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Training in Cardiovascular Imaging Research

Award Number: T32EB003841
ORGANIZATION: NATIONAL INSTITUTE Of BIOMEDICAL IMAGING & BIOENGINEERING
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP

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Program Director/Principal Investigator (Last, First, Middle): Kramer, Christopher M. Cardiovascular disease is the major cause of morbidity and mortality in the United States. In fact, 43% of all deaths are due to coronary heart disease and heart failure is on the rise, expecting to increase in prevalence by 46% between 2012 and 2030. The need for improved noninvasive methods to detect early disease and to help manage patients with chronic disease has therefore never been as critical. Technical advances in noninvasive cardiovascular imaging have resulted in increasing use over recent years. Nuclear cardiology and echocardiography are mature technologies that are commonly used in clinical practice. Cardiovascular magnetic resonance imaging (CMR), computed tomographic angiography (CTA), and positron emission tomography (PET) are playing a growing role in the clinical assessment of CVD and are relatively new to cardiovascular training programs. The number of physicians who have in-depth expertise in the physics, engineering, and molecular applications in all 5 major cardiovascular imaging modalities remains limited. The University of Virginia (UVA) is one of a handful of centers in the U.S. that have high-level clinical, physics, engineering, and molecular expertise in all cardiovascular imaging modalities, as well as a track record of training physicians in research. Over the past decade, trainees have been highly productive in terms of publication and half have gone on to academic careers in outstanding institutions around the U.S. Two former trainees joined the UVA faculty and have been NIH-funded, with 2 K23 and 1 R01 awards between them. The purpose of this grant renewal proposal is to continue and further develop the training program that provides comprehensive training in cardiovascular imaging research. The program provides trainees with outstanding opportunities to interact closely with imaging physicists and engineers who together offer the promise of improvements in both the clinical applications of these newer technologies and further development of and applications of translational imaging. Trainees have dual mentorship from a PhD imaging scientist and a MD clinician investigator. The goal of the training is to develop the next generation of academic investigators in cardiovascular imaging who can interact across disciplines. Trainees undergo a rigorous 2-year research training program following a 2-year clinical cardiovascular training program completed at the UVA or a 3-year program completed at another institution. Up to 3 fellows are enrolled at any one time. A complete didactic program is offered including instruction in imaging physics and engineering, biostatistics, epidemiology, clinical research methodology, and medical ethics. Fellows receive training in clinical CMR, CTA, and PET. Research training is comprehensive and combines clinical and basic cardiovascular imaging research for each trainee with any of the modalities. PHS 398/2590 (Rev. 06/09) Page Continuation Format Page


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2023 ( Subtotal = $278,079 )
2023	2023	RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA	1001 N EMMET ST	CHARLOTTESVILLE	VA	22903	CHARLOTTESVILLE CITY	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	000	18	6/30/2023	NON-COMPETING CONTINUATION	$278,079
														Subtotal = $278,079

