Abstract
Adolescents in the juvenile justice system demonstrate very high rates of tobacco, alcohol, and other drug use
(ATOD), with rates that are estimated to be three times higher than non-justice-involved youth. Substance-
abusing youth – especially those who are involved in the juvenile justice system – are at higher risk than
nonusers for mental health problems, including depression, conduct problems, personality disorders, suicidal
thoughts, attempted suicide, and completed suicide. Additionally, there is evidence of detrimental effects on
brain development and stress responsive neurobiological systems from substance abuse. There is growing
evidence that interventions based on mindfulness have been an efficacious intervention for a variety of
problems, including substance use among adolescents. We propose to adapt and test the feasibility and
efficacy of a smart phone application (app) intervention prototype that would help adolescent substance users
reduce or quit their substance use. The program, entitled Rewire, is based on the primary substance use
cessation components tested in our previous work with juvenile justice-involved adolescents and on
intervention components shown to be central to smoking cessation, and applies a mindfulness approach as the
guiding framework for the intervention. The twelve module program, which includes 24 components (12
teaching components and 12 practice components) for each module, will be evaluated with 380 high risk
adolescents that are involved in the juvenile justice system. The proposed program will be the only
mindfulness-based mobile app specifically targeting the reduction or cessation of adolescent substance use;
there is high level of need for the program both as an adjunct to existing treatments and for use in the juvenile
justice system. Our research and development team has extensive experience in working with adolescents that
use ATOD, and we have been using mindfulness as the framework for in-person interventions with youth in the
juvenile justice system as well as through the Phase I development of the Rewire app. The research team will
partner with Twenty Ideas, who has extensive experience in the development of mobile apps for smartphones,
and who was the software development company for Phase I. We will assess navigation and usability with high
risk adolescents who are currently reporting substance use. Additional pilot testing will be used to guide
development of the Rewire app for evaluation. The evaluation study will involve having 380 youth ages 13-18
involved in the juvenile justice system use the app for 1 month and complete baseline, 1- and 3-month follow-
up. Usability data, program engagement, changes in attitudes, emotions and behaviors, and self-reported
substance use will be used to determine the efficacy of the Rewire mobile app.