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Translational Explorations in Substance Use Disorders

Award Number: T32DA007287
ORGANIZATION: NATIONAL INSTITUTE ON DRUG ABUSE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP
PERIOD OF PERFORMANCE START DATE: 09/01/1994
PERIOD OF PERFORMANCE END DATE: 06/30/2028

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Translational Explorations in Substance Use Disorders - Drug overdose deaths and substance use disorders (SUDs) constitute a major, high-impact health problem in the U.S. This renewal of the training grant Translational Explorations in Substance Use Disorders (T32 DA007287) at the University of Texas Medical Branch (UTMB) proposes to address the large gap between the problem and efficacious solutions by mentoring the next generation of innovative scientists committed to the search for answers. Under the auspices of the UTMB Center for Addiction Research (CAR), the history of our Training Program demonstrates a wealth of career development successes, extensive collaborative networks, and expertise in cross-disciplinary SUD research conducted with contemporary technologies.. During the current funding period, 95% of our mentees were retained in research positions with ~74% in SUD-related careers. Together, pre- and postdoctoral mentees generated a total of 140+ publications in the past 10 years (36 during the current funding period with numerous manuscripts in progress). Our predoctoral mentees are producing, on average, six published manuscripts each (two as first-author). Of our postdoctoral mentees from the current funding period, three have become faculty, two are in residency programs, one is in industry. Moving forward, our goal is to provide mentees with key transferrable skills accessible through innovative SUD mechanistic studies, drug discovery projects, prevention, and public health initiatives. We will harness Health Analytics to accomplish this goal by incorporating research strategies across barriers towards biobehavioral signatures of SUDs. Our objectives are to (1) integrate mentees into SUD research; (2) instill mastery of SUD sciences and key skills through outstanding role models; (3) impart critical thinking skills to tackle strategic questions in our field; (4) provide first-rate preparation for independent careers in SUD sciences; (5) inculcate best practices in scientific ethics and rigor across the full spectrum of possibilities; (6) broaden the dissemination of our learnings though peer-reviewed publications and community venues to improve public health, productivity, and life fulfillment. Strategies to achieve these objectives include providing well-funded, state-of-the-art research opportunities, facilities, effective mentoring plans (Mentor Mosaics), challenging curricula, supportive interactive programs (e.g., SciPopUp, short-term research rotations), plus first-rate activities that develop the professional skills needed for advancement towards an independent career (e.g., Grant and Publication Action Group, Innovation and Entrepreneurship). The outcome of our efforts is successful, trainees as complete scientists equipped with the tools to advance the mechanistic knowledge of SUDs as well as deliver new approaches to alleviate the challenges with drug misuse and SUDs


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = $194,103 )
2026	2026	UNIVERSITY OF TEXAS MEDICAL BRANCH AT GALVESTON	301 UNIVERSITY BLVD	GALVESTON	TX	77555	GALVESTON	USA	Drug Use and Addiction Research Programs	000	29	5/13/2026	NON-COMPETING CONTINUATION	$194,103
														Subtotal = $194,103

Issue Date FY: 2025 ( Subtotal = $279,033 )
2025	2025	UNIVERSITY OF TEXAS MEDICAL BRANCH AT GALVESTON	301 UNIVERSITY BLVD	GALVESTON	TX	77555	GALVESTON	USA	Drug Use and Addiction Research Programs	001	28	6/19/2025	NON-COMPETING CONTINUATION	$279,033
2025	2024	UNIVERSITY OF TEXAS MEDICAL BRANCH AT GALVESTON	301 UNIVERSITY BLVD	GALVESTON	TX	77555	GALVESTON	USA	Drug Use and Addiction Research Programs	000	27	4/2/2025	NON-COMPETING CONTINUATION	$0
														Subtotal = $279,033

