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Quantitative and Computational Biology Graduate Program

Award Number: T32HG003284
ORGANIZATION: NATIONAL HUMAN GENOME RESEARCH INSTITUTE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP
PERIOD OF PERFORMANCE START DATE: 08/18/2004
PERIOD OF PERFORMANCE END DATE: 07/31/2030

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Quantitative and Computational Biology Graduate Program - Abstract: The proposed activities will continue the highly successful work of the multidisciplinary NHGRI PhD training program administered by Princeton’s Lewis-Sigler Institute (LSI) for Integrative Genomics. The program was established twenty years ago by David Botstein, a pioneer of genomics research and education. The main objectives are to train students in how to collect and analyze increasingly complex genomics data, broadly defined, and provide a thorough education in how to integrate genomics with mechanistic studies of living systems. We have updated the program and refined it in order to keep up with the technical and conceptual advances of modern genomics research. We have expanded the ability of trainees to work with a range of mentors from several graduate programs at Princeton University, including the Program in Quantitative and Computational Biology (QCB) and its partner departments. Now, trainees can do their lab rotations and thesis research with any of 24 affiliated faculty working on subjects as diverse as the design of novel genomic technologies, statistics of genomic datasets, data integration, and genomics of human diseases. Students have more seminar opportunities, are assigned peer and faculty mentors, and have greater opportunities to craft an interdisciplinary PhD topic. The trainees also have new opportunities within the recently established research and educational initiatives at Princeton, including the Omenn-Darling Bioengineering Institute and Princeton Precision Health, both of which are headed by two faculty mentors in our training program. We request support for 10 pre-doctoral positions (i.e., maintaining our current level) per year. Each trainee is typically supported for a total of two years, with the remainder of funding coming from PIs’ grants and/or home departments. In addition to having access to the independently funded experimental and computing facilities of the LSI and partner departments at Princeton, trainees have opportunities to teach in an innovative undergraduate Integrated Science Curriculum, which continues to serve as a successful blueprint for quantitative education in the Life Sciences.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $406,850 )
2025	2025	THE TRUSTEES OF PRINCETON UNIVERSITY	1 NASSAU HALL	PRINCETON	NJ	08544	MERCER	USA	Human Genome Research	000	21	8/15/2025	COMPETING CONTINUATION	$406,850
														Subtotal = $406,850

Issue Date FY: 2024 ( Subtotal = $350,228 )
2024	2024	THE TRUSTEES OF PRINCETON UNIVERSITY	1 NASSAU HALL	PRINCETON	NJ	08544	MERCER	USA	Human Genome Research	000	20	8/6/2024	NON-COMPETING CONTINUATION	$350,228
														Subtotal = $350,228

Issue Date FY: 2023 ( Subtotal = $402,935 )
2023	2023	THE TRUSTEES OF PRINCETON UNIVERSITY	1 NASSAU HALL	PRINCETON	NJ	08544	MERCER	USA	Human Genome Research	000	19	5/1/2023	NON-COMPETING CONTINUATION	$402,935
														Subtotal = $402,935

Issue Date FY: 2022 ( Subtotal = $428,032 )
2022	2022	TRUSTEES OF PRINCETON UNIVERSITY, THE	1 NASSAU HALL	PRINCETON	NJ	08544	MERCER	USA	Human Genome Research	000	18	5/11/2022	NON-COMPETING CONTINUATION	$428,042
2022	2022	TRUSTEES OF PRINCETON UNIVERSITY, THE	1 NASSAU HALL	PRINCETON	NJ	08544	MERCER	USA	Human Genome Research	001	18	6/28/2022	NON-COMPETING CONTINUATION	-$10
														Subtotal = $428,032

