Saturday, January 10, 2026 1/10/2026

Spatial single cell analysis of the human Alzheimer's Disease brain

Award Number: R44AG085832
ORGANIZATION: NATIONAL INSTITUTE ON AGING
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 09/21/2023
PERIOD OF PERFORMANCE END DATE: 09/30/2025

Group Awards By:

View Award Description

Spatial single cell analysis of the human Alzheimer's Disease brain - SUMMARY The major goal of this project is to study human Alzheimer’s Disease (AD) brains using the Spatial Genomics GenePS instrument for automated large scale gene expression analysis at single cell resolution. At Spatial Genomics, we are commercializing the sequential fluorescence in situ hybridization (seqFISH) technology (Eng et al, 2019) that allows thousands of genes to be imaged directly in brain samples. We have experience working with human brains with our seqFISH technology and will hone the technology for use in human brains. Using the seqFISH method, we will identify changes in cell types, spatial organization of groups of cells, and signaling interactions between neighboring cells in the human AD brain.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $0 )
2025	2024	SPATIAL GENOMICS, INC.	145 VISTA AVE STE 111	PASADENA	CA	91107	LOS ANGELES	USA	Aging Research	000	2	4/30/2025	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2024 ( Subtotal = $1,229,313 )
2024	2024	SPATIAL GENOMICS, INC.	145 VISTA AVE STE 111	PASADENA	CA	91107	LOS ANGELES	USA	Aging Research	000	2	7/9/2024	NON-COMPETING CONTINUATION	$1,229,313
														Subtotal = $1,229,313

Issue Date FY: 2023 ( Subtotal = $1,229,313 )
2023	2023	SPATIAL GENOMICS, INC.	145 VISTA AVE STE 111	PASADENA	CA	91107	LOS ANGELES	USA	Aging Research	000	1	9/20/2023	NEW	$1,229,313
														Subtotal = $1,229,313

Grand Total All Awards = $2,458,626

Top

All Categories

About

Search

Reports

Data Submission

Award Information

Spatial single cell analysis of the human Alzheimer's Disease brain

Award Number: R44AG085832

ORGANIZATION: NATIONAL INSTITUTE ON AGING

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 09/21/2023

PERIOD OF PERFORMANCE END DATE: 09/30/2025

Federal Websites

Department of Health & Human Services

HHS Operating Divisions

HHS Staff Divisions

Download A Document Viewer