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AST: On Target Cards for Monitoring Superfund Sites

Award Number: R43ES031906
ORGANIZATION: NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 05/01/2020
PERIOD OF PERFORMANCE END DATE: 10/31/2022

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AST: On Target Cards for Monitoring Superfund Sites - Project Summary Superfund sites pose a significant risk to human health for those living nearby as they have high levels of toxic chemicals that can impact the local water and soil chemistry, leading to a myriad of diseases including kidney disease, cancer, and heart disease. Currently the Superfund site list consists of ~1400 active or proposed sites in the United States. There is an on-going need to measure remediation effectiveness and monitor toxic chemical levels over time to minimize the risk to surrounding populations. Heavy metals are common toxic chemicals found in Superfund sites. Traditional laboratory methods are capable of measuring metals but are subject to long lead times (often weeks) as well as high instrumentation and labor costs. As a result, measurements are performed infrequently and can result in unanticipated releases, putting surrounding communities at risk. Because of these problems, several point-of-need measurement technologies are used to measure heavy metals at Superfund sites, including X-Ray Fluorescence (XRF) and colorimetric test kits, but both approaches have significant limitations. The field, and Superfund sites in particular, lack simple sensors that can measure multiple toxic metals simultaneously with minimal user steps and at relevant concentration levels. The goal of this project is to develop a multiplexed water quality monitoring system for measuring toxic metals in ground and surface water at Superfund sites using Access Sensor Technology's On-Target® card system. On-Target® cards quickly and easily measure metal concentrations in water using proprietary colorimetric reactions that generate a colored circle with a diameter proportional to concentration. While we have made significant progress with this technology, it is not applicable to Superfund site monitoring today because current detection limits are too high (ppm versus ppb) and the cards only detect a single metal, meaning users must carry a large number cards with them for complete profiling. During Phase I, we will focus on reducing the detection limits (Aim 1), creating the multiplexed assay (Aim 2), and developing first generation data visualization software while performing initial field studies (Aim 3). Samples from the Lincoln Park site (abandoned Uranium milling site) in Fremont County, Colorado will be used for testing. Our sensing system will be validated against ICP-MS or AAS for rigor. At the end of Phase I, we will have successfully created a prototype second-generation On-Target® product that enables multiplexed metal analysis at concentration levels relevant to our customers. The effort will position us for both further development during Phase II with additional analytes and penetration into the market through connections with early adopters.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2023 ( Subtotal = -$14,152 )
2023	2020	ACCESS SENSOR TECHNOLOGIES LLC	320 E VINE DR	FORT COLLINS	CO	80524	LARIMER	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	000	1	4/13/2023	NEW	-$14,152
														Subtotal = -$14,152

Issue Date FY: 2022 ( Subtotal = $0 )
2022	2020	ACCESS SENSOR TECHNOLOGIES LLC	320 E VINE DR STE 221	FORT COLLINS	CO	80524	LARIMER	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	000	1	2/9/2022	NEW	$0
														Subtotal = $0

Issue Date FY: 2020 ( Subtotal = $172,279 )
2020	2020	ACCESS SENSOR TECHNOLOGIES LLC	2401 RESEARCH BLVD. STE 107	FORT COLLINS	CO	80526	LARIMER	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	000	1	4/16/2020	NEW	$172,279
														Subtotal = $172,279

Grand Total All Awards = $158,127

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AST: On Target Cards for Monitoring Superfund Sites

Award Number: R43ES031906

ORGANIZATION: NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 05/01/2020

PERIOD OF PERFORMANCE END DATE: 10/31/2022

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