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Biochemical and Chemical Training for Cancer Research

Award Number: T32CA009582
ORGANIZATION: NATIONAL CANCER INSTITUTE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP
PERIOD OF PERFORMANCE START DATE: 06/01/1987
PERIOD OF PERFORMANCE END DATE: 05/31/2028

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Biochemical and Chemical Training for Cancer Research - Project Abstract This renewal application seeks support for the training of predoctoral students and postdoctoral fellows in biochemical, chemical, biological and structural approaches for cancer research. The training program integrates contemporary cancer biology (e.g., oncogenes and tumor suppressors, signal transduction, oncogenic transcription factors, DNA modifications, cell cycle control, genomic surveillance) with the allied fields of chemical biology, chemical-genetics, and structural biology. Over the past 35 years, this Training Program has an outstanding training record and seeks to continue this multidisciplinary training program that is composed of 29 preceptors from nine academic departments and programs representing the Vanderbilt University School of Medicine, School of Engineering, the College of Arts and Sciences and the Vanderbilt University Medical Center. The training program is conducted within a vibrant academic environment and is supported by close interactions with the Vanderbilt-Ingram NCI-designated Comprehensive Cancer Center, the Vanderbilt Institute of Chemical Biology, and the Vanderbilt Center for Structural Biology, all of which offer resources for trainees and preceptors. In addition to departmental and preceptor-specific laboratory instruction, each trainee receives cancer- related training in the form of three courses focused on cancer biology and experimental cancer research. An Interdisciplinary Graduate Program (IGP), the Chemical and Physical Biology Program (CPB), and an independent graduate program in Chemistry all academically support predoctoral trainees. This renewal applications continues several recent enhancements to our training program including a Precision Cancer Medicine course that provides an immersive clinical experience. In the COVID era, we have also lauched 15 bioinformics micro-training courses for large datasets. We have an active mentoring program that includes former student trainees, postdoctoral mentors, and faculty mentors, which ensures the continued development of academic skills for cancer research and career development. Significant institutional investment in training programs, core facilities, state-of-the-art laboratories and equipment that provide technology resources applicable to cancer biology and molecular structures also enhance trainee development. The institution has also made additional investiments to provide an inclusing training environment that his free of any form of harassment or discrimination while emphasizing rigor, reproducibility and transparency. This integrated training in biochemistry, chemistry, structural biology, and cancer biology is critical to the molecular understanding of cancer and the development of new approaches to molecularly targeted therapeutics.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $422,231 )
2025	2025	VANDERBILT UNIVERSITY	110 21ST AVE S	NASHVILLE	TN	37203	DAVIDSON	USA	Cancer Research Manpower	001	38	5/29/2025	NON-COMPETING CONTINUATION	-$35,662
2025	2025	VANDERBILT UNIVERSITY	110 21ST AVE S	NASHVILLE	TN	37203	DAVIDSON	USA	Cancer Research Manpower	002	38	7/2/2025	NON-COMPETING CONTINUATION	$0
2025	2025	VANDERBILT UNIVERSITY	110 21ST AVE S	NASHVILLE	TN	37203	DAVIDSON	USA	Cancer Research Manpower	000	38	5/7/2025	NON-COMPETING CONTINUATION	$457,893
														Subtotal = $422,231

Issue Date FY: 2024 ( Subtotal = $374,943 )
2024	2024	VANDERBILT UNIVERSITY	110 21ST AVE S	NASHVILLE	TN	37203	DAVIDSON	USA	Cancer Research Manpower	002	37	6/10/2024	NON-COMPETING CONTINUATION	$374,943
2024	2023	VANDERBILT UNIVERSITY	110 21ST AVE S	NASHVILLE	TN	37203	DAVIDSON	USA	Cancer Research Manpower	001	36	6/4/2024	COMPETING CONTINUATION	$202,570
2024	2022	VANDERBILT UNIVERSITY	110 21ST AVE S	NASHVILLE	TN	37203	DAVIDSON	USA	Cancer Research Manpower	000	35	6/4/2024	NON-COMPETING CONTINUATION	-$202,570
														Subtotal = $374,943

Issue Date FY: 2023 ( Subtotal = $370,188 )
2023	2023	VANDERBILT UNIVERSITY	110 21ST AVE S	NASHVILLE	TN	37203	DAVIDSON	USA	Cancer Research Manpower	001	36	5/24/2023	COMPETING CONTINUATION	$370,188
2023	2022	VANDERBILT UNIVERSITY	110 21ST AVE S	NASHVILLE	TN	37203	DAVIDSON	USA	Cancer Research Manpower	000	35	5/18/2023	NON-COMPETING CONTINUATION	$0
														Subtotal = $370,188

