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Molecular and Cellular Basis of Cardiovascular Disease

Award Number: T32HL007731
ORGANIZATION: NATIONAL HEART, LUNG, & BLOOD INSTITUTE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP
PERIOD OF PERFORMANCE START DATE: 07/01/1992
PERIOD OF PERFORMANCE END DATE: 05/31/2029

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Molecular and Cellular Basis of Cardiovascular Disease - SUMMARY / ABSTRACT Cardiovascular diseases remain the leading cause of death in the United States and worldwide and are a significant cause of premature death, disability, and loss of quality-of-life. Novel technologies and approaches to determine the mechanisms that cause or contribute to cardiovascular diseases have become increasingly powerful, but these approaches have also become increasingly specialized. Multidisciplinary efforts that bring together investigators with complementary knowledge, tools and skills and integrate laboratory and patient-based research are essential for ongoing efforts to leverage information about mechanisms of disease into rationale therapeutic approaches for treatment. Thus, the need for broadly trained scientists who can adopt innovative technologies, assemble tools from different disciplines, and bridge basic, translational, and clinical science is greater than ever. The overall goal of the UCSF Training Program in the Molecular and Cellular Basis of Cardiovascular Disease is to train a diverse group of investigators who will be at the forefront of cardiovascular discovery and disease research. Toward this goal, this training program will: 1) attract talented PhD-trained postdoctoral scientists from a broad national and international applicant pool and from an outstanding group of MD- and MD/PhD-trained researchers from UCSF's Cardiology and other clinical fellowships to postdoctoral training in cardiovascular research; and 2) leverage the strong multidisciplinary research environment in UCSF’s Cardiovascular Research Institute (CVRI) to provide outstanding scientific training in the context of research programs focused on cardiovascular biology and disease. The Program brings together a diverse and outstanding group of mentors with a common interest in cardiovascular biology and a commitment to mentorship and training of a diverse group of postdoctoral scientists. The heart of this training program is formulation and execution of a substantial research project relevant to cardiovascular biology and development of professional skills under the guidance of a faculty mentor. The Training Program includes state-of-the-art, cutting edge research opportunities in laboratories that span basic, translational, and patient-based, clinical research. Program trainees benefit from the cohesive, multidisciplinary training environment in CVRI, and the robust intellectual and scientific environment in the CVRI and at UCSF more generally. Trainees also benefit from co-mentoring, peer-mentoring, ready access to collaborators and colleagues with overlapping but complementary interests and expertise, and extensive and robust didactic training in the Responsible Conduct of Research, Training in Clinical Research, if appropriate, and a strong emphasis on reproducibility and rigor in scientific examination.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $661,071 )
2025	2025	REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, THE	1855 FOLSOM ST STE 425	SAN FRANCISCO	CA	94103	SAN FRANCISCO	USA	Cardiovascular Diseases Research	001	32	8/5/2025	NON-COMPETING CONTINUATION	$661,071
2025	2022	REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, THE	1855 FOLSOM ST STE 425	SAN FRANCISCO	CA	94103	SAN FRANCISCO	USA	Cardiovascular Diseases Research	000	30	1/22/2025	NON-COMPETING CONTINUATION	$0
														Subtotal = $661,071

Issue Date FY: 2024 ( Subtotal = $730,211 )
2024	2024	REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, THE	1855 FOLSOM ST STE 425	SAN FRANCISCO	CA	94103	SAN FRANCISCO	USA	Cardiovascular Diseases Research	001	31	7/27/2024	COMPETING CONTINUATION	$48,146
2024	2024	REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, THE	1855 FOLSOM ST STE 425	SAN FRANCISCO	CA	94103	SAN FRANCISCO	USA	Cardiovascular Diseases Research	000	31	3/26/2024	COMPETING CONTINUATION	$682,065
														Subtotal = $730,211

Issue Date FY: 2022 ( Subtotal = $423,931 )
2022	2022	REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, THE	1855 FOLSOM ST STE 425	SAN FRANCISCO	CA	94143	SAN FRANCISCO	USA	Cardiovascular Diseases Research	000	30	6/6/2022	NON-COMPETING CONTINUATION	$412,997
2022	2022	REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, THE	1855 FOLSOM ST STE 425	SAN FRANCISCO	CA	94143	SAN FRANCISCO	USA	Cardiovascular Diseases Research	001	30	6/10/2022	NON-COMPETING CONTINUATION	$10,934
														Subtotal = $423,931