Issue Date FY: 2021 ( Subtotal = $498,074 )
2021	2021	TRUSTEES OF PRINCETON UNIVERSITY, THE	1 NASSAU HALL	PRINCETON	NJ	08544	MERCER	USA	Human Genome Research	004	17	4/16/2021	NON-COMPETING CONTINUATION	$498,074
2021	2020	TRUSTEES OF PRINCETON UNIVERSITY, THE	1 NASSAU HALL	PRINCETON	NJ	08544	MERCER	USA	Human Genome Research	001	16	11/12/2020	COMPETING CONTINUATION	$21,956
2021	2020	TRUSTEES OF PRINCETON UNIVERSITY, THE	1 NASSAU HALL	PRINCETON	NJ	08544	MERCER	USA	Human Genome Research	003	16	2/5/2021	COMPETING CONTINUATION	$83,514
2021	2019	TRUSTEES OF PRINCETON UNIVERSITY, THE	1 NASSAU HALL	PRINCETON	NJ	08544	MERCER	USA	Human Genome Research	002	15	2/5/2021	NON-COMPETING CONTINUATION	-$83,514
2021	2019	TRUSTEES OF PRINCETON UNIVERSITY, THE	1 NASSAU HALL	PRINCETON	NJ	08544	MERCER	USA	Human Genome Research	000	15	11/12/2020	NON-COMPETING CONTINUATION	-$21,956
														Subtotal = $498,074

Issue Date FY: 2020 ( Subtotal = $514,456 )
2020	2020	TRUSTEES OF PRINCETON UNIVERSITY, THE	1 NASSAU HALL	PRINCETON	NJ	08544	MERCER	USA	Human Genome Research	001	16	5/8/2020	COMPETING CONTINUATION	$514,456
2020	2019	TRUSTEES OF PRINCETON UNIVERSITY, THE	1 NASSAU HALL	PRINCETON	NJ	08544	MERCER	USA	Human Genome Research	000	15	5/7/2020	NON-COMPETING CONTINUATION	$0
														Subtotal = $514,456

Issue Date FY: 2019 ( Subtotal = $472,188 )
2019	2019	TRUSTEES OF PRINCETON UNIVERSITY, THE	1 NASSAU HALL	PRINCETON	NJ	08544	MERCER	USA	Human Genome Research	000	15	4/16/2019	NON-COMPETING CONTINUATION	$472,188
														Subtotal = $472,188

Issue Date FY: 2018 ( Subtotal = $478,859 )
2018	2018	TRUSTEES OF PRINCETON UNIVERSITY, THE	1 NASSAU HALL	PRINCETON	NJ	08544	MERCER	USA	Human Genome Research	001	14	6/12/2018	NON-COMPETING CONTINUATION	$5,184
2018	2018	TRUSTEES OF PRINCETON UNIVERSITY, THE	1 NASSAU HALL	PRINCETON	NJ	08544	MERCER	USA	Human Genome Research	000	14	4/27/2018	NON-COMPETING CONTINUATION	$473,675
														Subtotal = $478,859

Issue Date FY: 2017 ( Subtotal = $473,675 )
2017	2017	TRUSTEES OF PRINCETON UNIVERSITY, THE	1 NASSAU HALL	PRINCETON	NJ	08544	MERCER	USA	Human Genome Research	001	13	7/19/2017	NON-COMPETING CONTINUATION	$5,054
2017	2017	TRUSTEES OF PRINCETON UNIVERSITY, THE	1 NASSAU HALL	PRINCETON	NJ	08544	MERCER	USA	Human Genome Research	000	13	5/5/2017	NON-COMPETING CONTINUATION	$468,621
														Subtotal = $473,675

Issue Date FY: 2016 ( Subtotal = $468,621 )
2016	2016	PRINCETON UNIVERSITY	POST OFFICE BOX 5292	PRINCETON	NJ	08544	MERCER	USA	Human Genome Research	000	12	4/22/2016	NON-COMPETING CONTINUATION	$468,621
														Subtotal = $468,621

Issue Date FY: 2015 ( Subtotal = $463,696 )
2015	2015	PRINCETON UNIVERSITY	POST OFFICE BOX 5292	PRINCETON	NJ	08544	MERCER	USA	Human Genome Research	000	11	4/30/2015	COMPETING CONTINUATION	$463,696
														Subtotal = $463,696

