Saturday, February 14, 2026 2/14/2026

Characterization of amino acid transport- and signaling in the mosquito fat body

Award Number: SC1AI109055
ORGANIZATION: NATIONAL INSTITUTE OF ALLERGY & INFECTIOUS DISEASES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 07/09/2013
PERIOD OF PERFORMANCE END DATE: 06/30/2018

Group Awards By:

View Award Description

Characterization of amino acid transport- and signaling in the mosquito fat body - DESCRIPTION (provided by applicant): New insecticides with novel modes of action are urgently needed to improve public health in many countries around the world. This project addresses several important questions regarding nutrient transport and signaling pathways in the fat body of the yellow fever mosquito, Aedes aegypti. We will characterize the mode of action of two essential mosquito cationic amino acid transporters and test and improve promising compounds to inhibit cationic amino acid transport. We will complement these approaches with the development of an in silico mosquito fat body gene knowledge network designed to identify genes in the amino acid signaling and transport cascades downstream of cationic amino acid transporters. The proposed work will prove significant for human health through the significant gain of knowledge on amino acid transport and signaling in mosquitoes. Amino acid transport inhibitors have the potential to give rise to a new generation of public health insecticides. In addition, this study will expand our knowledge of the functional mechanism of cationic amino acid transporter in insects with implications for understanding essential amino acid transporters in humans and other model systems.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2019 ( Subtotal = -$5,778 )
2019	2016	NEW MEXICO STATE UNIVERSITY	1050 STEWART ST STE E1200	LAS CRUCES	NM	88003	DONA ANA	USA	Allergy and Infectious Diseases Research	000	4	1/3/2019	EXTENSION WITH OR WITHOUT FUNDS	-$5,778
														Subtotal = -$5,778

Issue Date FY: 2017 ( Subtotal = $0 )
2017	2016	NEW MEXICO STATE UNIVERSITY	1050 STEWART ST STE E1200	LAS CRUCES	NM	88003	DONA ANA	USA	Allergy and Infectious Diseases Research	001	4	1/23/2017	EXTENSION WITH OR WITHOUT FUNDS	$66,170
2017	2015	NEW MEXICO STATE UNIVERSITY	1050 STEWART ST STE E1200	LAS CRUCES	NM	88003	DONA ANA	USA	Allergy and Infectious Diseases Research	000	3	1/23/2017	NON-COMPETING CONTINUATION	-$66,170
														Subtotal = $0

Issue Date FY: 2016 ( Subtotal = $365,000 )
2016	2016	NEW MEXICO STATE UNIVERSITY	P.O. BOX 30001-MSC 3AA	LAS CRUCES	NM	88003	DONA ANA	USA	Allergy and Infectious Diseases Research	000	4	6/7/2016	EXTENSION WITH OR WITHOUT FUNDS	$365,000
														Subtotal = $365,000

Issue Date FY: 2015 ( Subtotal = $365,000 )
2015	2015	NEW MEXICO STATE UNIVERSITY	P.O. BOX 30001-MSC 3AA	LAS CRUCES	NM	88003	DONA ANA	USA	Allergy and Infectious Diseases Research	000	3	6/10/2015	NON-COMPETING CONTINUATION	$365,000
														Subtotal = $365,000

Issue Date FY: 2014 ( Subtotal = $365,000 )
2014	2014	NEW MEXICO STATE UNIVERSITY	P.O. BOX 30001-MSC 3AA	LAS CRUCES	NM	88003	DONA ANA	USA	Allergy and Infectious Diseases Research	000	2	6/17/2014	NON-COMPETING CONTINUATION	$365,000
														Subtotal = $365,000

Issue Date FY: 2013 ( Subtotal = $365,000 )
2013	2013	NEW MEXICO STATE UNIVERSITY	P.O. BOX 30001-MSC 3AA	LAS CRUCES	NM	88003	DONA ANA	USA	Allergy and Infectious Diseases Research	000	1	7/9/2013	NEW	$365,000
														Subtotal = $365,000

Grand Total All Awards = $1,454,222

Top

All Categories

About

Search

Reports

Data Submission

Award Information

Characterization of amino acid transport- and signaling in the mosquito fat body

Award Number: SC1AI109055

ORGANIZATION: NATIONAL INSTITUTE OF ALLERGY & INFECTIOUS DISEASES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 07/09/2013

PERIOD OF PERFORMANCE END DATE: 06/30/2018

Federal Websites

Department of Health & Human Services

HHS Operating Divisions

HHS Staff Divisions

Download A Document Viewer