Issue Date FY: 2021 ( Subtotal = $654,974 )
2021	2021	REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, THE	1855 FOLSOM ST STE 425	SAN FRANCISCO	CA	94143	SAN FRANCISCO	USA	Cardiovascular Diseases Research	001	29	5/31/2021	NON-COMPETING CONTINUATION	$654,974
2021	2020	REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, THE	1855 FOLSOM ST STE 425	SAN FRANCISCO	CA	94143	SAN FRANCISCO	USA	Cardiovascular Diseases Research	000	28	11/4/2020	NON-COMPETING CONTINUATION	$0
														Subtotal = $654,974

Issue Date FY: 2020 ( Subtotal = $645,008 )
2020	2020	REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, THE	1855 FOLSOM ST STE 425	SAN FRANCISCO	CA	94143	SAN FRANCISCO	USA	Cardiovascular Diseases Research	000	28	6/19/2020	NON-COMPETING CONTINUATION	$645,008
														Subtotal = $645,008

Issue Date FY: 2019 ( Subtotal = $613,040 )
2019	2019	REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, THE	1855 FOLSOM ST STE 425	SAN FRANCISCO	CA	94143	SAN FRANCISCO	USA	Cardiovascular Diseases Research	000	27	5/25/2019	NON-COMPETING CONTINUATION	$613,040
2019	2018	REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, THE	1855 FOLSOM ST STE 425	SAN FRANCISCO	CA	94143	SAN FRANCISCO	USA	Cardiovascular Diseases Research	001	26	6/28/2019	COMPETING CONTINUATION	$0
														Subtotal = $613,040

Issue Date FY: 2018 ( Subtotal = $590,818 )
2018	2018	REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, THE	1855 FOLSOM ST STE 425	SAN FRANCISCO	CA	94143	SAN FRANCISCO	USA	Cardiovascular Diseases Research	004	26	9/14/2018	COMPETING CONTINUATION	$214,586
2018	2018	REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, THE	1855 FOLSOM ST STE 420	SAN FRANCISCO	CA	94103	SAN FRANCISCO	USA	Cardiovascular Diseases Research	001	26	1/3/2018	COMPETING CONTINUATION	$573,209
2018	2018	REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, THE	1855 FOLSOM ST STE 420	SAN FRANCISCO	CA	94103	SAN FRANCISCO	USA	Cardiovascular Diseases Research	002	26	8/2/2018	COMPETING CONTINUATION	$17,609
2018	2016	REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, THE	1855 FOLSOM ST STE 425	SAN FRANCISCO	CA	94143	SAN FRANCISCO	USA	Cardiovascular Diseases Research	003	25	9/14/2018	EXTENSION WITH OR WITHOUT FUNDS	-$214,586
2018	2016	REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, THE	1855 FOLSOM ST STE 420	SAN FRANCISCO	CA	94103	SAN FRANCISCO	USA	Cardiovascular Diseases Research	000	25	1/2/2018	EXTENSION WITH OR WITHOUT FUNDS	$0
														Subtotal = $590,818

Issue Date FY: 2017 ( Subtotal = $0 )
2017	2016	REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, THE	1855 FOLSOM ST STE 420	SAN FRANCISCO	CA	94103	SAN FRANCISCO	USA	Cardiovascular Diseases Research	002	25	1/9/2017	EXTENSION WITH OR WITHOUT FUNDS	$707,910
2017	2015	REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, THE	1855 FOLSOM ST STE 420	SAN FRANCISCO	CA	94103	SAN FRANCISCO	USA	Cardiovascular Diseases Research	001	24	1/9/2017	NON-COMPETING CONTINUATION	-$551,182
2017	2014	REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, THE	1855 FOLSOM ST STE 420	SAN FRANCISCO	CA	94103	SAN FRANCISCO	USA	Cardiovascular Diseases Research	000	23	1/9/2017	NON-COMPETING CONTINUATION	-$156,728
														Subtotal = $0

Issue Date FY: 2016 ( Subtotal = $352,169 )
2016	2016	UNIVERSITY OF CALIFORNIA-SAN FRANCISCO	BOX 0812	SAN FRANCISCO	CA	94143	SAN FRANCISCO	USA	Cardiovascular Diseases Research	000	25	7/29/2016	EXTENSION WITH OR WITHOUT FUNDS	$352,169
														Subtotal = $352,169

