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Training Program in Infectious Diseases in the Immunocompromised Host

Award Number: T32AI118690
ORGANIZATION: NATIONAL INSTITUTE OF ALLERGY & INFECTIOUS DISEASES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP
PERIOD OF PERFORMANCE START DATE: 08/01/2016
PERIOD OF PERFORMANCE END DATE: 07/31/2026

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Training Program in Infectious Diseases in the Immunocompromised Host - PROJECT SUMMARY Our interdisciplinary training program, based at the Fred Hutchinson Cancer Research Center (Fred Hutch), focuses on Infectious Diseases in the Immunocompromised Host. Our objective is to recruit and train outstanding physician-scientists and postdoctoral PhD scientists to perform basic, translational and clinical research, using state-of-the-art methods and analytical techniques. Our overarching goal is to train the next generation of leaders in the field, who will use their expertise to advance our understanding of infectious disease biology and pathogenesis, and to develop novel strategies to prevent, treat and control infectious diseases in high-risk immunocompromised patients. There is increasing demand for research training in this field: infection remains a major cause of morbidity and mortality for immunocompromised hosts, and millions are at risk or affected by established pathogens and emerging pathogens such as SARS-CoV-2. The population of immunocompromised individuals in the United States continues to grow, driven by advances in transplantation techniques and cancer treatments, increased survival of these patients, and the development of novel drugs and biological agents to treat autoimmune diseases. As part of an NCI-designated cancer consortium whose renowned faculty have contributed landmark advances in the field of infectious diseases of the immunocompromised host for the past 40 years, and whose expertise collectively encompass all facets of this field, Fred Hutch is uniquely positioned to successfully lead this training program. In partnership with the University of Washington (UW), the Infectious Disease Sciences Program of Fred Hutch has an excellent, multi-decade track record of training physician-scientists and postdoctoral PhD scientists who launch independent research careers in academia, government research, or industry leadership positions. Our funded T32 grant has allowed us to expand our training program and solidify funding for trainees in this specialized area of infectious diseases. We seek to maintain this high standard of training; the T32 will support 2 new, qualified trainees (MDs and/or PhDs) per year, for 3 years of training each. T32 trainees pursue one of three consolidated research tracks that represent the unique strengths of our immunocompromised host program and its mentors: 1) Clinical Research, Infection Prevention, and Stewardship; 2) Immunology/Immunogenetics; and 3) Microbiome and Pathogenesis. These tracks provide training in unique aspects of this field and will assure that trainees develop expertise in epidemiology, diagnosis, management and host-pathogen interactions. All trainees participate in a rigorous core curriculum consisting of courses, lectures, retreats, research and targeted career development activities; trainees also have the opportunity to complete a master’s degree at UW. Our training program helps to address the national need for researchers that focus their clinical and/or laboratory investigation on Infectious Diseases in the Immunocompromised Host, and provides those trainees with the skills and expertise to successfully transition into independent research careers.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2024 ( Subtotal = $436,073 )
2024	2024	FRED HUTCHINSON CANCER CENTER	1100 FAIRVIEW AVE N	SEATTLE	WA	98109	KING	USA	Allergy and Infectious Diseases Research	000	10	5/30/2024	NON-COMPETING CONTINUATION	$436,073
														Subtotal = $436,073

