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Training Program in the Molecular Bases of Eye Disease

Award Number: T32EY007145
ORGANIZATION: NATIONAL EYE INSTITUTE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP
PERIOD OF PERFORMANCE START DATE: 02/01/1997
PERIOD OF PERFORMANCE END DATE: 06/30/2028

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Training Program in the Molecular Bases of Eye Disease - Project Summary The Training Program in the Molecular Bases of Eye Diseases (MBED) is postdoctoral training program in the Department of Ophthalmology at Harvard Medical School (HMS) that aims to attract and mentor talented and motivated basic scientist trainees in vision research. The program is comprised of 33 faculty members who conduct research in a range of areas using a broad array of methods and models. The mentors represent a diversity of relevant disciplines including ocular immunology, vascular biology, neurobiology, regenerative medicine, gene therapy, bioinformatics, ocular surface, and drug delivery, to name a few. Moreover, the research faculty are focused on a number of important ocular pathologies such as age-related macular degeneration, glaucoma, retinal degenerations, corneal inflammation, wound healing, dry eye and corneal transplantation. This diversity provides a wide selection of training opportunities. Since it was first established in 1997, the MBED program has trained 93 trainees, four of whom have been under-represented minorities. Most of our trainees have continued some aspect of vision research. Their productivity is illustrated by their publications records. Each year the Training Grant supports three trainees for one year; each trainee spends at least two years total in training. A majority of the MBED faculty has extensive research experience, strong publication records, and successful records of mentoring. Each faculty member has an appointment in the department of Ophthalmology at HMS and is affiliated with Schepens Eye Research Institute of Mass Eye and Ear, Mass Eye and Ear, Harvard Medical School, Children’s Hospital or the Joslin Diabetes Research Center. All mentors are funded and most are supported by the National Eye Institute (NEI). The goal of the MBED Program is to provide trainees with expertise in cellular, biochemical and molecular approaches as well as knowledge and proficiency with relevant disease models. Importantly, the training provided by the MBED Program instills the ability to recognize and the address the important clinical and basic research questions challenging ophthalmology. The faculty are highly committed mentors as evidenced by the quality and success of their trainees. The location of the affiliated institutions in Boston provides an outstanding research environment with access to outstanding facilities and resources. Training includes dedicated mentoring, full-time research, didactic courses, ample opportunity for collaboration and networking, workshops on soft skills, as well as instruction in grant and manuscript writing and review, communications skills, the responsible conduct of research, and methods for enhancing reproducibility. Thus, MBED training encompasses all elements required to produce independent and successful vision researchers who have deep knowledge and understanding of the basic and clinical principles that are key to identifying and solving important ophthalmic problems.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $241,593 )
2025	2025	SCHEPENS EYE RESEARCH INSTITUTE, INC., THE	20 STANIFORD ST	BOSTON	MA	02114	SUFFOLK	USA	Vision Research	000	26	9/16/2025	NON-COMPETING CONTINUATION	$241,593
														Subtotal = $241,593

Issue Date FY: 2024 ( Subtotal = $186,846 )
2024	2024	SCHEPENS EYE RESEARCH INSTITUTE, INC., THE	20 STANIFORD ST	BOSTON	MA	02114	SUFFOLK	USA	Vision Research	002	25	7/15/2024	NON-COMPETING CONTINUATION	$186,846
2024	2023	SCHEPENS EYE RESEARCH INSTITUTE, INC., THE	20 STANIFORD ST	BOSTON	MA	02114	SUFFOLK	USA	Vision Research	001	24	7/11/2024	COMPETING CONTINUATION	$64,598
2024	2021	SCHEPENS EYE RESEARCH INSTITUTE, INC., THE	20 STANIFORD ST	BOSTON	MA	02114	SUFFOLK	USA	Vision Research	000	23	7/11/2024	NON-COMPETING CONTINUATION	-$64,598
														Subtotal = $186,846

Issue Date FY: 2023 ( Subtotal = $233,749 )
2023	2023	SCHEPENS EYE RESEARCH INSTITUTE, INC., THE	20 STANIFORD ST	BOSTON	MA	02114	SUFFOLK	USA	Vision Research	000	24	6/14/2023	COMPETING CONTINUATION	$233,749
														Subtotal = $233,749