Issue Date FY: 2022 ( Subtotal = $85,843 )
2022	2022	RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA	1001 N EMMET ST	CHARLOTTESVILLE	VA	22903	CHARLOTTESVILLE CITY	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	010	17	9/15/2022	NON-COMPETING CONTINUATION	$72,588
2022	2022	RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA	1001 N EMMET ST	CHARLOTTESVILLE	VA	22903	CHARLOTTESVILLE CITY	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	003	17	8/5/2022	NON-COMPETING CONTINUATION	$13,255
2022	2021	RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA	1001 N EMMET ST	CHARLOTTESVILLE	VA	22903	CHARLOTTESVILLE CITY	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	002	16	12/27/2021	COMPETING CONTINUATION	$333,155
2022	2021	RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA	1001 N EMMET ST	CHARLOTTESVILLE	VA	22903	CHARLOTTESVILLE CITY	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	006	16	8/29/2022	COMPETING CONTINUATION	-$333,155
2022	2021	RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA	1001 N EMMET ST	CHARLOTTESVILLE	VA	22903	CHARLOTTESVILLE CITY	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	009	16	8/31/2022	COMPETING CONTINUATION	$333,155
2022	2020	RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA	1001 N EMMET ST	CHARLOTTESVILLE	VA	22903	CHARLOTTESVILLE CITY	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	005	15	8/29/2022	NON-COMPETING CONTINUATION	$248,871
2022	2020	RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA	1001 N EMMET ST	CHARLOTTESVILLE	VA	22903	CHARLOTTESVILLE CITY	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	001	15	12/27/2021	NON-COMPETING CONTINUATION	-$248,871
2022	2020	RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA	1001 N EMMET ST	CHARLOTTESVILLE	VA	22903	CHARLOTTESVILLE CITY	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	008	15	8/31/2022	NON-COMPETING CONTINUATION	-$248,871
2022	2019	RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA	1001 N EMMET ST	CHARLOTTESVILLE	VA	22903	CHARLOTTESVILLE CITY	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	004	14	8/29/2022	NON-COMPETING CONTINUATION	$84,284
2022	2019	RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA	1001 N EMMET ST	CHARLOTTESVILLE	VA	22903	CHARLOTTESVILLE CITY	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	000	14	12/27/2021	NON-COMPETING CONTINUATION	-$84,284
2022	2019	RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA	1001 N EMMET ST	CHARLOTTESVILLE	VA	22903	CHARLOTTESVILLE CITY	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	007	14	8/31/2022	NON-COMPETING CONTINUATION	-$84,284
														Subtotal = $85,843

Issue Date FY: 2021 ( Subtotal = $260,464 )
2021	2021	RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA	1001 N EMMET ST	CHARLOTTESVILLE	VA	22903	CHARLOTTESVILLE CITY	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	000	16	9/20/2021	COMPETING CONTINUATION	$260,464
														Subtotal = $260,464

Issue Date FY: 2020 ( Subtotal = $248,871 )
2020	2020	RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA	1001 N EMMET ST	CHARLOTTESVILLE	VA	22903	CHARLOTTESVILLE CITY	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	000	15	7/20/2020	NON-COMPETING CONTINUATION	$248,871
														Subtotal = $248,871

Issue Date FY: 2019 ( Subtotal = $239,202 )
2019	2019	RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA	1001 N EMMET ST	CHARLOTTESVILLE	VA	22903	CHARLOTTESVILLE CITY	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	001	14	8/22/2019	NON-COMPETING CONTINUATION	$239,202
2019	2018	RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA	1001 N EMMET ST	CHARLOTTESVILLE	VA	22903	CHARLOTTESVILLE CITY	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	000	13	8/22/2019	NON-COMPETING CONTINUATION	$0
														Subtotal = $239,202

Issue Date FY: 2018 ( Subtotal = $83,237 )
2018	2018	RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA	1001 N EMMET ST	CHARLOTTESVILLE	VA	22903	CHARLOTTESVILLE CITY	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	000	13	7/2/2018	NON-COMPETING CONTINUATION	$83,237
2018	2017	RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA	1001 N EMMET ST	CHARLOTTESVILLE	VA	22903	CHARLOTTESVILLE CITY	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	001	12	7/17/2018	NON-COMPETING CONTINUATION	$0
														Subtotal = $83,237

Issue Date FY: 2017 ( Subtotal = $91,030 )
2017	2017	RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA	1001 N EMMET ST	CHARLOTTESVILLE	VA	22903	CHARLOTTESVILLE CITY	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	003	12	8/7/2017	NON-COMPETING CONTINUATION	$91,030
2017	2016	RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA	1001 N EMMET ST	CHARLOTTESVILLE	VA	22903	CHARLOTTESVILLE CITY	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	002	11	12/29/2016	COMPETING CONTINUATION	$402,428
2017	2015	RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA	1001 N EMMET ST	CHARLOTTESVILLE	VA	22903	CHARLOTTESVILLE CITY	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	001	10	12/29/2016	NON-COMPETING CONTINUATION	-$252,904
2017	2014	RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA	1001 N EMMET ST	CHARLOTTESVILLE	VA	22903	CHARLOTTESVILLE CITY	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	000	9	12/29/2016	NON-COMPETING CONTINUATION	-$149,524
														Subtotal = $91,030

