Modernization of Anatomical Modeling Capabilities at UC Davis Core Facility - Project Abstract The Translating Engineering Advances to Medicine (TEAM) Lab, a core facility within the Biomedical Engineering Department at the University of California, Davis, seeks support to acquire the Stratasys J5 Digital Anatomy 3D Printer to modernize our shared-use biomedical research facility and overcome current limitations in the university's 3D printing technologies. The J5 Digital Anatomy Printer offers unique capabilities, including the ability to incorporate multiple materials into a single print to replicate the biomechanical properties and radiopacity of human tissue. Its advanced software comes pre-programmed with clinically validated presets that mimic a range of human tissues, while also allowing precise control over material composition and microstructures to replicate various tissue pathologies. By enhancing our ability to produce realistic anatomical models, the J5 printer will significantly elevate our research capabilities across multiple disciplines. It will facilitate groundbreaking studies in medical device development, surgical planning for rare and difficult-to-treat conditions, optimization of radiation dose delivery treatments, and more. Moreover, the ability to 3D print identical replicas of pathologies allows for more precise experimental testing and controls, reducing reliance on cadaver and animal models, which are costly, difficult to source, and generate biological waste. Acquiring the Stratasys J5 will enable the TEAM Lab to support new research initiatives currently constrained by technological limitations. By providing advanced simulations and realistic models, the printer will drive the development of new treatments for challenging disease states, leading to better patient care and outcomes. This enhancement aligns with UC Davis's mission to advance public health through pioneering research and innovation, ultimately fostering improved healthcare solutions and societal well-being. We plan to integrate the equipment into the TEAM Lab expansion, located at the UC Davis Sacramento Campus, is fully prepared for the new printer without requiring any site modifications. This expansion demonstrates the department’s and university's continued support for the TEAM Lab, operational since 2010 under the proposed PI’s management.