Issue Date FY: 2021 ( Subtotal = $215,816 )
2021	2021	SCHEPENS EYE RESEARCH INSTITUTE, INC., THE	20 STANIFORD ST	BOSTON	MA	02114	SUFFOLK	USA	Vision Research	000	23	9/9/2021	NON-COMPETING CONTINUATION	$215,816
														Subtotal = $215,816

Issue Date FY: 2020 ( Subtotal = $97,710 )
2020	2020	SCHEPENS EYE RESEARCH INSTITUTE, INC., THE	20 STANIFORD ST	BOSTON	MA	02114	SUFFOLK	USA	Vision Research	000	22	6/8/2020	NON-COMPETING CONTINUATION	$97,710
														Subtotal = $97,710

Issue Date FY: 2019 ( Subtotal = $198,625 )
2019	2019	SCHEPENS EYE RESEARCH INSTITUTE, INC., THE	20 STANIFORD ST	BOSTON	MA	02114	SUFFOLK	USA	Vision Research	000	21	6/4/2019	NON-COMPETING CONTINUATION	$198,625
														Subtotal = $198,625

Issue Date FY: 2018 ( Subtotal = $67,754 )
2018	2018	SCHEPENS EYE RESEARCH INSTITUTE, INC., THE	20 STANIFORD ST	BOSTON	MA	02114	SUFFOLK	USA	Vision Research	008	20	6/18/2018	NON-COMPETING CONTINUATION	$67,754
2018	2017	SCHEPENS EYE RESEARCH INSTITUTE, INC., THE	20 STANIFORD ST	BOSTON	MA	02114	SUFFOLK	USA	Vision Research	003	19	2/27/2018	COMPETING CONTINUATION	$374,113
2018	2017	SCHEPENS EYE RESEARCH INSTITUTE, INC., THE	20 STANIFORD ST	BOSTON	MA	02114	SUFFOLK	USA	Vision Research	004	19	6/6/2018	COMPETING CONTINUATION	-$160,793
2018	2015	SCHEPENS EYE RESEARCH INSTITUTE, INC., THE	20 STANIFORD ST	BOSTON	MA	02114	SUFFOLK	USA	Vision Research	002	18	2/27/2018	NON-COMPETING CONTINUATION	-$220,542
2018	2015	SCHEPENS EYE RESEARCH INSTITUTE, INC., THE	20 STANIFORD ST	BOSTON	MA	02114	SUFFOLK	USA	Vision Research	005	18	6/6/2018	NON-COMPETING CONTINUATION	$7,222
2018	2014	SCHEPENS EYE RESEARCH INSTITUTE, INC., THE	20 STANIFORD ST	BOSTON	MA	02114	SUFFOLK	USA	Vision Research	006	17	6/6/2018	NON-COMPETING CONTINUATION	$151,392
2018	2014	SCHEPENS EYE RESEARCH INSTITUTE, INC., THE	20 STANIFORD ST	BOSTON	MA	02114	SUFFOLK	USA	Vision Research	001	17	2/27/2018	NON-COMPETING CONTINUATION	-$151,392
2018	2013	SCHEPENS EYE RESEARCH INSTITUTE, INC., THE	20 STANIFORD ST	BOSTON	MA	02114	SUFFOLK	USA	Vision Research	000	16	2/27/2018	NON-COMPETING CONTINUATION	-$2,179
2018	2013	SCHEPENS EYE RESEARCH INSTITUTE, INC., THE	20 STANIFORD ST	BOSTON	MA	02114	SUFFOLK	USA	Vision Research	007	16	6/6/2018	NON-COMPETING CONTINUATION	$2,179
														Subtotal = $67,754

Issue Date FY: 2017 ( Subtotal = $132,243 )
2017	2017	SCHEPENS EYE RESEARCH INSTITUTE, INC., THE	20 STANIFORD ST	BOSTON	MA	02114	SUFFOLK	USA	Vision Research	001	19	9/13/2017	COMPETING CONTINUATION	$132,243
2017	2015	SCHEPENS EYE RESEARCH INSTITUTE, INC., THE	20 STANIFORD ST	BOSTON	MA	02114	SUFFOLK	USA	Vision Research	000	18	12/5/2016	NON-COMPETING CONTINUATION	$0
														Subtotal = $132,243

