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Predoctoral Training: Innovative Technologies for Natural Products and Integrative Medicine Research

Award Number: T32AT008938
ORGANIZATION: CENTER FOR DRUG EVALUATION AND RESEARCH, NIH
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP
PERIOD OF PERFORMANCE START DATE: 03/01/2016
PERIOD OF PERFORMANCE END DATE: 03/31/2026

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Predoctoral Training: Innovative Technologies for Natural Products and Integrative Medicine Research - Enter the text here that is the new abstract information for your application. This section must be no longer than 30 lines of text. Natural products (particularly botanical dietary supplements) are a billion-dollar industry in the US and continue to serve as an important source for the development of new therapeutics. Trained biomedical researchers are needed to evaluate the chemical composition, activity, and mechanism of action of medicinally used natural products. The National Center for Complementary and Integrative Health (NCCIH) recognizes this need in their 2016 Strategic Plan, with the stated goal to “support research training and career development opportunities to increase the number and quality of scientists trained to conduct rigorous, cutting-edge research on complementary and integrative health practices.” The University of North Carolina at Greensboro (UNCG) is a unique and ideal location for such training to occur. Our PhD program in Medicinal Biochemistry emphasizes natural products and integrative medicine research, and we have a strong collaborative network of faculty mentors with relevant research programs. UNCG participates in two major NCCIH funded centers that focus on rigorous scientific investigation of botanical natural products, the Center for High Throughput Functional Annotation of Natural Products and the Center of Excellence for Natural Product Drug Interaction Research. To leverage the exceptional training environment at UNCG, we propose to renew a productive T32 program that has just finished its first period of funding. The program is tailored to fit the needs of individual students, with different opportunities provided to those on academic and industrial career paths. A unique element of our program is training in the application of cutting-edge technologies for the analysis of complex botanical mixtures. Trainees receive hands-on instruction in this area, making use of our exceptional NMR and mass spectrometry facilities. Our objective is to prepare trainees to transition into independent, natural products related research careers. During its inaugural funding cycle, the program was highly successful towards this goal, with our three graduates securing research positions in the academic or private sector. Our trainees have also disseminated important research findings, with a total of 67 presentations at conferences and 23 publication coauthorships. With this renewal application, we build on these past successes and on our assessment outcomes to deliver a plan for student training that will ultimately advance research on the safe and effective use of natural products and integrative medicine.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $188,839 )
2025	2025	UNIVERSITY OF NORTH CAROLINA AT GREENSBORO	1000 SPRING GARDEN ST	GREENSBORO	NC	27412	GUILFORD	USA	Research and Training in Complementary and Integrative Health	000	10	4/16/2025	NON-COMPETING CONTINUATION	$188,839
														Subtotal = $188,839

Issue Date FY: 2024 ( Subtotal = $188,839 )
2024	2024	UNIVERSITY OF NORTH CAROLINA AT GREENSBORO	1000 SPRING GARDEN ST	GREENSBORO	NC	27412	GUILFORD	USA	Research and Training in Complementary and Integrative Health	001	9	6/26/2024	NON-COMPETING CONTINUATION	$7,530
2024	2024	UNIVERSITY OF NORTH CAROLINA AT GREENSBORO	1000 SPRING GARDEN ST	GREENSBORO	NC	27412	GUILFORD	USA	Research and Training in Complementary and Integrative Health	000	9	3/28/2024	NON-COMPETING CONTINUATION	$181,309
														Subtotal = $188,839

Issue Date FY: 2023 ( Subtotal = $101,309 )
2023	2023	UNIVERSITY OF NORTH CAROLINA AT GREENSBORO	1000 SPRING GARDEN STREET	GREENSBORO	NC	27412	GUILFORD	USA	Research and Training in Complementary and Integrative Health	000	8	4/18/2023	NON-COMPETING CONTINUATION	$101,309
														Subtotal = $101,309

Issue Date FY: 2022 ( Subtotal = $97,240 )
2022	2022	UNIVERSITY OF NORTH CAROLINA AT GREENSBORO	1000 SPRING GARDEN STREET	GREENSBORO	NC	27412	GUILFORD	USA	Research and Training in Complementary and Integrative Health	000	7	4/1/2022	NON-COMPETING CONTINUATION	$94,147
2022	2022	UNIVERSITY OF NORTH CAROLINA AT GREENSBORO	1000 SPRING GARDEN STREET	GREENSBORO	NC	27412	GUILFORD	USA	Research and Training in Complementary and Integrative Health	001	7	6/24/2022	NON-COMPETING CONTINUATION	$3,093
														Subtotal = $97,240