Issue Date FY: 2024 ( Subtotal = $275,042 )
2024	2024	UNIVERSITY OF TEXAS MEDICAL BRANCH AT GALVESTON	301 UNIVERSITY BLVD	GALVESTON	TX	77555	GALVESTON	USA	Drug Use and Addiction Research Programs	003	27	6/5/2024	NON-COMPETING CONTINUATION	$275,042
2024	2023	UNIVERSITY OF TEXAS MEDICAL BRANCH AT GALVESTON	301 UNIVERSITY BLVD	GALVESTON	TX	77555	GALVESTON	USA	Drug Use and Addiction Research Programs	001	26	1/19/2024	COMPETING CONTINUATION	$111,106
2024	2022	UNIVERSITY OF TEXAS MEDICAL BRANCH AT GALVESTON	301 UNIVERSITY BLVD	GALVESTON	TX	77555	GALVESTON	USA	Drug Use and Addiction Research Programs	002	25	1/19/2024	SUPPLEMENT FOR EXPANSION	-$73,565
2024	2021	UNIVERSITY OF TEXAS MEDICAL BRANCH AT GALVESTON	301 UNIVERSITY BLVD	GALVESTON	TX	77555	GALVESTON	USA	Drug Use and Addiction Research Programs	000	25	1/19/2024	NON-COMPETING CONTINUATION	-$37,541
														Subtotal = $275,042

Issue Date FY: 2023 ( Subtotal = $259,555 )
2023	2023	UNIVERSITY OF TEXAS MEDICAL BRANCH AT GALVESTON	301 UNIVERSITY BLVD	GALVESTON	TX	77555	GALVESTON	USA	Drug Use and Addiction Research Programs	000	26	4/6/2023	COMPETING CONTINUATION	$259,555
														Subtotal = $259,555

Issue Date FY: 2022 ( Subtotal = $73,565 )
2022	2022	UNIVERSITY OF TEXAS MEDICAL BRANCH AT GALVESTON	301 UNIVERSITY BLVD	GALVESTON	TX	77555	GALVESTON	USA	Drug Use and Addiction Research Programs	000	25	5/4/2022	SUPPLEMENT FOR EXPANSION	$73,565
2022	2021	UNIVERSITY OF TEXAS MEDICAL BRANCH AT GALVESTON	301 UNIVERSITY BLVD	GALVESTON	TX	77555	GALVESTON	USA	Drug Use and Addiction Research Programs	001	25	7/12/2022	NON-COMPETING CONTINUATION	$0
														Subtotal = $73,565

Issue Date FY: 2021 ( Subtotal = $229,199 )
2021	2021	UNIVERSITY OF TEXAS MEDICAL BRANCH AT GALVESTON	301 UNIVERSITY BLVD	GALVESTON	TX	77555	GALVESTON	USA	Drug Use and Addiction Research Programs	000	25	4/29/2021	NON-COMPETING CONTINUATION	$229,199
														Subtotal = $229,199

Issue Date FY: 2020 ( Subtotal = $94,041 )
2020	2020	UNIVERSITY OF TEXAS MEDICAL BRANCH AT GALVESTON	301 UNIVERSITY BLVD	GALVESTON	TX	77555	GALVESTON	USA	Drug Use and Addiction Research Programs	001	24	4/29/2020	NON-COMPETING CONTINUATION	$94,041
2020	2019	UNIVERSITY OF TEXAS MEDICAL BRANCH AT GALVESTON	301 UNIVERSITY BLVD	GALVESTON	TX	77555	GALVESTON	USA	Drug Use and Addiction Research Programs	000	23	1/30/2020	NON-COMPETING CONTINUATION	$0
														Subtotal = $94,041

Issue Date FY: 2019 ( Subtotal = $310,433 )
2019	2019	UNIVERSITY OF TEXAS MEDICAL BRANCH AT GALVESTON	301 UNIVERSITY BLVD	GALVESTON	TX	77555	GALVESTON	USA	Drug Use and Addiction Research Programs	001	23	6/21/2019	NON-COMPETING CONTINUATION	$310,433
2019	2018	UNIVERSITY OF TEXAS MEDICAL BRANCH AT GALVESTON	301 UNIVERSITY BLVD	GALVESTON	TX	77555	GALVESTON	USA	Drug Use and Addiction Research Programs	000	22	3/14/2019	NON-COMPETING CONTINUATION	$0
														Subtotal = $310,433

