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Targeting Minority Stressors to Improve Eating Disorder Symptoms in Sexual Minority Individuals with Eating Disorders

Award Number: R61MH133710
ORGANIZATION: NATIONAL INSTITUTE OF MENTAL HEALTH
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 08/01/2024
PERIOD OF PERFORMANCE END DATE: 10/31/2026

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Targeting Minority Stressors to Improve Eating Disorder Symptoms in Sexual Minority Individuals with Eating Disorders - Modified Project Summary/Abstract Section Eating disorders are one of the deadliest psychiatric disorders and are associated with high economic burden and numerous physical health consequences. One group at significantly increased risk for eating disorders is sexual minority (SM) individuals. Indeed, nationally representative data in the United States supports that SM adults have a 2-3-fold increased risk of developing an eating disorder compared to their non-SM peers. Critically, these mental health disparities have persisted during the past decade, with no signs of attenuating, making SM individuals one of the highest-risk groups for eating disorders. Risk is elevated in SM individuals due to chronic stressors and subsequent SM stress reactions (e.g., internalized stigma, low SM-stress coping self-efficacy). While SM individuals are seeking eating disorder treatment at increasing rates compared to non-SM peers, current treatments do not incorporate distinct SM identity-related stress processes that increase and maintain eating disorder symptoms in SM individuals. Further, SM individuals are more likely to drop out of existing eating disorder treatments compared to their non-SM peers. This suggests that identity-affirming treatments that address the unique needs of SM individuals with eating disorders could reduce barriers to treatment and treatment dropout in a vulnerable group. Given this crucial gap in the literature, the proposed study will refine and test an innovative virtually delivered treatment that integrates evidence-based care for eating disorders with SM-affirmative treatment (Promoting Resilience to Improve Disordered Eating; PRIDE) designed to target distinct identity-related stress processes (e.g., reductions in internalized stigma and increases in SM-stress coping self-efficacy) that theoretically underlie increased risk for eating disorders in SM individuals. If PRIDE displays a clinically meaningful effect on the purported targets (i.e., reduction in internalized stigma and increases in SM-stress coping self-efficacy) through 6-month follow-up during the open-phase trial (R61 phase; n = 30) and is feasible and acceptable, we will subsequently move to the R33 phase. In the R33 phase, we will conduct a pilot randomized controlled trial in 160 SM adults with eating disorders comparing PRIDE to supportive treatment to assess preliminary efficacy through 12-month follow-up. During the randomized controlled trial, we will also evaluate the mechanisms of action of the PRIDE treatment (e.g., reductions in internalized stigma and increases in SM-stress coping self-efficacy) through longitudinal analysis. The proposed project has substantial public health significance as SM adults are one of the most vulnerable groups for eating disorders. Given the virtual nature of PRIDE, this treatment has a high potential for wide dissemination and to reduce the public health impact of eating disorders in a vulnerable group.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = $0 )
2026	2025	AUBURN UNIVERSITY	321-A INGRAM HALL	AUBURN	AL	36849	LEE	USA	Mental Health Research Grants	000	2	12/10/2025	OTHER REVISION	$0
														Subtotal = $0

Issue Date FY: 2025 ( Subtotal = $965,842 )
2025	2025	AUBURN UNIVERSITY	321-A INGRAM HALL	AUBURN	AL	36849	LEE	USA	Mental Health Research Grants	002	2	8/8/2025	NON-COMPETING CONTINUATION	$965,842
2025	2024	AUBURN UNIVERSITY	321-A INGRAM HALL	AUBURN	AL	36849	LEE	USA	Mental Health Research Grants	000	1	3/21/2025	TERMINATION	$0
2025	2024	AUBURN UNIVERSITY	321-A INGRAM HALL	AUBURN	AL	36849	LEE	USA	Mental Health Research Grants	001	1	7/7/2025	OTHER REVISION	$0
														Subtotal = $965,842

Issue Date FY: 2024 ( Subtotal = $978,986 )
2024	2024	AUBURN UNIVERSITY	321-A INGRAM HALL	AUBURN	AL	36849	LEE	USA	Mental Health Research Grants	000	1	7/29/2024	NEW	$978,986
														Subtotal = $978,986

Grand Total All Awards = $1,944,828

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Targeting Minority Stressors to Improve Eating Disorder Symptoms in Sexual Minority Individuals with Eating Disorders

Award Number: R61MH133710

ORGANIZATION: NATIONAL INSTITUTE OF MENTAL HEALTH

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 08/01/2024

PERIOD OF PERFORMANCE END DATE: 10/31/2026

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