Issue Date FY: 2015 ( Subtotal = $220,542 )
2015	2015	SCHEPENS EYE RESEARCH INSTITUTE	20 STANIFORD STREET	BOSTON	MA	02114	SUFFOLK	USA	Vision Research	000	18	6/8/2015	NON-COMPETING CONTINUATION	$220,542
														Subtotal = $220,542

Issue Date FY: 2014 ( Subtotal = $151,392 )
2014	2014	SCHEPENS EYE RESEARCH INSTITUTE	20 STANIFORD STREET	BOSTON	MA	02114	SUFFOLK	USA	Vision Research	000	17	6/23/2014	NON-COMPETING CONTINUATION	$151,392
														Subtotal = $151,392

Issue Date FY: 2013 ( Subtotal = $206,625 )
2013	2013	SCHEPENS EYE RESEARCH INSTITUTE	20 STANIFORD STREET	BOSTON	MA	02114	SUFFOLK	USA	Vision Research	000	16	7/19/2013	NON-COMPETING CONTINUATION	$206,625
														Subtotal = $206,625

Issue Date FY: 2012 ( Subtotal = $214,937 )
2012	2012	SCHEPENS EYE RESEARCH INSTITUTE	20 STANIFORD STREET	BOSTON	MA	02114	SUFFOLK	USA	Vision Research	000	15	6/20/2012	NON-COMPETING CONTINUATION	$214,937
														Subtotal = $214,937

Issue Date FY: 2011 ( Subtotal = $157,176 )
2011	2011	SCHEPENS EYE RESEARCH INSTITUTE	20 STANIFORD STREET	BOSTON	MA	02114	SUFFOLK	USA	Vision Research	000	14	6/14/2011	COMPETING CONTINUATION	$157,176
														Subtotal = $157,176

Issue Date FY: 2010 ( Subtotal = $237,670 )
2010	2010	SCHEPENS EYE RESEARCH INSTITUTE	20 STANIFORD STREET	BOSTON	MA	02114	SUFFOLK	USA	Vision Research	000	13	3/19/2010	NON-COMPETING CONTINUATION	$237,670
														Subtotal = $237,670

Issue Date FY: 2009 ( Subtotal = $144,262 )
2009	2009	SCHEPENS EYE RESEARCH INSTITUTE	20 STANIFORD STREET	BOSTON	MA	02114	SUFFOLK	USA	Vision Research	001	12	6/12/2009	NON-COMPETING CONTINUATION	$2,073
2009	2009	SCHEPENS EYE RESEARCH INSTITUTE	20 STANIFORD STREET	BOSTON	MA	02114	SUFFOLK	USA	Vision Research	000	12	2/9/2009	NON-COMPETING CONTINUATION	$142,189
														Subtotal = $144,262

Issue Date FY: 2008 ( Subtotal = $180,427 )
2008	2008	SCHEPENS EYE RESEARCH INSTITUTE	20 STANIFORD STREET	BOSTON	MA	02114	SUFFOLK	USA	Vision Research	000	11	4/4/2008	NON-COMPETING CONTINUATION	$180,427
														Subtotal = $180,427

Issue Date FY: 2007 ( Subtotal = $44,195 )
2007	2007	SCHEPENS EYE RESEARCH INSTITUTE	20 STANIFORD STREET	BOSTON	MA	02114	SUFFOLK	USA	Vision Research	000	10	3/16/2007	NON-COMPETING CONTINUATION	$44,195
														Subtotal = $44,195

Issue Date FY: 2006 ( Subtotal = $0 )
2006	2006	SCHEPENS EYE RESEARCH INSTITUTE	20 STANIFORD STREET	BOSTON	MA	02114	SUFFOLK	USA	Vision Research	000	9	2/20/2006	COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2004 ( Subtotal = $258,849 )
2004	2004	SCHEPENS EYE RESEARCH INSTITUTE	20 STANIFORD STREET	BOSTON	MA	02114	SUFFOLK	USA	Vision Research	000	7	5/10/2004	NON-COMPETING CONTINUATION	$258,849
														Subtotal = $258,849

Grand Total All Awards = $4,328,360

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Training Program in the Molecular Bases of Eye Disease

Award Number: T32EY007145

ORGANIZATION: NATIONAL EYE INSTITUTE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP

PERIOD OF PERFORMANCE START DATE: 02/01/1997

PERIOD OF PERFORMANCE END DATE: 06/30/2028

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