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Reducing PFAS Exposure Through In-situ Microbial Remediation of PFAS Impacted Matrixes

Award Number: R43ES037574
ORGANIZATION: NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 07/18/2025
PERIOD OF PERFORMANCE END DATE: 06/30/2026

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Reducing PFAS Exposure Through In-situ Microbial Remediation of PFAS Impacted Matrixes - Project Summary Ongoing and legacy use of highly persistent per- and polyfluoroalkyl substances (PFAS) has led to widespread environmental contamination across the US. Emerging insight into the adverse health impacts of PFAS exposure has resulted in intense scrutiny of PFAS contamination, stringent environmental regulations, and massive liability. PFAS in food and drinking water are major sources of human PFAS exposure. Food products from PFAS-impacted agricultural land can contain PFAS concentrations that are hazardous to human health. Nationally, an estimated 20 million acres of agricultural land are impacted with PFAS, mainly due to applications of PFAS-impacted biosolid fertilizer and the use of irrigation sources contaminated with PFAS. Discharge from industrial activity and the use of firefighting products containing aqueous film-forming foam (AFFF) can also directly contaminate soil. Impacted soils can leach PFAS into drinking water sources, further harming human health. While several physical and/or chemical methods have shown promise for destruction of PFAS in soil, the feasibility of scaling these technologies is uncertain due to high cost, high energy use, and/or the use of hazardous chemicals for PFAS extraction and destruction. Current approaches for remediation of soil include PFAS stabilization and soil removal. Neither of these existing approaches permanently destroy PFAS, creating the potential for further harm to human health. Microbial-mediated bioremediation represents a scalable, cost-effective in situ alternative to current remediation approaches. BluumBio has identified two soil microbes which rapidly degrade diverse PFAS, including the six PFAS currently regulated by the US Environmental Protection Agency. This project seeks to develop a product formulation which supports optimal viability of both PFAS degrading microbes in soil environments. Our final powdered product formulation will contain dried PFAS-degrading microbes with nutrients necessary for microbial viability and bioactivity and will be mixed with water for applications on soil. We will characterize in situ PFAS degradation resulting from applications of microbial product formulations on PFAS-impacted soil samples in laboratory treatability studies. Following microbial-mediated PFAS degradation, we will characterize fluorinated breakdown products resulting from biodegradation. Our laboratory treatability studies will inform product application guidelines towards future large scale field trials. Our project will produce a scalable, microbial based solution for in situ remediation of PFAS-impacted soils. BluumBio’s novel PFAS bioremediation solution will reduce exposure to PFAS and directly improve human health.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $188,466 )
2025	2025	BLUUMBIO INC	1133 EVELYN AVE	ALBANY	CA	94706	ALAMEDA	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	000	1	7/17/2025	NEW	$188,466
														Subtotal = $188,466

Grand Total All Awards = $188,466

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Reducing PFAS Exposure Through In-situ Microbial Remediation of PFAS Impacted Matrixes

Award Number: R43ES037574

ORGANIZATION: NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 07/18/2025

PERIOD OF PERFORMANCE END DATE: 06/30/2026

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