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AVIT24 System for Next-Generation Sequencing and Spatial MultiOmics to Advance Genomics Research at USC

Award Number: S10OD040590
ORGANIZATION: OFFICE OF THE DIRECTOR, NIH
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 07/01/2026
PERIOD OF PERFORMANCE END DATE: 06/30/2027

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AVIT24 System for Next-Generation Sequencing and Spatial MultiOmics to Advance Genomics Research at USC - Abstract: The University of South Carolina (USC) Functional Genomics Core (FGC), supported by the NIGMS-funded COBRE Center for Targeted Therapeutics, offers comprehensive genomics, transcriptomics, and epigenomics services to a diverse research community. This includes NIH- and NSF-funded investigators across the USC Columbia campus, regional campuses, the state of South Carolina, and out-of-state collaborators. The Core currently depends on an aging Illumina NextSeq 500 platform for next-generation sequencing (NGS), which presents significant limitations in throughput, operational efficiency, and cost-effectiveness. To address these challenges and accommodate the growing demand for high-throughput and spatially resolved molecular profiling, we propose acquiring the Element Biosciences AVITI24 system. This advanced platform significantly enhances data quality, operational cost, and scalability for both small and large projects. Uniquely among NGS systems, the AVITI24 integrates spatial transcriptomics and proteomics capabilities, enabling simultaneous spatial and sequence-based analyses within a single instrument. This transformative capability will broaden access to cutting-edge spatial multiomics technologies for a wide range of users, including early-stage investigators and underrepresented researchers, while greatly improving the throughput, precision, and affordability of genomic services. The acquisition of the AVITI24 will modernize the FGC’s sequencing infrastructure, support interdisciplinary biomedical research programs, and allow NIH-funded investigators at USC and in South Carolina to access new technologies. Overall, this instrument will significantly and sustainably enhance the productivity and competitiveness of the USC research community and regional FGC partners.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = $395,000 )
2026	2026	UNIVERSITY OF SOUTH CAROLINA	1600 HAMPTON ST	COLUMBIA	SC	29208	RICHLAND	USA	Research Infrastructure Programs	000	1	7/3/2026	NEW	$395,000
														Subtotal = $395,000

Grand Total All Awards = $395,000

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AVIT24 System for Next-Generation Sequencing and Spatial MultiOmics to Advance Genomics Research at USC

Award Number: S10OD040590

ORGANIZATION: OFFICE OF THE DIRECTOR, NIH

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 07/01/2026

PERIOD OF PERFORMANCE END DATE: 06/30/2027

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