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Stable Targeting Assistance for Ultrasound-Based Instrument Guidance

Award Number: R44CA168127
ORGANIZATION: NATIONAL CANCER INSTITUTE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 02/01/2012
PERIOD OF PERFORMANCE END DATE: 03/31/2017

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Stable Targeting Assistance for Ultrasound-Based Instrument Guidance - ¿ DESCRIPTION (provided by applicant): Transcutaneous ultrasound imaging is becoming an increasingly widespread tool across a wide range of clinical specialties, partly encouraged or even mandated by federal guidelines. However, the imaging skill and manual dexterity necessary to perform these procedures is not easy to acquire, and pose a significant challenge to efficient and effective procedures for many clinicians. The proposed project aims to improve the ease of use and the effectiveness of interventional ultrasound by providing a novel feedback method that will assist operators to maintain correct probe and needle pose relative to a clinical target. The proposed method is a form of image stabilization, and relies on the development of on- probe optical tracking of probe motion relative to the patient body, as well as subsurface tracking of a clinical target in ultrasound images. By combining these two information sources, an estimate of the optimal probe movement to maintain the target in view can be computed. Feedback to the user can then be delivered through auditory or visual channels, but importantly also through a novel haptic feedback mechanism that will be developed and tested in this project. A successful outcome will substantially increase the availability of such procedures by allowing a wide range of clinicians of all skill levels achieve satisfying results in terms of accuracy and speed. Our work during this Phase II project will be in close collaboration with anesthesiologists who represent a prime user group for our improved feedback system. They and other clinicians will provide design inputs at the beginning and throughout the proposed work. We expect to develop a pre-market prototype and to distribute this system to a wider range of physicians in the course of the project.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2017 ( Subtotal = $0 )
2017	2016	CLEAR GUIDE MEDICAL, INC.	3600 CLIPPER MILL RD STE 400	BALTIMORE	MD	21211	BALTIMORE CITY	USA	Cancer Detection and Diagnosis Research	001	3	2/17/2017	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$218,082
2017	2016	CLEAR GUIDE MEDICAL, INC.	3600 CLIPPER MILL RD STE 400	BALTIMORE	MD	21211	BALTIMORE CITY	USA	Cancer Detection and Diagnosis Research	002	3	9/21/2017	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$0
2017	2015	CLEAR GUIDE MEDICAL, INC.	3600 CLIPPER MILL RD STE 400	BALTIMORE	MD	21211	BALTIMORE CITY	USA	Cancer Detection and Diagnosis Research	000	2	2/17/2017	COMPETING CONTINUATION	-$218,082
														Subtotal = $0

Issue Date FY: 2016 ( Subtotal = $749,293 )
2016	2016	CLEAR GUIDE MEDICAL INC	3600 CLIPPER MILL ROAD	BALTIMORE	MD	21211	BALTIMORE CITY	USA	Cancer Detection and Diagnosis Research	000	3	6/2/2016	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$749,293
														Subtotal = $749,293

Issue Date FY: 2015 ( Subtotal = $679,123 )
2015	2015	CLEAR GUIDE MEDICAL LLC	40 WARRENTON ROAD	BALTIMORE	MD	21210	BALTIMORE CITY	USA	Cancer Detection and Diagnosis Research	000	2	4/13/2015	COMPETING CONTINUATION	$679,123
														Subtotal = $679,123

Grand Total All Awards = $1,428,416

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Stable Targeting Assistance for Ultrasound-Based Instrument Guidance

Award Number: R44CA168127

ORGANIZATION: NATIONAL CANCER INSTITUTE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 02/01/2012

PERIOD OF PERFORMANCE END DATE: 03/31/2017

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