PROJECT SUMMARY/ABSTRACT
The Oncology-focused Postdoctoral Training In Care Delivery and Symptom Science (OPTICS) T32 program
will mentor and train physicians and scientists with PhDs in social or quantitative sciences to conduct research
focused on innovative cancer care delivery that narrows the gap between outcomes that are possible based on
contemporary scientific understanding of cancer prevention and treatment and outcomes that are actually
achieved. This persistent gap results in a critical need for translational researchers who are focused on risk
reduction, symptom science, and innovative care delivery and have rigorous training in research methods
required for care delivery transformation and leadership of health system–level interventions to reduce
pervasive inequities in treatment outcomes. The cornerstone of the OPTICS program will be a 2-year mentored
research experience in which trainees will conduct research aligned with one or more of four thematic areas: 1)
Data Science, 2) Risk Mitigation, 3) Symptom Science, and 4) Care Delivery. An emphasis on remediation of
inequities generated by structural racism and classism is a core program tenet. OPTICS trainees will receive 1)
intensive mentorship and the resources necessary to execute a focused research project in one or more of the
thematic areas; 2) training in core methods necessary for impactful research through coursework, seminars,
workshops, and reading groups; and 3) training in skills required for career building, including protocol
development and execution, management, grant writing, team building, patient engagement, dry-laboratory
organization, and the responsible conduct of research. OPTICS will be co-led by 2 PhDs and 2 MDs at
Memorial Sloan Kettering Cancer Center (MSK) with long track records of impactful research, mentorship, and
successful knowledge translation. This structure will attract diverse candidates and afford participants methods
training and the ability to launch interventions in the community and the clinic. OPTICS will train 6 postdoctoral
fellows each year (3 new appointees and 3 re-appointees) with a team of 36 core program faculty, 10 emerging
mentors, and 6 research supporters with relevant supporting skills, expertise, and resources. Required core
program training at the New York City campus of MSK and its partner Weill Cornell Medical College is
supplemented by an array of elective learning opportunities customized to each trainee's needs and learning
style. Trainees will obtain the skills necessary to develop, test, and implement new approaches to optimizing
patients' experiences by focusing on risk reduction, symptom control, communication, and new models of
cancer care delivery. These skills are crucial to address the challenges brought about by the tremendous
growth in the complexity and chronicity of cancer care. OPTICS aims to prepare trainees for impactful careers
focused on innovations to optimize cancer care quality, equity, and translation of knowledge to ensure that
discoveries made in the laboratory and clinic realize their full impact on population health and well-being.