Issue Date FY: 2022 ( Subtotal = $302,048 )
2022	2022	VANDERBILT UNIVERSITY, THE	110 21ST AVENUE S STE 800	NASHVILLE	TN	37203	DAVIDSON	USA	Cancer Research Manpower	000	35	5/26/2022	NON-COMPETING CONTINUATION	$302,048
														Subtotal = $302,048

Issue Date FY: 2021 ( Subtotal = $328,873 )
2021	2021	VANDERBILT UNIVERSITY, THE	110 21ST AVENUE S STE 800	NASHVILLE	TN	37203	DAVIDSON	USA	Cancer Research Manpower	000	34	4/29/2021	NON-COMPETING CONTINUATION	$328,873
														Subtotal = $328,873

Issue Date FY: 2020 ( Subtotal = $312,906 )
2020	2020	VANDERBILT UNIVERSITY, THE	110 21ST AVENUE S STE 800	NASHVILLE	TN	37203	DAVIDSON	USA	Cancer Research Manpower	000	33	4/28/2020	NON-COMPETING CONTINUATION	$312,906
														Subtotal = $312,906

Issue Date FY: 2019 ( Subtotal = $367,802 )
2019	2019	VANDERBILT UNIVERSITY, THE	110 21ST AVENUE S STE 800	NASHVILLE	TN	37203	DAVIDSON	USA	Cancer Research Manpower	000	32	4/19/2019	NON-COMPETING CONTINUATION	$367,802
														Subtotal = $367,802

Issue Date FY: 2018 ( Subtotal = $383,570 )
2018	2018	VANDERBILT UNIVERSITY, THE	110 21ST AVENUE S STE 800	NASHVILLE	TN	37203	DAVIDSON	USA	Cancer Research Manpower	001	31	6/6/2018	COMPETING CONTINUATION	$383,570
2018	2018	VANDERBILT UNIVERSITY, THE	110 21ST AVENUE S STE 800	NASHVILLE	TN	37203	DAVIDSON	USA	Cancer Research Manpower	003	31	9/27/2018	COMPETING CONTINUATION	$202,969
2018	2017	VANDERBILT UNIVERSITY, THE	2301 VANDERBILT PL	NASHVILLE	TN	37235	DAVIDSON	USA	Cancer Research Manpower	002	30	9/27/2018	NON-COMPETING CONTINUATION	-$202,969
2018	2017	VANDERBILT UNIVERSITY, THE	2301 VANDERBILT PL	NASHVILLE	TN	37235	DAVIDSON	USA	Cancer Research Manpower	000	30	5/31/2018	NON-COMPETING CONTINUATION	$0
														Subtotal = $383,570

Issue Date FY: 2017 ( Subtotal = $355,836 )
2017	2017	VANDERBILT UNIVERSITY, THE	211 KIRKLAND HALL	NASHVILLE	TN	37240	DAVIDSON	USA	Cancer Research Manpower	001	30	5/22/2017	NON-COMPETING CONTINUATION	$350,192
2017	2017	VANDERBILT UNIVERSITY, THE	211 KIRKLAND HALL	NASHVILLE	TN	37240	DAVIDSON	USA	Cancer Research Manpower	002	30	7/14/2017	NON-COMPETING CONTINUATION	$2,022
2017	2017	VANDERBILT UNIVERSITY, THE	211 KIRKLAND HALL	NASHVILLE	TN	37240	DAVIDSON	USA	Cancer Research Manpower	000	29	12/26/2016	SUPPLEMENT FOR EXPANSION	$3,622
														Subtotal = $355,836

Issue Date FY: 2016 ( Subtotal = $349,773 )
2016	2016	VANDERBILT UNIVERSITY HOSPITAL, CHILDREN'S REHAB UNIT	1161 21ST AVENUE SOUTH	NASHVILLE	TN	37232	DAVIDSON	USA	Cancer Research Manpower	000	29	6/10/2016	EXTENSION WITH OR WITHOUT FUNDS	$349,773
														Subtotal = $349,773

