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Rapid and Simple Paper Strip Test for the Multiplexed Detection of Gastrointestinal Pathogens at the Point-of-Need

Award Number: R44TR001912
ORGANIZATION: NATIONAL CENTER FOR ADVANCING TRANSLATIONAL SCIENCES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 11/01/2020
PERIOD OF PERFORMANCE END DATE: 07/31/2022

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Rapid and Simple Paper Strip Test for the Multiplexed Detection of Gastrointestinal Pathogens at the Point-of-Need - PROJECT SUMMARY GoDx, Inc. has been developing a prototype multiplexed paper strip device for the detection of the DNA and RNA of gastrointestinal pathogens at the point-of-need in < 30 minutes with funding from the NCATS SBIR parent grant TR 001912. We have used the same platform technology we are developing in the parent grant to develop a rapid (<30 minute), low-cost and instrument-free paper strip test for SARS-CoV-2 that can be performed in a wide range of settings. Our tests are more sensitive than the antigen tests since the RNA of the virus are exponentially amplified. The value proposition of this test is that it is fast and readily available to the patient (30 minutes at the doctor's office with a simple, physician's office laboratory vs 2-3 days sending samples to a laboratory) which allows faster isolation and treatment of the patient. Our test will also be valuable in laboratories and hospitals with limited resources in the developed and the developing world that do not have an RT-PCR instrument to test for coronavirus. We propose the commercialization of a simple, rapid, ow-cost and instrument-free test to detect SARS-CoV-2. We will perform the analytical and clinical validation required for the FDA Emergency Use Authorization (EUA). We will also manufacture and commercialize our test.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2023 ( Subtotal = -$27,676 )
2023	2021	GODX INC.	510 CHARMANY DR STE 265	MADISON	WI	53719	DANE	USA	National Center for Advancing Translational Sciences	000	3	2/14/2023	SUPPLEMENT FOR EXPANSION	-$27,676
														Subtotal = -$27,676

Issue Date FY: 2021 ( Subtotal = $597,814 )
2021	2021	GODX INC.	510 CHARMANY DR STE 265	MADISON	WI	53719	DANE	USA	National Center for Advancing Translational Sciences	002	3	6/10/2021	SUPPLEMENT FOR EXPANSION	$0
2021	2021	GODX INC.	510 CHARMANY DR STE 265	MADISON	WI	53719	DANE	USA	National Center for Advancing Translational Sciences	000	3	10/31/2020	SUPPLEMENT FOR EXPANSION	$597,814
2021	2019	GODX INC.	510 CHARMANY DR STE 265	MADISON	WI	53719	DANE	USA	National Center for Advancing Translational Sciences	001	3	6/10/2021	NON-COMPETING CONTINUATION	$0
														Subtotal = $597,814

Issue Date FY: 2020 ( Subtotal = $432,593 )
2020	2020	GODX INC.	510 CHARMANY DR STE 257	MADISON	WI	53719	DANE	USA	National Center for Advancing Translational Sciences	001	3	12/15/2019	SUPPLEMENT FOR EXPANSION	$239,594
2020	2020	GODX INC.	510 CHARMANY DR STE 265	MADISON	WI	53719	DANE	USA	National Center for Advancing Translational Sciences	002	3	4/22/2020	SUPPLEMENT FOR EXPANSION	$192,999
2020	2019	GODX INC.	510 CHARMANY DR STE 257	MADISON	WI	53719	DANE	USA	National Center for Advancing Translational Sciences	000	3	11/13/2019	NON-COMPETING CONTINUATION	$0
														Subtotal = $432,593

Issue Date FY: 2019 ( Subtotal = $1,204,574 )
2019	2019	GODX INC.	510 CHARMANY DR STE 257	MADISON	WI	53719	DANE	USA	National Center for Advancing Translational Sciences	001	3	7/10/2019	NON-COMPETING CONTINUATION	$1,116,150
2019	2019	GODX INC.	510 CHARMANY DR STE 257	MADISON	WI	53719	DANE	USA	National Center for Advancing Translational Sciences	000	2	1/28/2019	SUPPLEMENT FOR EXPANSION	$88,424
														Subtotal = $1,204,574

Issue Date FY: 2018 ( Subtotal = $966,680 )
2018	2018	GODX INC.	510 CHARMANY DR STE 257	MADISON	WI	53719	DANE	USA	National Center for Advancing Translational Sciences	000	2	7/17/2018	COMPETING CONTINUATION	$966,680
														Subtotal = $966,680

Grand Total All Awards = $3,173,985

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Rapid and Simple Paper Strip Test for the Multiplexed Detection of Gastrointestinal Pathogens at the Point-of-Need

Award Number: R44TR001912

ORGANIZATION: NATIONAL CENTER FOR ADVANCING TRANSLATIONAL SCIENCES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 11/01/2020

PERIOD OF PERFORMANCE END DATE: 07/31/2022

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