Official websites use .gov

A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS

A lock ( 🔒 ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

Need Help

Emotion Reactivity, Cognitive Reappraisal, and Suicidal Ideation In Middle-aged and Older Adults at High Suicide Risk

Award Number: RF1MH134006
ORGANIZATION: NATIONAL INSTITUTE OF MENTAL HEALTH
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 07/12/2024
PERIOD OF PERFORMANCE END DATE: 04/30/2029

Group Awards By:

View Award Description

Emotion Reactivity, Cognitive Reappraisal, and Suicidal Ideation In Middle-aged and Older Adults at High Suicide Risk - ABSTRACT The goal of this project is to evaluate the temporal and predictive association of emotion reactivity (ER) and cognitive reappraisal (CR) (a well-studied emotion regulation strategy) with intensity and duration of suicidal ideation (SI) in middle-aged and older adults following their discharge from a suicide-related hospitalization, a period of high suicide risk. Our preliminary Event Related Potential (ERP) and self-reported affect data on middle-aged : a) increased ER and reduced CR at Discharge were independently associated with increased intensity and longer duration of suicidal ideation at Week 6; and b) patients with combined high ER and low CR at Discharge had higher intensity and longer duration of suicidal ideation at Week 6 than the rest of the patients. and older adults (N=36) who were hospitalized for suicidality demonstrated that We will recruit 162 middle-aged and older adults (40-90 years old) who have been hospitalized for suicidal ideation or suicidal behavior [Columbia Suicide Severity Rating Scale (C-SSRS) at Admission > 1, i.e., 1=Wishes to be Dead]. We will follow the participants for 6 months after discharge. Suicidal ideation and behavior will be measured weekly through an interviewer-administered instrument (C-SSRS). ER and CR will be assessed with: 1) electrocortical measures (Late Positive Potential) and self-reported affect during an emotion reactivity and regulation EEG task (primary measures), and 2) the Emotion Regulation Questionnaire and the Perth Emotional Reactivity Scale (secondary measures). Assessments will be conducted at Admission (without EEG), Discharge, and at Weeks 6, 12, 18, and 24. 1. Examine the Independent Effects of ER and CR on Intensity and Duration of SI. 2. Examine the Combined Effects of ER and CR on Intensity and Duration of SI. Exploratory Analyses: 1. Examine whether demographic variables, discharge clinical characteristics, rehospitalization, medical comorbidities, and other suicide risk factors moderate the relationship of ER and CR with suicidal ideation. 2. Examine association of the longitudinal profile of ER and CR with the longitudinal profile of intensity and duration of suicidal ideation. Primary Aims: This is the first study to examine the predictive relationship of ER and CR with suicidal ideation in middle-aged and older adults at high suicide risk. Understanding this relationship will help identify: a) mechanisms which increase suicidal ideation, and b) subgroups of patients at increased suicide risk. Consistent with the concept of “Precision Medicine”, the findings may contribute to the development of personalized psychosocial interventions for this population.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = $2,020,459 )
2026	2026	WEILL MEDICAL COLLEGE OF CORNELL UNIVERSITY	575 LEXINGTON AVE FL 9	NEW YORK	NY	10022	NEW YORK	USA	Mental Health Research Grants	000	3	5/11/2026	EXTENSION WITH OR WITHOUT FUNDS	$2,020,459
														Subtotal = $2,020,459

Grand Total All Awards = $2,020,459

Top

All Categories

About

Search

Reports

Data Submission

Award Information

Emotion Reactivity, Cognitive Reappraisal, and Suicidal Ideation In Middle-aged and Older Adults at High Suicide Risk

Award Number: RF1MH134006

ORGANIZATION: NATIONAL INSTITUTE OF MENTAL HEALTH

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 07/12/2024

PERIOD OF PERFORMANCE END DATE: 04/30/2029

Federal Websites

Department of Health & Human Services

HHS Operating Divisions

HHS Staff Divisions

Download A Document Viewer