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NOVEL RF COILS FOR IMAGING NEONATES

Award Number: R44MH070709
ORGANIZATION: NATIONAL INSTITUTE OF MENTAL HEALTH
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 09/01/1999
PERIOD OF PERFORMANCE END DATE: 08/31/2005

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NOVEL RF COILS FOR IMAGING NEONATES - DESCRIPTION (provided by applicant): A long-term goal is to permit routine magnetic resonance examinations of critically ill pre and term neonates. We intend to accomplish this by adapting the radio-frequency (RF) coils developed in this project to the stand-alone incubator system developed elsewhere. More specifically, this proposal will develop high performance RF coils to enable high resolution imaging of the brain, spine and heart of sick pre and term neonates. Our coils will be interfaced to General Electric (Signa), Siemens (Symphony, Sonata) and Philips (Eclipse) 1.5T and GE 3T Magnetic Resonance systems. All of the RF coils developed will be systematically evaluated with phantoms and compared to existing devices. This will be followed by clinical verifications on a small number of ill patients with the assistance of our collaborators from the neonatology and radiology departments, on the 1.5 and 3T GE Signa at the Children's Hospital of Los Angeles and 1.5T Philips Eclipse MRI at the MetroHealth Medical Center. In addition, specific absorption rate (SAR) measurements will be made for our transmit/receive coils using the energy per pulse method at 1.5T and 3T. With the incubator system, sick neonates can be safely transported and scanned using MR. High quality data obtained with high signal-to-noise (S/N) custom coils may assist in the prognosis/diagnosis of illnesses which in turn may lead to prompt clinical (surgical, pharmaceutical) interventions which in turn may save many precious lives. This we believe will be a significant benefit to mankind. The significance of the work proposed is paramount.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2004 ( Subtotal = $607,804 )
2004	2004	ADVANCED IMAGING RESEARCH, INC	4700 LAKESIDE AVE, SUITE 400	CLEVELAND	OH	44114	CUYAHOGA	USA	Mental Health Research Grants	000	3	7/26/2004	NON-COMPETING CONTINUATION	$607,804
														Subtotal = $607,804

Issue Date FY: 2003 ( Subtotal = $721,158 )
2003	2003	ADVANCED IMAGING RESEARCH, INC	4700 LAKESIDE AVE, SUITE 400	CLEVELAND	OH	44114	CUYAHOGA	USA	Mental Health Research Grants	000	2	9/30/2003	OTHER REVISION	$721,158
														Subtotal = $721,158

Grand Total All Awards = $1,328,962

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NOVEL RF COILS FOR IMAGING NEONATES

Award Number: R44MH070709

ORGANIZATION: NATIONAL INSTITUTE OF MENTAL HEALTH

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 09/01/1999

PERIOD OF PERFORMANCE END DATE: 08/31/2005

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