Official websites use .gov

A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS

A lock ( 🔒 ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

Need Help

Assessing Everyday Function In Older Adults With The Virtual Kitchen

Award Number: RF1AG062503
ORGANIZATION: NATIONAL INSTITUTE ON AGING
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 02/01/2020
PERIOD OF PERFORMANCE END DATE: 04/30/2030

Group Awards By:

View Award Description

Assessing Everyday Function In Older Adults With The Virtual Kitchen - Project Summary/Abstract Mild functional difficulties are a strong predictor of future cognitive decline in older adults across the spectrum from healthy cognition to mild cognitive impairment (MCI) and precede impairment on traditional cognitive tests. Functional ability level is a criterion that distinguishes clinical stages of Alzheimer’s disease (AD) and AD related dementias (AD/ADRD) and is a highly meaningful outcome to patients and families in clinical trials. However, the current conventional approach to functional assessment includes questionnaires, which are useful and highly efficient, but often are atheoretical and limited by methodological drawbacks, including a range of biases, recall failures, and/or the availability of a knowledgeable informant. To address these needs and gaps in our original R01 proposal, we developed and validated an efficient performance-based measure called the Virtual Kitchen Challenge-Version 2 (VKC-2). The goal of this renewal is to evaluate the predictive validity of the VKC- 2 after 3-5 years, further develop the efficiency of the VKC in a new version with automated administration (VKC-3) and test a comprehensive framework for functional assessment using novel digital tools, such as smartphone digital phenotyping and ecological momentary assessment (EMA). This renewal includes three aims. Aim 1: Test the hypothesis that baseline VKC-2 automated scores will significantly predict cognitive abilities after 3-5 years (predictive validity). Our VKC-2 validation cohort will be re-evaluated after 3-5 years, and regression models with baseline VKC-2 scores as predictors and conventional cognitive measures as outcomes will be performed. A new version of the VKC with a participant-driven interface and no examiner input also will be piloted to further increase test efficiency. Aim 2: Test the hypothesis that VKC-2 automated scores will significantly predict everyday behaviors and routines (i.e., functional performance). Participants (N=300) from Aim 1 will download the open-source, mindLAMP app on their own smartphone to collect GPS sensor data and daily EMA responses about participants’ daily activities during a 4-week period. Two sets of regression models will include baseline VKC-2 (from the original R01) or concurrent VKC-3 scores as predictors and GPS/EMA measures of activity and activity variability as outcomes. Aim 3: Test the hypothesis that economic resources, participant motivation, and participant physical abilities will moderate the relations between functional capacity (VKC-2) and functional performance (GPS, EMA). Participants will complete validated questionnaires of economic resources, trait motivation, and physical abilities. Regression models will test moderation of the relation between VKC-2 scores and measures of functional performance (GPS, EMA). The proposed aims seek to validate a fully automated VKC-3 and a comprehensive framework for understanding everyday function, which together have the potential to address important functional assessment challenges in multiple contexts, including screening older adults for risk of functional decline and as a function endpoint in clinical trials of AD/ADRD treatments.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = $2,518,803 )
2026	2026	TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION	1805 N BROAD ST	PHILADELPHIA	PA	19122	PHILADELPHIA	USA	Aging Research	000	6	5/7/2026	COMPETING CONTINUATION	$2,518,803
														Subtotal = $2,518,803

Grand Total All Awards = $2,518,803

Top

All Categories

About

Search

Reports

Data Submission

Award Information

Assessing Everyday Function In Older Adults With The Virtual Kitchen

Award Number: RF1AG062503

ORGANIZATION: NATIONAL INSTITUTE ON AGING

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 02/01/2020

PERIOD OF PERFORMANCE END DATE: 04/30/2030

Federal Websites

Department of Health & Human Services

HHS Operating Divisions

HHS Staff Divisions

Download A Document Viewer