Sunday, October 26, 2025 10/26/2025

Controlled Release Eczema Bandage (CREB)

Award Number: R44AT011486
ORGANIZATION: CENTER FOR DRUG EVALUATION AND RESEARCH, NIH
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 08/01/2021
PERIOD OF PERFORMANCE END DATE: 08/31/2026

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Controlled Release Eczema Bandage (CREB) - Project Summary/Abstract: CFD Research Corporation has developed a novel microbiome-balancing wet wrap therapy for atopic dermatitis based on a natural compound with unique physicochemical and pharmacological activities. The compound has been found to have an interleukin-based immune modulatory effect that helps soothe the flare- up of eczema, and it is highly selective to the pathogen Staphylococcus aureus while being gentle to the skin microbiome, including beneficial bacteria such as Roseomonas mucosa and Corynebacterium tuberculostearicum. The compound was incorporated into cellulose-based fabrics such as rayon and cotton to create a controlled-release wet wrap/bandage which will be tested on mouse models of eczema. The technology has the potential become a standard of care for treating eczema patients and decrease or eliminate the use of steroid ointments in controlling atopic dermatitis in children and adult populations.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $970,285 )
2025	2025	CFD RESEARCH CORPORATION	6820 MOQUIN DR NW	HUNTSVILLE	AL	35806	MADISON	USA	Research and Training in Complementary and Integrative Health	001	3	8/8/2025	NON-COMPETING CONTINUATION	$920,285
2025	2025	CFD RESEARCH CORPORATION	6820 MOQUIN DR NW	HUNTSVILLE	AL	35806	MADISON	USA	Research and Training in Complementary and Integrative Health	000	2	8/7/2025	SUPPLEMENT FOR EXPANSION	$50,000
														Subtotal = $970,285

Issue Date FY: 2024 ( Subtotal = $656,274 )
2024	2024	CFD RESEARCH CORPORATION	6820 MOQUIN DR NW	HUNTSVILLE	AL	35806	MADISON	USA	Research and Training in Complementary and Integrative Health	000	2	9/20/2024	COMPETING CONTINUATION	$656,274
														Subtotal = $656,274

Grand Total All Awards = $1,626,559

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Controlled Release Eczema Bandage (CREB)

Award Number: R44AT011486

ORGANIZATION: CENTER FOR DRUG EVALUATION AND RESEARCH, NIH

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 08/01/2021

PERIOD OF PERFORMANCE END DATE: 08/31/2026

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