Issue Date FY: 2021 ( Subtotal = $164,147 )
2021	2021	UNIVERSITY OF NORTH CAROLINA AT GREENSBORO	1000 SPRING GARDEN STREET	GREENSBORO	NC	27412	GUILFORD	USA	Research and Training in Complementary and Integrative Health	001	6	3/31/2021	COMPETING CONTINUATION	$164,147
2021	2021	UNIVERSITY OF NORTH CAROLINA AT GREENSBORO	1000 SPRING GARDEN STREET	GREENSBORO	NC	27412	GUILFORD	USA	Research and Training in Complementary and Integrative Health	003	6	8/7/2021	COMPETING CONTINUATION	$119,445
2021	2020	UNIVERSITY OF NORTH CAROLINA AT GREENSBORO	1000 SPRING GARDEN STREET	GREENSBORO	NC	27412	GUILFORD	USA	Research and Training in Complementary and Integrative Health	002	5	8/7/2021	NON-COMPETING CONTINUATION	-$119,445
2021	2020	UNIVERSITY OF NORTH CAROLINA AT GREENSBORO	1000 SPRING GARDEN STREET	GREENSBORO	NC	27412	GUILFORD	USA	Research and Training in Complementary and Integrative Health	000	5	3/29/2021	NON-COMPETING CONTINUATION	$0
														Subtotal = $164,147

Issue Date FY: 2020 ( Subtotal = $155,016 )
2020	2020	UNIVERSITY OF NORTH CAROLINA AT GREENSBORO	1000 SPRING GARDEN STREET	GREENSBORO	NC	27412	GUILFORD	USA	Research and Training in Complementary and Integrative Health	000	5	2/20/2020	NON-COMPETING CONTINUATION	$155,016
														Subtotal = $155,016

Issue Date FY: 2019 ( Subtotal = $152,839 )
2019	2019	UNIVERSITY OF NORTH CAROLINA AT GREENSBORO	1000 SPRING GARDEN STREET	GREENSBORO	NC	27412	GUILFORD	USA	Research and Training in Complementary and Integrative Health	000	4	2/28/2019	NON-COMPETING CONTINUATION	$152,839
														Subtotal = $152,839

Issue Date FY: 2018 ( Subtotal = $150,714 )
2018	2018	UNIVERSITY OF NORTH CAROLINA AT GREENSBORO	1000 SPRING GARDEN STREET	GREENSBORO	NC	27412	GUILFORD	USA	Research and Training in Complementary and Integrative Health	001	3	5/14/2018	NON-COMPETING CONTINUATION	$2,074
2018	2018	UNIVERSITY OF NORTH CAROLINA AT GREENSBORO	1000 SPRING GARDEN STREET	GREENSBORO	NC	27412	GUILFORD	USA	Research and Training in Complementary and Integrative Health	000	3	2/7/2018	NON-COMPETING CONTINUATION	$148,640
														Subtotal = $150,714

Issue Date FY: 2017 ( Subtotal = $146,618 )
2017	2017	UNIVERSITY OF NORTH CAROLINA AT GREENSBORO	1000 SPRING GARDEN ST	GREENSBORO	NC	27412	GUILFORD	USA	Research and Training in Complementary and Integrative Health	000	2	3/1/2017	NON-COMPETING CONTINUATION	$146,618
														Subtotal = $146,618

Issue Date FY: 2016 ( Subtotal = $79,362 )
2016	2016	UNIVERSITY OF NORTH CAROLINA AT GREENSBORO	70 BOX, 26173	GREENSBORO	NC	27402	GUILFORD	USA	Research and Training in Complementary and Integrative Health	000	1	2/16/2016	NEW	$79,362
														Subtotal = $79,362

Grand Total All Awards = $1,424,923

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Predoctoral Training: Innovative Technologies for Natural Products and Integrative Medicine Research

Award Number: T32AT008938

ORGANIZATION: CENTER FOR DRUG EVALUATION AND RESEARCH, NIH

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP

PERIOD OF PERFORMANCE START DATE: 03/01/2016

PERIOD OF PERFORMANCE END DATE: 03/31/2026

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