Tuesday, February 17, 2026 2/17/2026

Sedationless Multi-View High-Resolution Endoscopy

Award Number: R44CA265758
ORGANIZATION: NATIONAL CANCER INSTITUTE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 08/10/2021
PERIOD OF PERFORMANCE END DATE: 07/31/2025

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Sedationless Multi-View High-Resolution Endoscopy - Abstract An upper endoscope is designed for the endoscopic evaluation of the esophagus, stomach and duodenum, however, of the six-million upper endoscopies performed annually in the US, about half are for the disorders of the esophagus alone, where it can be argued that a full endoscopy of these three organs is not necessary in many, particularly since the procedure requires sedation with its associated risk and expense. Sedation adds to the risk of complications and increases expense. The high cost also adds to healthcare disparities. We propose a safer, cost-effective and convenient alternative by developing a market-ready high- resolution endoscopic tool that will allow patients to have an un-sedated inspection of the esophagus, affordably and in the convenience of their doctor’s office. Our device would be most effective in the evaluation of patients with gastro-esophageal reflux symptoms and to screen for its complication, Barrett’s esophagus, both of which are highly prevalent. Since Barrett’s esophagus is found in about 15% of patients with chronic reflux symptoms, visually confirming its absence will allow 85% of patients to avoid a standard endoscopy with biopsies which would be needed for only 15% of patients. It will also allow screening for esophageal varices in patients with chronic liver disease and allow widespread affordable screening for squamous cell cancer in other parts of the world. We have developed a reusable tethered capsule with a forward- and rear- facing cameras, capable of white- light and narrow-band imaging with a degree of resolution beyond the reach of current endoscopes. The compact capsule is smaller than current wireless capsules and was developed after consultations with physicians, marketing and sales personnel in endoscopy. Development was guided by meetings with the FDA, which recommended that we proceed with bench tests followed by a clinical evaluation. The clinical study will be led by an expert researcher in esophageal disease and endoscopy. We are collaborating with a marketing group known for successfully launching gastrointestinal endoscopic devices in the US and overseas. Our reusable high-resolution imaging device will allow the esophagus and proximal stomach to be examined easily, safely and affordably (at a fraction of the cost of a standard upper endoscopy) for a transformational effect on endoscopic practice. It will help detect common diseases in more people, prevent cancer and save lives.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = -$202,121 )
2026	2023	OMNISCIENT IMAGING INC	1661 N SWAN RD	TUCSON	AZ	85712	PIMA	USA	Cancer Detection and Diagnosis Research	000	3	11/21/2025	NON-COMPETING CONTINUATION	-$202,121
														Subtotal = -$202,121

Issue Date FY: 2023 ( Subtotal = $918,003 )
2023	2023	OMNISCIENT IMAGING, INC.	1661 N SWAN RD STE 300	TUCSON	AZ	85712	PIMA	USA	Cancer Detection and Diagnosis Research	000	3	8/30/2023	NON-COMPETING CONTINUATION	$918,003
														Subtotal = $918,003

Issue Date FY: 2022 ( Subtotal = $1,031,682 )
2022	2022	OMNISCIENT IMAGING, INC.	1661 N SWAN RD STE 300	TUCSON	AZ	85712	PIMA	USA	Cancer Detection and Diagnosis Research	001	2	7/21/2022	EXTENSION WITH OR WITHOUT FUNDS	$1,031,682
2022	2021	OMNISCIENT IMAGING, INC.	1661 N SWAN RD STE 300	TUCSON	AZ	85712	PIMA	USA	Cancer Detection and Diagnosis Research	000	1	7/5/2022	NEW	$0
														Subtotal = $1,031,682

Issue Date FY: 2021 ( Subtotal = $396,406 )
2021	2021	OMNISCIENT IMAGING, INC.	6463 E VIA AMABLE	TUCSON	AZ	85750	PIMA	USA	Cancer Detection and Diagnosis Research	000	1	8/10/2021	NEW	$396,406
														Subtotal = $396,406

Grand Total All Awards = $2,143,970

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Sedationless Multi-View High-Resolution Endoscopy

Award Number: R44CA265758

ORGANIZATION: NATIONAL CANCER INSTITUTE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 08/10/2021

PERIOD OF PERFORMANCE END DATE: 07/31/2025

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