Issue Date FY: 2014 ( Subtotal = $531,889 )
2014	2014	PRINCETON UNIVERSITY	POST OFFICE BOX 5292	PRINCETON	NJ	08544	MERCER	USA	Human Genome Research	000	10	5/8/2014	SUPPLEMENT FOR EXPANSION	$531,889
														Subtotal = $531,889

Issue Date FY: 2013 ( Subtotal = $542,335 )
2013	2013	PRINCETON UNIVERSITY	POST OFFICE BOX 5292	PRINCETON	NJ	08544	MERCER	USA	Human Genome Research	000	10	7/22/2013	NON-COMPETING CONTINUATION	$542,335
														Subtotal = $542,335

Issue Date FY: 2012 ( Subtotal = $542,335 )
2012	2012	PRINCETON UNIVERSITY	POST OFFICE BOX 5292	PRINCETON	NJ	08544	MERCER	USA	Human Genome Research	000	9	7/16/2012	NON-COMPETING CONTINUATION	$542,335
														Subtotal = $542,335

Issue Date FY: 2011 ( Subtotal = $492,008 )
2011	2011	PRINCETON UNIVERSITY	POST OFFICE BOX 5292	PRINCETON	NJ	08544	MERCER	USA	Human Genome Research	000	8	7/20/2011	NON-COMPETING CONTINUATION	$492,008
														Subtotal = $492,008

Issue Date FY: 2010 ( Subtotal = $442,744 )
2010	2010	PRINCETON UNIVERSITY	POST OFFICE BOX 5292	PRINCETON	NJ	08544	MERCER	USA	Human Genome Research	000	7	9/24/2010	NON-COMPETING CONTINUATION	$442,744
														Subtotal = $442,744

Issue Date FY: 2009 ( Subtotal = $394,504 )
2009	2009	PRINCETON UNIVERSITY	POST OFFICE BOX 5292	PRINCETON	NJ	08544	MERCER	USA	Human Genome Research	001	6	7/23/2009	COMPETING CONTINUATION	$394,504
2009	2008	PRINCETON UNIVERSITY	POST OFFICE BOX 5292	PRINCETON	NJ	08544	MERCER	USA	Human Genome Research	000	5	7/23/2009	NON-COMPETING CONTINUATION	$0
														Subtotal = $394,504

Issue Date FY: 2008 ( Subtotal = $403,918 )
2008	2008	PRINCETON UNIVERSITY	POST OFFICE BOX 5292	PRINCETON	NJ	08544	MERCER	USA	Human Genome Research	000	5	8/22/2008	NON-COMPETING CONTINUATION	$403,918
														Subtotal = $403,918

Issue Date FY: 2007 ( Subtotal = $403,918 )
2007	2007	PRINCETON UNIVERSITY	POST OFFICE BOX 5292	PRINCETON	NJ	08544	MERCER	USA	Human Genome Research	000	4	8/13/2007	NON-COMPETING CONTINUATION	$403,918
														Subtotal = $403,918

Issue Date FY: 2006 ( Subtotal = $403,918 )
2006	2006	PRINCETON UNIVERSITY	POST OFFICE BOX 5292	PRINCETON	NJ	08544	MERCER	USA	Human Genome Research	000	3	8/3/2006	NON-COMPETING CONTINUATION	$403,918
														Subtotal = $403,918

Issue Date FY: 2004 ( Subtotal = $134,639 ) (Continued on the next page)
Grand Total All Awards = $9,249,822

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Quantitative and Computational Biology Graduate Program

Award Number: T32HG003284

ORGANIZATION: NATIONAL HUMAN GENOME RESEARCH INSTITUTE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP

PERIOD OF PERFORMANCE START DATE: 08/18/2004

PERIOD OF PERFORMANCE END DATE: 07/31/2030

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