Issue Date FY: 2018 ( Subtotal = $300,104 )
2018	2018	UNIVERSITY OF TEXAS MEDICAL BRANCH AT GALVESTON	301 UNIVERSITY BLVD	GALVESTON	TX	77555	GALVESTON	USA	Drug Use and Addiction Research Programs	007	22	5/21/2018	NON-COMPETING CONTINUATION	$300,104
2018	2017	UNIVERSITY OF TEXAS MEDICAL BRANCH AT GALVESTON	301 UNIVERSITY BLVD	GALVESTON	TX	77555	GALVESTON	USA	Drug Use and Addiction Research Programs	001	21	11/27/2017	COMPETING CONTINUATION	$226,481
2018	2017	UNIVERSITY OF TEXAS MEDICAL BRANCH AT GALVESTON	301 UNIVERSITY BLVD	GALVESTON	TX	77555	GALVESTON	USA	Drug Use and Addiction Research Programs	002	20	11/27/2017	SUPPLEMENT FOR EXPANSION	-$1
2018	2017	UNIVERSITY OF TEXAS MEDICAL BRANCH AT GALVESTON	301 UNIVERSITY BLVD	GALVESTON	TX	77555	GALVESTON	USA	Drug Use and Addiction Research Programs	004	21	1/31/2018	COMPETING CONTINUATION	$155,576
2018	2017	UNIVERSITY OF TEXAS MEDICAL BRANCH AT GALVESTON	301 UNIVERSITY BLVD	GALVESTON	TX	77555	GALVESTON	USA	Drug Use and Addiction Research Programs	006	21	3/16/2018	COMPETING CONTINUATION	-$155,576
2018	2016	UNIVERSITY OF TEXAS MEDICAL BRANCH AT GALVESTON	301 UNIVERSITY BLVD	GALVESTON	TX	77555	GALVESTON	USA	Drug Use and Addiction Research Programs	005	20	3/16/2018	EXTENSION WITH OR WITHOUT FUNDS	$155,576
2018	2016	UNIVERSITY OF TEXAS MEDICAL BRANCH AT GALVESTON	301 UNIVERSITY BLVD	GALVESTON	TX	77555	GALVESTON	USA	Drug Use and Addiction Research Programs	003	20	1/31/2018	EXTENSION WITH OR WITHOUT FUNDS	-$155,576
2018	2016	UNIVERSITY OF TEXAS MEDICAL BRANCH AT GALVESTON	301 UNIVERSITY BLVD	GALVESTON	TX	77555	GALVESTON	USA	Drug Use and Addiction Research Programs	000	20	11/27/2017	EXTENSION WITH OR WITHOUT FUNDS	-$226,480
														Subtotal = $300,104