Issue Date FY: 2015 ( Subtotal = $355,797 )
2015	2015	VANDERBILT UNIVERSITY HOSPITAL, CHILDREN'S REHAB UNIT	1161 21ST AVENUE SOUTH	NASHVILLE	TN	37232	DAVIDSON	USA	Cancer Research Manpower	000	28	5/12/2015	NON-COMPETING CONTINUATION	$355,797
														Subtotal = $355,797

Issue Date FY: 2014 ( Subtotal = $322,072 )
2014	2014	VANDERBILT UNIVERSITY HOSPITAL, CHILDREN'S REHAB UNIT	1161 21ST AVENUE SOUTH	NASHVILLE	TN	37232	DAVIDSON	USA	Cancer Research Manpower	000	27	5/20/2014	NON-COMPETING CONTINUATION	$322,072
														Subtotal = $322,072

Issue Date FY: 2013 ( Subtotal = $340,026 )
2013	2013	VANDERBILT UNIVERSITY HOSPITAL, CHILDREN'S REHAB UNIT	1161 21ST AVENUE SOUTH	NASHVILLE	TN	37232	DAVIDSON	USA	Cancer Research Manpower	000	26	5/10/2013	COMPETING CONTINUATION	$340,026
														Subtotal = $340,026

Issue Date FY: 2012 ( Subtotal = $292,046 )
2012	2012	VANDERBILT UNIVERSITY HOSPITAL, CHILDREN'S REHAB UNIT	1161 21ST AVENUE SOUTH	NASHVILLE	TN	37232	DAVIDSON	USA	Cancer Research Manpower	000	25	5/31/2012	NON-COMPETING CONTINUATION	$292,046
														Subtotal = $292,046

Issue Date FY: 2011 ( Subtotal = $320,299 )
2011	2011	VANDERBILT UNIVERSITY HOSPITAL, CHILDREN'S REHAB UNIT	1161 21ST AVENUE SOUTH	NASHVILLE	TN	37232	DAVIDSON	USA	Cancer Research Manpower	000	24	5/24/2011	NON-COMPETING CONTINUATION	$320,299
														Subtotal = $320,299

Issue Date FY: 2010 ( Subtotal = $304,317 )
2010	2010	VANDERBILT UNIVERSITY HOSPITAL, CHILDREN'S REHAB UNIT	1161 21ST AVENUE SOUTH	NASHVILLE	TN	37232	DAVIDSON	USA	Cancer Research Manpower	000	23	5/21/2010	NON-COMPETING CONTINUATION	$304,317
														Subtotal = $304,317

Issue Date FY: 2009 ( Subtotal = $273,252 )
2009	2009	VANDERBILT UNIVERSITY HOSPITAL, CHILDREN'S REHAB UNIT	1161 21ST AVENUE SOUTH	NASHVILLE	TN	37232	DAVIDSON	USA	Cancer Research Manpower	000	22	6/2/2009	NON-COMPETING CONTINUATION	$273,252
														Subtotal = $273,252

Issue Date FY: 2008 ( Subtotal = $250,003 )
2008	2008	VANDERBILT UNIVERSITY HOSPITAL, CHILDREN'S REHAB UNIT	1161 21ST AVENUE SOUTH	NASHVILLE	TN	37232	DAVIDSON	USA	Cancer Research Manpower	000	21	5/15/2008	COMPETING CONTINUATION	$250,003
														Subtotal = $250,003

Issue Date FY: 2007 ( Subtotal = $309,094 )
2007	2007	VANDERBILT UNIVERSITY HOSPITAL, CHILDREN'S REHAB UNIT	1161 21ST AVENUE SOUTH	NASHVILLE	TN	37232	DAVIDSON	USA	Cancer Research Manpower	000	20	3/9/2007	NON-COMPETING CONTINUATION	$309,094
														Subtotal = $309,094

Issue Date FY: 2006 ( Subtotal = $334,875 )
2006	2006	VANDERBILT UNIVERSITY HOSPITAL, CHILDREN'S REHAB UNIT	1161 21ST AVENUE SOUTH	NASHVILLE	TN	37232	DAVIDSON	USA	Cancer Research Manpower	000	19	5/8/2006	NON-COMPETING CONTINUATION	$334,875
														Subtotal = $334,875

Grand Total All Awards = $8,683,424

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Biochemical and Chemical Training for Cancer Research

Award Number: T32CA009582

ORGANIZATION: NATIONAL CANCER INSTITUTE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP

PERIOD OF PERFORMANCE START DATE: 06/01/1987

PERIOD OF PERFORMANCE END DATE: 05/31/2028

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