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UCSC Graduate Program in Genome Sciences

Award Number: T32HG012344
ORGANIZATION: NATIONAL HUMAN GENOME RESEARCH INSTITUTE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP
PERIOD OF PERFORMANCE START DATE: 07/01/2022
PERIOD OF PERFORMANCE END DATE: 06/30/2027

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UCSC Graduate Program in Genome Sciences - ABSTRACT The UCSC Graduate Training Program in Genome Science combines cutting-edge computational biology training in a multidisciplinary biomedical science and engineering environment. Among other strengths, UC Santa Cruz is a world leader in computational biology, bioinformatics, genomic technologies and RNA biology. The goals of the program are to prepare trainees for advanced academic and industry careers in biomedical genomics. Our training program develops critical thinking skills, provides rigorous hands-on training in computer science, statistics, and biological sciences, and develops scientific communication skills. The proposed program will provide support for six trainees, each with a two-year appointment. Our trainee applicant pool consists of PhD students who have already joined UCSC’s interdisciplinary genomics and biomedical sciences community and completed three hands-on laboratory rotations during their first year of study, at least one of which must be conducted in the laboratory of a GS Program faculty member. Genome Science trainees participate in several innovative training activities. Each year, our trainees will organize and run a bootcamp for each year’s incoming PhD cohort of students who are accepted by the Dept. of Biomolecular Engineering. This 10-day activity is designed and implemented by the T32 trainees with feedback and guidance from faculty. The centerpiece of the bootcamp is an ambitious hands-on activity for the incoming grad cohort to tackle. Previous activities have included building a functional DropSeq single-cell RNA sequencing machine (2017), as well as genome sequencing and assembly of the banana slug – UCSC’s mascot (2019). Trainees receive training in labs of 26 faculty, including a winner of the MacArthur Award, members of the National Academy of Sciences, and a Nobel Laureate. Formal coursework for trainees includes graduate- level instruction in bioethics, programming, practical genomics, statistics, and scientific writing. These courses cover essential topics in rigor and reproducibility and responsible conduct of research. Working with the Graduate Advising Committee and their faculty mentors, trainees develop Individual Development Plans which may involve further coursework to address specific deficiencies or special interests. In coordination with the NHGRI DAP program, trainees will also serve as mentors to undergraduate students. Program success will be assessed via several quantitative metrics of trainee productivity, such as the timing and number of publications and success in applying for extramural research funds, as well as career outcomes that are tracked following the award of PhDs. These metrics will be assessed by the Genome Sciences Executive Committee. The program is interdisciplinary, including 26 program faculty from 8 departments. Most trainees and approximately half of program faculty are affiliated with the Biomolecular Engineering Department, as nearly all BME faculty have genomics-focused research programs.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = $267,526 )
2026	2026	UNIVERSITY OF CALIFORNIA SANTA CRUZ	1156 HIGH ST	SANTA CRUZ	CA	95064	SANTA CRUZ	USA	Human Genome Research	000	5	7/30/2026	NON-COMPETING CONTINUATION	$267,526
														Subtotal = $267,526

Issue Date FY: 2025 ( Subtotal = $264,415 )
2025	2025	UNIVERSITY OF CALIFORNIA SANTA CRUZ	1156 HIGH ST	SANTA CRUZ	CA	95064	SANTA CRUZ	USA	Human Genome Research	000	4	7/25/2025	NON-COMPETING CONTINUATION	$264,415
														Subtotal = $264,415

Issue Date FY: 2024 ( Subtotal = $327,396 )
2024	2024	UNIVERSITY OF CALIFORNIA SANTA CRUZ	1156 HIGH ST	SANTA CRUZ	CA	95064	SANTA CRUZ	USA	Human Genome Research	000	3	7/29/2024	NON-COMPETING CONTINUATION	$327,396
														Subtotal = $327,396

Issue Date FY: 2023 ( Subtotal = $316,101 )
2023	2023	UNIVERSITY OF CALIFORNIA SANTA CRUZ	1156 HIGH ST	SANTA CRUZ	CA	95064	SANTA CRUZ	USA	Human Genome Research	000	2	6/21/2023	NON-COMPETING CONTINUATION	$316,101
														Subtotal = $316,101

Issue Date FY: 2022 ( Subtotal = $309,997 )
2022	2022	UNIVERSITY OF CALIFORNIA SANTA CRUZ	1156 HIGH ST	SANTA CRUZ	CA	95064	SANTA CRUZ	USA	Human Genome Research	000	1	7/1/2022	NEW	$309,997
														Subtotal = $309,997

Grand Total All Awards = $1,485,435

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UCSC Graduate Program in Genome Sciences

Award Number: T32HG012344

ORGANIZATION: NATIONAL HUMAN GENOME RESEARCH INSTITUTE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP

PERIOD OF PERFORMANCE START DATE: 07/01/2022

PERIOD OF PERFORMANCE END DATE: 06/30/2027

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