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Training the next generation of clinical neuroscientists

Award Number: T32MH122394
ORGANIZATION: NATIONAL INSTITUTE OF MENTAL HEALTH
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP
PERIOD OF PERFORMANCE START DATE: 07/01/2020
PERIOD OF PERFORMANCE END DATE: 06/30/2030

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Training the next generation of clinical neuroscientists - Modified Project Summary/Abstract Section This renewal proposal requests support for years 6-10 of the T32MH122394 program “Training the next generation of clinical neuroscientists”, founded in 2020. We plan to continue to recruit 2 new postdoctoral fellows per year, and reappoint 3 trainees each year, for a total of 5 postdoctoral slots per year, as we have been doing since year 3 of the T32. Trainees are supported for 2-3 years, contingent on Steering Committee evaluation of their progress prior to competitive applications for reappointment for Year 3. Our T32 is led by Dr. René Kahn, MD, PhD, a renowned physician-scientist with an outstanding track record as an investigator and mentor in the field of neuroimaging and treatment of schizophrenia and bipolar disorder, and multiple PIs Dr. Antonia New, MD, and Dr. Mercedes Perez, MD, PhD, both physician-scientists with extensive mentorship and research experience. Mount Sinai is the ideal place for this T32 program because of the strength of our Departments of Psychiatry, Neuroscience and Genetics/Genomics, which have been among the top 10 departments nationwide in NIH funding over the past 5 years, and have a wealth of mentors. There is a focused institutional effort to support clinician-scientists and translational research. Psychiatry is a fertile medical specialty for translational research and clinician-scientists bring a unique perspective to research through the blend of clinical and research experiences. They are uniquely poised to bridge the gap between basic neurobiology and clinical disease and excel as leaders in translational research in psychiatry. Our T32 program aims to train clinician-scientists who will be able to combine clinical knowledge and expertise with superior research in psychiatry and neuroscience. One key goal is to increase the pool of physician-scientists, as there is high attrition after completion of clinical residency training. Our T32 program aims to address this by helping trainees acquire research skills and pilot data to obtain a career development (K) award. Our program will provide research protected time and coursework organized based on an Individual Development Plan. This training, coupled with outstanding mentoring, networking opportunities, grant writing seminars and an internal K award review process, will prepare promising clinician scientists and help accelerate the launch of productive, independent careers in translational psychiatry research. For this renewal, we have strengthened our curriculum in translational neuroscience by adding a track in AI, Natural Language Processing and Computational Psychiatry. In the 4 years since its creation, 8 fellows have been appointed to our T32 program and 4 have graduated. Our program has been highly successful in achieving the goals as shown by the following metrics: 1) high rates of trainee success (100%, 4/4) in obtaining faculty appointments, external grant funding, or other research-focused positions; 2) high number, quality and impact of trainee publications (mean publications=49; mean h-index=20); 3) highly qualified trainees including clinician-scientists and physicians.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = $372,409 )
2026	2026	ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI	1 GUSTAVE L LEVY PL	NEW YORK	NY	10029	NEW YORK	USA	Mental Health Research Grants	001	7	5/13/2026	NON-COMPETING CONTINUATION	$372,409
2026	2024	ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI	1 GUSTAVE L LEVY PL	NEW YORK	NY	10029	NEW YORK	USA	Mental Health Research Grants	000	5	12/17/2025	NON-COMPETING CONTINUATION	$0
														Subtotal = $372,409

Issue Date FY: 2025 ( Subtotal = $391,828 )
2025	2025	ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI	1 GUSTAVE L LEVY PL	NEW YORK	NY	10029	NEW YORK	USA	Mental Health Research Grants	000	6	7/1/2025	COMPETING CONTINUATION	$391,828
														Subtotal = $391,828

Issue Date FY: 2024 ( Subtotal = $405,897 )
2024	2024	ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI	1 GUSTAVE L LEVY PL	NEW YORK	NY	10029	NEW YORK	USA	Mental Health Research Grants	001	5	8/29/2024	NON-COMPETING CONTINUATION	$405,897
2024	2023	ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI	1 GUSTAVE L LEVY PL	NEW YORK	NY	10029	NEW YORK	USA	Mental Health Research Grants	000	4	8/28/2024	NON-COMPETING CONTINUATION	$0
														Subtotal = $405,897

Issue Date FY: 2023 ( Subtotal = $422,233 )
2023	2023	ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI	ONE GUSTAVE L LEVY PL	NEW YORK	NY	10029	NEW YORK	USA	Mental Health Research Grants	000	4	6/28/2023	NON-COMPETING CONTINUATION	$422,233
														Subtotal = $422,233

Issue Date FY: 2022 ( Subtotal = $429,011 )
2022	2022	ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI	ONE GUSTAVE L LEVY PL	NEW YORK	NY	10029	NEW YORK	USA	Mental Health Research Grants	000	3	6/17/2022	NON-COMPETING CONTINUATION	$429,011
														Subtotal = $429,011

Issue Date FY: 2021 ( Subtotal = $348,408 )
2021	2021	ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI	ONE GUSTAVE L LEVY PL	NEW YORK	NY	10029	NEW YORK	USA	Mental Health Research Grants	000	2	4/9/2021	NON-COMPETING CONTINUATION	$348,408
														Subtotal = $348,408

Issue Date FY: 2020 ( Subtotal = $170,303 )
2020	2020	ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI	ONE GUSTAVE L LEVY PL	NEW YORK	NY	10029	NEW YORK	USA	Mental Health Research Grants	001	1	4/28/2020	NEW	$0
2020	2020	ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI	ONE GUSTAVE L LEVY PL	NEW YORK	NY	10029	NEW YORK	USA	Mental Health Research Grants	000	1	4/20/2020	NEW	$170,303
														Subtotal = $170,303

Grand Total All Awards = $2,540,089

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Training the next generation of clinical neuroscientists

Award Number: T32MH122394

ORGANIZATION: NATIONAL INSTITUTE OF MENTAL HEALTH

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP

PERIOD OF PERFORMANCE START DATE: 07/01/2020

PERIOD OF PERFORMANCE END DATE: 06/30/2030

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