Issue Date FY: 2023 ( Subtotal = $396,407 )
2023	2023	FRED HUTCHINSON CANCER CENTER	1100 FAIRVIEW AVE N	SEATTLE	WA	98109	KING	USA	Allergy and Infectious Diseases Research	008	9	6/30/2023	NON-COMPETING CONTINUATION	$365,300
2023	2022	FRED HUTCHINSON CANCER CENTER	1100 FAIRVIEW AVE N	SEATTLE	WA	98109	KING	USA	Allergy and Infectious Diseases Research	003	8	11/21/2022	SUPPLEMENT FOR EXPANSION	$269,997
2023	2022	FRED HUTCHINSON CANCER CENTER	1100 FAIRVIEW AVE N	SEATTLE	WA	98109	KING	USA	Allergy and Infectious Diseases Research	000	8	11/4/2022	NON-COMPETING CONTINUATION	-$474,512
2023	2022	FRED HUTCHINSON CANCER CENTER	1100 FAIRVIEW AVE N	SEATTLE	WA	98109	KING	USA	Allergy and Infectious Diseases Research	005	8	3/22/2023	NON-COMPETING CONTINUATION	$0
2023	2022	FRED HUTCHINSON CANCER CENTER	1100 FAIRVIEW AVE N	SEATTLE	WA	98109	KING	USA	Allergy and Infectious Diseases Research	001	8	11/4/2022	SUPPLEMENT FOR EXPANSION	-$269,997
2023	2022	FRED HUTCHINSON CANCER CENTER	1100 FAIRVIEW AVE N	SEATTLE	WA	98109	KING	USA	Allergy and Infectious Diseases Research	002	8	11/17/2022	NON-COMPETING CONTINUATION	$474,512
2023	2022	FRED HUTCHINSON CANCER CENTER	1100 FAIRVIEW AVE N	SEATTLE	WA	98109	KING	USA	Allergy and Infectious Diseases Research	004	8	1/11/2023	NON-COMPETING CONTINUATION	$31,107
2023	2021	FRED HUTCHINSON CANCER CENTER	1100 FAIRVIEW AVE N	SEATTLE	WA	98109	KING	USA	Allergy and Infectious Diseases Research	007	7	5/23/2023	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$2,000
2023	2021	FRED HUTCHINSON CANCER RESEARCH CENTER	1100 FAIRVIEW AVE N J6-300	SEATTLE	WA	98109	KING	USA	Allergy and Infectious Diseases Research	006	6	5/23/2023	COMPETING CONTINUATION	-$2,000
														Subtotal = $396,407

Issue Date FY: 2022 ( Subtotal = $744,510 )
2022	2022	FRED HUTCHINSON CANCER CENTER	1100 FAIRVIEW AVE N	SEATTLE	WA	98109	KING	USA	Allergy and Infectious Diseases Research	011	8	9/13/2022	NON-COMPETING CONTINUATION	$474,512
2022	2022	FRED HUTCHINSON CANCER CENTER	1100 FAIRVIEW AVE N	SEATTLE	WA	98109	KING	USA	Allergy and Infectious Diseases Research	012	8	9/19/2022	SUPPLEMENT FOR EXPANSION	$269,997
2022	2021	FRED HUTCHINSON CANCER CENTER	1100 FAIRVIEW AVE N	SEATTLE	WA	98109	KING	USA	Allergy and Infectious Diseases Research	006	7	8/9/2022	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$1
2022	2021	FRED HUTCHINSON CANCER RESEARCH CENTER	1100 FAIRVIEW AVE N J6-300	SEATTLE	WA	98109	KING	USA	Allergy and Infectious Diseases Research	003	6	5/27/2022	COMPETING CONTINUATION	-$323,614
2022	2021	FRED HUTCHINSON CANCER RESEARCH CENTER	1100 FAIRVIEW AVE N J6-300	SEATTLE	WA	98109	KING	USA	Allergy and Infectious Diseases Research	007	6	8/9/2022	COMPETING CONTINUATION	-$224,821
2022	2021	FRED HUTCHINSON CANCER RESEARCH CENTER	1100 FAIRVIEW AVE N J6-300	SEATTLE	WA	98109	KING	USA	Allergy and Infectious Diseases Research	002	6	4/6/2022	COMPETING CONTINUATION	$324,898
2022	2021	FRED HUTCHINSON CANCER RESEARCH CENTER	1100 FAIRVIEW AVE N J6-300	SEATTLE	WA	98109	KING	USA	Allergy and Infectious Diseases Research	010	6	9/13/2022	COMPETING CONTINUATION	$0
2022	2021	FRED HUTCHINSON CANCER RESEARCH CENTER	1100 FAIRVIEW AVE N J6-300	SEATTLE	WA	98109	KING	USA	Allergy and Infectious Diseases Research	005	6	8/9/2022	COMPETING CONTINUATION	-$1
2022	2021	FRED HUTCHINSON CANCER CENTER	1100 FAIRVIEW AVE N	SEATTLE	WA	98109	KING	USA	Allergy and Infectious Diseases Research	004	7	5/27/2022	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$323,615
2022	2021	FRED HUTCHINSON CANCER CENTER	1100 FAIRVIEW AVE N	SEATTLE	WA	98109	KING	USA	Allergy and Infectious Diseases Research	008	7	8/9/2022	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$224,821
2022	2021	FRED HUTCHINSON CANCER CENTER	1100 FAIRVIEW AVE N	SEATTLE	WA	98109	KING	USA	Allergy and Infectious Diseases Research	009	7	8/11/2022	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$0
2022	2020	FRED HUTCHINSON CANCER RESEARCH CENTER	1100 FAIRVIEW AVE N J6-300	SEATTLE	WA	98109	KING	USA	Allergy and Infectious Diseases Research	001	5	4/6/2022	NON-COMPETING CONTINUATION	-$323,928
2022	2019	FRED HUTCHINSON CANCER RESEARCH CENTER	1100 FAIRVIEW AVE N J6-300	SEATTLE	WA	98109	KING	USA	Allergy and Infectious Diseases Research	000	4	4/6/2022	NON-COMPETING CONTINUATION	-$970
														Subtotal = $744,510

