Monday, December 15, 2025 12/15/2025

NOISE-ISOLATING CAPSULE FOR SMALL-ANIMAL FMRI RESEARCH

Award Number: R43MH075466
ORGANIZATION: NATIONAL INSTITUTE OF MENTAL HEALTH
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 09/12/2005
PERIOD OF PERFORMANCE END DATE: 03/11/2006

Group Awards By:

View Award Description

NOISE-ISOLATING CAPSULE FOR SMALL-ANIMAL FMRI RESEARCH - DESCRIPTION (provided by applicant): The project's long-term objective is to provide a capsule that will permit functional magnetic resonance imaging (fMRI) to be carried out on test animals conveniently without subjecting these animals to the stresses associated with the acoustic noise produced by MRI equipment. Such a capsule will facilitate imaging research on animal models to identify brain changes associated with the use and abuse of psychoactive substances, since acoustic noise stress interacts with the effects of these substances. A proof-of-principle capsule of a clear plastic will be built to accommodate a small primate and fit into a typical MRI system. Acoustical measurement equipment that can operate reliably in a MRI scanner's intense magnetic fields will be obtained and its performance will be verified. The intial capsule will be provided with various acoustic barrier arrangements consisting of double-wall structures and resilient layers topped by massive layers, with acoustically absorptive layers added on the exterior. The noise isolating performance of these barrier arrangements will be measured, modeled analytically, and optimized -- both for conventional scanning and for scanning protocols that generate acoustic noise in only limited frequency ranges. Detailed design of two prototype capsules with high acoustic attenuation will be carried out. The design will take account of non-acoustical requirements, such as the need to observe the test subject, the need to clean and disinfect the capsule, and accommodation of animals of slightly different sizes. An initial study aimed at enhancing the capsule's noise isolation performance by active control means will be performed. This study will address sensor and actuator locations and types, the transfer functions between these, and the control logic.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2005 ( Subtotal = $98,477 )
2005	2005	ACENTECH INC	33 MOULTON STREET	CAMBRIDGE	MA	02138	MIDDLESEX	USA	Mental Health Research Grants	000	1	9/9/2005	NEW	$98,477
														Subtotal = $98,477

Grand Total All Awards = $98,477

Top

All Categories

About

Search

Reports

Data Submission

Award Information

NOISE-ISOLATING CAPSULE FOR SMALL-ANIMAL FMRI RESEARCH

Award Number: R43MH075466

ORGANIZATION: NATIONAL INSTITUTE OF MENTAL HEALTH

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 09/12/2005

PERIOD OF PERFORMANCE END DATE: 03/11/2006

Federal Websites

Department of Health & Human Services

HHS Operating Divisions

HHS Staff Divisions

Download A Document Viewer