Issue Date FY: 2016 ( Subtotal = $145,347 )
2016	2016	UNIVERSITY OF VIRGINIA	P.O. BOX 400195	CHARLOTTESVILLE	VA	22904	CHARLOTTESVILLE CITY	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	001	11	5/24/2016	COMPETING CONTINUATION	$145,347
2016	2015	UNIVERSITY OF VIRGINIA	PO BOX 400195	CHARLOTTESVILLE	VA	229044195	CHARLOTTESVILLE CITY	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	000	10	5/19/2016	NON-COMPETING CONTINUATION	$0
														Subtotal = $145,347

Issue Date FY: 2015 ( Subtotal = $252,904 )
2015	2015	UNIVERSITY OF VIRGINIA	P.O. BOX 400195	CHARLOTTESVILLE	VA	22904	CHARLOTTESVILLE CITY	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	000	10	6/22/2015	NON-COMPETING CONTINUATION	$252,904
														Subtotal = $252,904

Issue Date FY: 2014 ( Subtotal = $168,960 )
2014	2014	UNIVERSITY OF VIRGINIA	P.O. BOX 400195	CHARLOTTESVILLE	VA	22904	CHARLOTTESVILLE CITY	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	000	9	6/13/2014	NON-COMPETING CONTINUATION	$168,960
														Subtotal = $168,960

Issue Date FY: 2013 ( Subtotal = $248,049 )
2013	2013	UNIVERSITY OF VIRGINIA	P.O. BOX 400195	CHARLOTTESVILLE	VA	22904	CHARLOTTESVILLE CITY	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	000	8	4/16/2013	NON-COMPETING CONTINUATION	$248,049
														Subtotal = $248,049

Issue Date FY: 2012 ( Subtotal = $257,876 )
2012	2012	UNIVERSITY OF VIRGINIA	P.O. BOX 400195	CHARLOTTESVILLE	VA	22904	CHARLOTTESVILLE CITY	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	000	7	5/9/2012	NON-COMPETING CONTINUATION	$257,876
														Subtotal = $257,876

Issue Date FY: 2011 ( Subtotal = $147,920 )
2011	2011	UNIVERSITY OF VIRGINIA	P.O. BOX 400195	CHARLOTTESVILLE	VA	22904	CHARLOTTESVILLE CITY	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	002	6	5/13/2011	COMPETING CONTINUATION	$4,316
2011	2011	UNIVERSITY OF VIRGINIA	P.O. BOX 400195	CHARLOTTESVILLE	VA	22904	CHARLOTTESVILLE CITY	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	001	6	4/1/2011	COMPETING CONTINUATION	$273,506
2011	2008	UNIVERSITY OF VIRGINIA	P.O. BOX 400195	CHARLOTTESVILLE	VA	22904	CHARLOTTESVILLE CITY	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	000	5	3/29/2011	NON-COMPETING CONTINUATION	-$129,902
														Subtotal = $147,920

Issue Date FY: 2010 ( Subtotal = $129,902 )
2010	2008	UNIVERSITY OF VIRGINIA	PO BOX 400195	CHARLOTTESVILLE	VA	22904	CHARLOTTESVILLE CITY	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	000	5	5/25/2010	NON-COMPETING CONTINUATION	$0
2010	2008	UNIVERSITY OF VIRGINIA	P.O. BOX 400195	CHARLOTTESVILLE	VA	22904	CHARLOTTESVILLE CITY	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	001	5	7/26/2010	NON-COMPETING CONTINUATION	$129,902
														Subtotal = $129,902

Issue Date FY: 2008 ( Subtotal = $247,345 )
2008	2008	UNIVERSITY OF VIRGINIA	PO BOX 400195	CHARLOTTESVILLE	VA	22904	CHARLOTTESVILLE CITY	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	000	5	4/4/2008	NON-COMPETING CONTINUATION	$247,345
														Subtotal = $247,345

Issue Date FY: 2007 ( Subtotal = $232,046 ) (Continued on the next page)
Grand Total All Awards = $3,478,347

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Training in Cardiovascular Imaging Research

Award Number: T32EB003841

ORGANIZATION: NATIONAL INSTITUTE Of BIOMEDICAL IMAGING & BIOENGINEERING

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP

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