Issue Date FY: 2021 ( Subtotal = $323,615 )
2021	2021	FRED HUTCHINSON CANCER RESEARCH CENTER	1100 FAIRVIEW AVE N J6-300	SEATTLE	WA	98109	KING	USA	Allergy and Infectious Diseases Research	000	6	7/14/2021	COMPETING CONTINUATION	$323,615
														Subtotal = $323,615

Issue Date FY: 2020 ( Subtotal = $323,928 )
2020	2020	FRED HUTCHINSON CANCER RESEARCH CENTER	1100 FAIRVIEW AVE N J6-300	SEATTLE	WA	98109	KING	USA	Allergy and Infectious Diseases Research	002	5	7/22/2020	NON-COMPETING CONTINUATION	-$1,768
2020	2020	FRED HUTCHINSON CANCER RESEARCH CENTER	1100 FAIRVIEW AVE N J6-300	SEATTLE	WA	98109	KING	USA	Allergy and Infectious Diseases Research	001	5	7/8/2020	NON-COMPETING CONTINUATION	-$3,651
2020	2020	FRED HUTCHINSON CANCER RESEARCH CENTER	1100 FAIRVIEW AVE N J6-300	SEATTLE	WA	98109	KING	USA	Allergy and Infectious Diseases Research	000	5	5/5/2020	NON-COMPETING CONTINUATION	$329,347
														Subtotal = $323,928

Issue Date FY: 2019 ( Subtotal = $319,422 )
2019	2019	FRED HUTCHINSON CANCER RESEARCH CENTER	1100 FAIRVIEW AVE N J6-300	SEATTLE	WA	98109	KING	USA	Allergy and Infectious Diseases Research	000	4	5/3/2019	NON-COMPETING CONTINUATION	$319,422
														Subtotal = $319,422

Issue Date FY: 2018 ( Subtotal = $314,400 )
2018	2018	FRED HUTCHINSON CANCER RESEARCH CENTER	1100 FAIRVIEW AVE N J6-300	SEATTLE	WA	98109	KING	USA	Allergy and Infectious Diseases Research	000	3	6/27/2018	NON-COMPETING CONTINUATION	$314,400
														Subtotal = $314,400

Issue Date FY: 2017 ( Subtotal = $318,564 )
2017	2017	FRED HUTCHINSON CANCER RESEARCH CENTER	1100 FAIRVIEW AVE N J6-300	SEATTLE	WA	98109	KING	USA	Allergy and Infectious Diseases Research	000	1	4/13/2017	SUPPLEMENT FOR EXPANSION	$2,592
2017	2017	FRED HUTCHINSON CANCER RESEARCH CENTER	1100 FAIRVIEW AVE N J6-300	SEATTLE	WA	98109	KING	USA	Allergy and Infectious Diseases Research	001	2	7/11/2017	NON-COMPETING CONTINUATION	$315,972
														Subtotal = $318,564

Issue Date FY: 2016 ( Subtotal = $158,919 )
2016	2016	FRED HUTCHINSON CANCER RESEARCH CENTER	1100 FAIRVIEW AVE NO J6-330	SEATTLE	WA	98109	KING	USA	Allergy and Infectious Diseases Research	000	1	7/27/2016	NEW	$158,919
														Subtotal = $158,919

Grand Total All Awards = $3,335,838

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Training Program in Infectious Diseases in the Immunocompromised Host

Award Number: T32AI118690

ORGANIZATION: NATIONAL INSTITUTE OF ALLERGY & INFECTIOUS DISEASES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP

PERIOD OF PERFORMANCE START DATE: 08/01/2016

PERIOD OF PERFORMANCE END DATE: 07/31/2026

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