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Spatial genomics analysis of tumor samples

Award Number: R44CA285121
ORGANIZATION: NATIONAL CANCER INSTITUTE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 09/01/2023
PERIOD OF PERFORMANCE END DATE: 08/31/2025

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Spatial genomics analysis of tumor samples - SUMMARY Imaging the tumor microenvironment (TME) is key to understanding tumor growth, disease progression and therapy options. The TME often consists of a complex neighborhood of diverse populations of immune cells, fibroblasts, and tumors cells. Little is known about the “geography” of the tumors and the spatial organization of the distinct cell types. The ability to rapidly identify different cell types and tumor subtypes using molecular markers will be transformative for cancer diagnostics. At Spatial Genomics, we are commercializing technology that allows transcript profiling in tumor samples. With this technology, cell types in situ and spatial organizations can be directly identified and visualized in tumor tissue slices. These capabilities provide a powerful tool for examining the different cell types and their interactions in the tumor microenvironment. In this proposal, we will develop the reagents, instrumentation, and the associated software that will allow researchers to perform spatial mapping experiments in tumor slices.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = $0 )
2026	2024	SPATIAL GENOMICS, INC.	145 VISTA AVE STE 111	PASADENA	CA	91107	LOS ANGELES	USA	Cancer Biology Research	000	2	1/6/2026	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2024 ( Subtotal = $998,481 )
2024	2024	SPATIAL GENOMICS, INC.	145 VISTA AVE STE 111	PASADENA	CA	91107	LOS ANGELES	USA	Cancer Biology Research	000	2	8/5/2024	NON-COMPETING CONTINUATION	$998,481
														Subtotal = $998,481

Issue Date FY: 2023 ( Subtotal = $998,481 )
2023	2023	SPATIAL GENOMICS, INC.	145 VISTA AVE STE 111	PASADENA	CA	91107	LOS ANGELES	USA	Cancer Biology Research	000	1	9/1/2023	NEW	$998,481
														Subtotal = $998,481

Grand Total All Awards = $1,996,962

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Spatial genomics analysis of tumor samples

Award Number: R44CA285121

ORGANIZATION: NATIONAL CANCER INSTITUTE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 09/01/2023

PERIOD OF PERFORMANCE END DATE: 08/31/2025

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