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The Blackfynn Platform for Rapid Data Integration and Collaboration

Award Number: R44DA044929
ORGANIZATION: NATIONAL INSTITUTE ON DRUG ABUSE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 05/01/2017
PERIOD OF PERFORMANCE END DATE: 04/30/2019

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The Blackfynn Platform for Rapid Data Integration and Collaboration - Summary One in seven people worldwide suffers from a brain disorder, e.g., epilepsy, Parkinson's, stroke, or dementia. Development of future treatments depends on improving our understanding of brain function and disease, and validating new treatments critically depends on identifying the underlying biomarkers associated with different conditions. Biomarker discovery requires volume, quality, richness, and diversity of data. This Direct-to-Phase II project extends Blackfynn's cloud data management platform for team science, in order to support interactive data curation and integration and to facilitate biomarker discovery. Our first technical aim develops tools to help select, curate, assess, and regularize datasets: we develop novel “live” query capabilities to ensure users discover relevant data, develop mechanisms for using data's provenance to decide on trustworthiness, and build tools for mapping fields to common data elements. These capabilities address the critical, under-served problem of selecting the data to analyze. Our second technical aim develops techniques for incorporating algorithms to link and co-register across multi-modal data and metadata. Using ranking and machine learning, we can incorporate and combine state-of-the-art algorithms for finding data relationships, and we can link to remote data sources. These capabilities enable scientists to analyze richer datasets with multiple data modalities and properties – thus enabling them to discover more complex correlations and biomarkers. In our third aim, Blackfynn's new technical capabilities will be applied to challenges faced by Blackfynn partners, including problems assessing trustworthiness of data annotations, conducting image analysis, modeling epileptic networks, and identifying biomarkers for neuro-oncology indications. As part of this validation we will also develop HIPAA-compliant mechanisms for working with protected and de-identified data together. Together, these three thrusts will ensure that development of the Blackfynn platform results in tools and technologies that meaningfully accelerate scientific understanding and discovery over rich and complex data, leading to improved treatments for neurologic disease.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2020 ( Subtotal = $0 )
2020	2018	BLACKFYNN INC.	1218 CHESTNUT ST., 8TH FLR	PHILADELPHIA	PA	19107	PHILADELPHIA	USA	Drug Use and Addiction Research Programs	000	2	11/1/2019	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2018 ( Subtotal = $696,602 )
2018	2018	BLACKFYNN INC.	121 S BROAD STREET, SUITE 510	PHILADELPHIA	PA	19107	PHILADELPHIA	USA	Drug Use and Addiction Research Programs	000	2	3/23/2018	NON-COMPETING CONTINUATION	$696,602
														Subtotal = $696,602

Issue Date FY: 2017 ( Subtotal = $652,921 )
2017	2017	BLACKFYNN INC.	121 S BROAD STREET	PHILADELPHIA	PA	19107	PHILADELPHIA	USA	Drug Use and Addiction Research Programs	000	1	4/7/2017	NEW	$652,921
														Subtotal = $652,921

Grand Total All Awards = $1,349,523

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The Blackfynn Platform for Rapid Data Integration and Collaboration

Award Number: R44DA044929

ORGANIZATION: NATIONAL INSTITUTE ON DRUG ABUSE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 05/01/2017

PERIOD OF PERFORMANCE END DATE: 04/30/2019

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