fields necessary for successful clinical and translational research (CTR). The program supports career development of scholars with research interests that cross the lifespan (prenatal through elderly) and the full spectrum of clinical and translational science, including translational, clinical, community/policy studies and CTR methods/processes (e.g., biomedical informatics) focusing on a broad array of health topics. The TL1 trainees are making important contributions to science through published work, and all of the program graduates are actively engaged in CTR. This program and other CCTS-sponsored efforts are engaging underserved students in projects focused on health disparities of Kentucky and the Central Appalachian area. We are requesting renewed NIH support for eight TL1 scholars. The foundation of the proposed program will continue to be practical research experiences within multidisciplinary teams guided by experienced mentors along with educational and training offerings, such as certificate, Master’s and PhD degrees, to ensure successful career development of these future CTR leaders. Scholar competency assessments, based on the Clinical Research Appraisal Inventory, serve to guide new program offerings with the theory that trainees who have high confidence in their skills are more likely to pursue a career in CTR. UK CCTS-developed pipeline programs targeting professional and graduate students, including new initiatives to support health equities researchers and trainees from under-represented groups, will ensure the availability of a strong pool of candidates for the TL1 program. In sum, the TL1 program is designed to accelerate career development of future leaders in the translational science workforce who will be prepared to address today’s complex research challenges and spearhead advances in human health. Project Summary/Abstract


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $0 )
2025	2024	UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION, THE	500 S LIMESTONE	LEXINGTON	KY	40526	FAYETTE	USA	National Center for Advancing Translational Sciences	000	8	12/13/2024	NON-COMPETING CONTINUATION	$0
2025	2024	UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION, THE	500 S LIMESTONE	LEXINGTON	KY	40526	FAYETTE	USA	National Center for Advancing Translational Sciences	001	8	5/1/2025	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2024 ( Subtotal = $454,334 )
2024	2024	UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION, THE	500 S LIMESTONE	LEXINGTON	KY	40526	FAYETTE	USA	National Center for Advancing Translational Sciences	000	8	6/17/2024	NON-COMPETING CONTINUATION	$486,219
2024	2024	UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION, THE	500 S LIMESTONE	LEXINGTON	KY	40526	FAYETTE	USA	National Center for Advancing Translational Sciences	002	8	8/16/2024	NON-COMPETING CONTINUATION	$0
2024	2023	UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION, THE	500 S LIMESTONE	LEXINGTON	KY	40526	FAYETTE	USA	National Center for Advancing Translational Sciences	001	7	6/18/2024	NON-COMPETING CONTINUATION	-$31,885
														Subtotal = $454,334

Issue Date FY: 2023 ( Subtotal = $501,897 )
2023	2023	UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION, THE	500 S LIMESTONE 109 KINKEAD HALL	LEXINGTON	KY	40526	FAYETTE	USA	National Center for Advancing Translational Sciences	000	7	6/23/2023	NON-COMPETING CONTINUATION	$534,287
2023	2023	UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION, THE	500 S LIMESTONE 109 KINKEAD HALL	LEXINGTON	KY	40526	FAYETTE	USA	National Center for Advancing Translational Sciences	001	7	8/18/2023	NON-COMPETING CONTINUATION	-$32,390
														Subtotal = $501,897

Issue Date FY: 2022 ( Subtotal = $41,492 )
2022	2022	UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION, THE	500 S LIMESTONE 109 KINKEAD HALL	LEXINGTON	KY	40526	FAYETTE	USA	National Center for Advancing Translational Sciences	000	6	7/25/2022	NON-COMPETING CONTINUATION	$41,492
														Subtotal = $41,492

Issue Date FY: 2021 ( Subtotal = $463,055 )
2021	2021	UNIVERSITY OF KENTUCKY	500 S LIMESTONE 109 KINKEAD HALL	LEXINGTON	KY	40526	FAYETTE	USA	National Center for Advancing Translational Sciences	000	5	7/30/2021	COMPETING CONTINUATION	$463,055
2021	2021	UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION, THE	500 S LIMESTONE 109 KINKEAD HALL	LEXINGTON	KY	40526	FAYETTE	USA	National Center for Advancing Translational Sciences	002	5	9/19/2021	COMPETING CONTINUATION	$448,958
2021	2019	UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION, THE	500 S LIMESTONE 109 KINKEAD HALL	LEXINGTON	KY	40526	FAYETTE	USA	National Center for Advancing Translational Sciences	001	4	9/19/2021	NON-COMPETING CONTINUATION	-$448,958
														Subtotal = $463,055

Issue Date FY: 2019 ( Subtotal = $570,836 )
2019	2019	UNIVERSITY OF KENTUCKY	500 S LIMESTONE 109 KINKEAD HALL	LEXINGTON	KY	40526	FAYETTE	USA	National Center for Advancing Translational Sciences	000	4	7/2/2019	NON-COMPETING CONTINUATION	$570,836
														Subtotal = $570,836

Issue Date FY: 2018 ( Subtotal = $558,783 )
2018	2018	UNIVERSITY OF KENTUCKY	500 S LIMESTONE 109 KINKEAD HALL	LEXINGTON	KY	40526	FAYETTE	USA	National Center for Advancing Translational Sciences	000	3	6/5/2018	NON-COMPETING CONTINUATION	$558,783
														Subtotal = $558,783

Issue Date FY: 2017 ( Subtotal = $548,415 )
2017	2017	UNIVERSITY OF KENTUCKY	500 S LIMESTONE 109 KINKEAD HALL	LEXINGTON	KY	40526	FAYETTE	USA	National Center for Advancing Translational Sciences	001	2	7/13/2017	NON-COMPETING CONTINUATION	$3,538
2017	2017	UNIVERSITY OF KENTUCKY	500 S LIMESTONE 109 KINKEAD HALL	LEXINGTON	KY	40526	FAYETTE	USA	National Center for Advancing Translational Sciences	000	2	6/19/2017	NON-COMPETING CONTINUATION	$544,877
														Subtotal = $548,415

Issue Date FY: 2016 ( Subtotal = $541,417 )
2016	2016	UNIVERSITY OF KENTUCKY, RESEARCH FOUNDATION	109 KINEAD HALL	LEXINGTON	KY	40506	FAYETTE	USA	National Center for Advancing Translational Sciences	000	1	8/15/2016	NEW	$541,417
														Subtotal = $541,417

Grand Total All Awards = $3,680,229

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NRSA Training Core

Award Number: TL1TR001997

ORGANIZATION: NATIONAL CENTER FOR ADVANCING TRANSLATIONAL SCIENCES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP

PERIOD OF PERFORMANCE START DATE: 08/15/2016

PERIOD OF PERFORMANCE END DATE: 06/30/2026

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