Issue Date FY: 2017 ( Subtotal = $292,588 )
2017	2017	UNIVERSITY OF TEXAS MEDICAL BRANCH AT GALVESTON	301 UNIVERSITY BLVD	GALVESTON	TX	77555	GALVESTON	USA	Drug Use and Addiction Research Programs	007	21	6/26/2017	COMPETING CONTINUATION	$1,516
2017	2017	UNIVERSITY OF TEXAS MEDICAL BRANCH AT GALVESTON	301 UNIVERSITY BLVD	GALVESTON	TX	77555	GALVESTON	USA	Drug Use and Addiction Research Programs	005	20	3/23/2017	SUPPLEMENT FOR EXPANSION	$1
2017	2017	UNIVERSITY OF TEXAS MEDICAL BRANCH AT GALVESTON	301 UNIVERSITY BLVD	GALVESTON	TX	77555	GALVESTON	USA	Drug Use and Addiction Research Programs	006	21	4/5/2017	COMPETING CONTINUATION	$291,071
2017	2016	UNIVERSITY OF TEXAS MEDICAL BRANCH AT GALVESTON	301 UNIVERSITY BLVD	GALVESTON	TX	77555	GALVESTON	USA	Drug Use and Addiction Research Programs	004	20	1/3/2017	EXTENSION WITH OR WITHOUT FUNDS	$200,282
2017	2015	UNIVERSITY OF TEXAS MEDICAL BRANCH AT GALVESTON	301 UNIVERSITY BLVD	GALVESTON	TX	77555	GALVESTON	USA	Drug Use and Addiction Research Programs	003	19	1/3/2017	NON-COMPETING CONTINUATION	-$162,138
2017	2014	UNIVERSITY OF TEXAS MEDICAL BRANCH AT GALVESTON	301 UNIVERSITY BLVD	GALVESTON	TX	77555	GALVESTON	USA	Drug Use and Addiction Research Programs	001	18	1/3/2017	NON-COMPETING CONTINUATION	-$1
2017	2014	UNIVERSITY OF TEXAS MEDICAL BRANCH AT GALVESTON	301 UNIVERSITY BLVD	GALVESTON	TX	77555	GALVESTON	USA	Drug Use and Addiction Research Programs	002	18	1/3/2017	SUPPLEMENT FOR EXPANSION	-$33,471
2017	2013	UNIVERSITY OF TEXAS MEDICAL BRANCH AT GALVESTON	301 UNIVERSITY BLVD	GALVESTON	TX	77555	GALVESTON	USA	Drug Use and Addiction Research Programs	000	17	1/3/2017	NON-COMPETING CONTINUATION	-$4,672
														Subtotal = $292,588

Issue Date FY: 2016 ( Subtotal = $316,895 )
2016	2016	UNIVERSITY OF TEXAS, MEDICAL BRANCH AT GALVESTON	1000 STRAND	GALVESTON	TX	77550	GALVESTON	USA	Drug Use and Addiction Research Programs	000	20	6/15/2016	EXTENSION WITH OR WITHOUT FUNDS	$316,895
														Subtotal = $316,895

Issue Date FY: 2015 ( Subtotal = $162,138 )
2015	2015	UNIVERSITY OF TEXAS, MEDICAL BRANCH AT GALVESTON	1000 STRAND	GALVESTON	TX	77550	GALVESTON	USA	Drug Use and Addiction Research Programs	000	19	6/10/2015	NON-COMPETING CONTINUATION	$162,138
														Subtotal = $162,138

Issue Date FY: 2014 ( Subtotal = $33,472 )
2014	2014	UNIVERSITY OF TEXAS, MEDICAL BRANCH AT GALVESTON	1000 STRAND	GALVESTON	TX	77550	GALVESTON	USA	Drug Use and Addiction Research Programs	001	18	6/30/2014	SUPPLEMENT FOR EXPANSION	$33,471
2014	2014	UNIVERSITY OF TEXAS, MEDICAL BRANCH AT GALVESTON	1000 STRAND	GALVESTON	TX	77550	GALVESTON	USA	Drug Use and Addiction Research Programs	000	18	6/27/2014	NON-COMPETING CONTINUATION	$1
														Subtotal = $33,472

Issue Date FY: 2013 ( Subtotal = $263,736 )
2013	2013	UNIVERSITY OF TEXAS, MEDICAL BRANCH AT GALVESTON	1000 STRAND	GALVESTON	TX	77550	GALVESTON	USA	Drug Use and Addiction Research Programs	000	17	6/24/2013	NON-COMPETING CONTINUATION	$263,736
														Subtotal = $263,736

Grand Total All Awards = $4,915,947

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Translational Explorations in Substance Use Disorders

Award Number: T32DA007287

ORGANIZATION: NATIONAL INSTITUTE ON DRUG ABUSE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP

PERIOD OF PERFORMANCE START DATE: 09/01/1994

PERIOD OF PERFORMANCE END DATE: 06/30/2028

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