Issue Date FY: 2015 ( Subtotal = $551,182 )
2015	2015	UNIVERSITY OF CALIFORNIA-SAN FRANCISCO	BOX 0812	SAN FRANCISCO	CA	94143	SAN FRANCISCO	USA	Cardiovascular Diseases Research	000	24	7/27/2015	NON-COMPETING CONTINUATION	$551,182
														Subtotal = $551,182

Issue Date FY: 2014 ( Subtotal = $542,499 )
2014	2014	UNIVERSITY OF CALIFORNIA-SAN FRANCISCO	BOX 0812	SAN FRANCISCO	CA	94143	SAN FRANCISCO	USA	Cardiovascular Diseases Research	000	23	7/21/2014	NON-COMPETING CONTINUATION	$542,499
														Subtotal = $542,499

Issue Date FY: 2013 ( Subtotal = $531,742 )
2013	2013	UNIVERSITY OF CALIFORNIA-SAN FRANCISCO	BOX 0812	SAN FRANCISCO	CA	94143	SAN FRANCISCO	USA	Cardiovascular Diseases Research	000	22	8/23/2013	NON-COMPETING CONTINUATION	$531,742
														Subtotal = $531,742

Issue Date FY: 2012 ( Subtotal = $412,450 )
2012	2012	UNIVERSITY OF CALIFORNIA-SAN FRANCISCO	BOX 0812	SAN FRANCISCO	CA	94143	SAN FRANCISCO	USA	Cardiovascular Diseases Research	000	21	3/23/2012	COMPETING CONTINUATION	$412,450
														Subtotal = $412,450

Issue Date FY: 2011 ( Subtotal = $242,250 )
2011	2011	UNIVERSITY OF CALIFORNIA-SAN FRANCISCO	BOX 0812	SAN FRANCISCO	CA	94143	SAN FRANCISCO	USA	Cardiovascular Diseases Research	000	20	8/5/2011	NON-COMPETING CONTINUATION	$242,250
														Subtotal = $242,250

Issue Date FY: 2010 ( Subtotal = $495,737 )
2010	2010	UNIVERSITY OF CALIFORNIA-SAN FRANCISCO	BOX 0812	SAN FRANCISCO	CA	94143	SAN FRANCISCO	USA	Cardiovascular Diseases Research	000	19	8/18/2010	NON-COMPETING CONTINUATION	$495,737
														Subtotal = $495,737

Issue Date FY: 2009 ( Subtotal = $491,590 )
2009	2009	UNIVERSITY OF CALIFORNIA-SAN FRANCISCO	BOX 0812	SAN FRANCISCO	CA	94143	SAN FRANCISCO	USA	Cardiovascular Diseases Research	000	18	7/27/2009	NON-COMPETING CONTINUATION	$491,590
														Subtotal = $491,590

Issue Date FY: 2008 ( Subtotal = $487,495 )
2008	2008	UNIVERSITY OF CALIFORNIA-SAN FRANCISCO	BOX 0812	SAN FRANCISCO	CA	94143	SAN FRANCISCO	USA	Cardiovascular Diseases Research	000	17	7/23/2008	NON-COMPETING CONTINUATION	$487,495
														Subtotal = $487,495

Issue Date FY: 2007 ( Subtotal = $487,495 )
2007	2007	UNIVERSITY OF CALIFORNIA-SAN FRANCISCO	BOX 0812	SAN FRANCISCO	CA	94143	SAN FRANCISCO	USA	Cardiovascular Diseases Research	000	16	6/7/2007	COMPETING CONTINUATION	$487,495
														Subtotal = $487,495

Issue Date FY: 2006 ( Subtotal = $266,932 )
2006	2006	UNIVERSITY OF CALIFORNIA-SAN FRANCISCO	BOX 0812	SAN FRANCISCO	CA	94143	SAN FRANCISCO	USA	Cardiovascular Diseases Research	000	15	7/14/2006	NON-COMPETING CONTINUATION	$266,932
														Subtotal = $266,932

Issue Date FY: 2004 ( Subtotal = $529,912 ) (Continued on the next page)
Grand Total All Awards = $12,143,096

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Molecular and Cellular Basis of Cardiovascular Disease

Award Number: T32HL007731

ORGANIZATION: NATIONAL HEART, LUNG, & BLOOD INSTITUTE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP

PERIOD OF PERFORMANCE START DATE: 07/01/1992

PERIOD OF PERFORMANCE END DATE: 05/31/2029

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