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Development of a Low-Profile Dual Hormone Patch Pump with Novel Occlusion Sensor

Award Number: R43DK110972
ORGANIZATION: NATIONAL INSTITUTE OF DIABETES & DIGESTIVE & KIDNEY DISEASES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 09/01/2016
PERIOD OF PERFORMANCE END DATE: 08/31/2018

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Development of a Low-Profile Dual Hormone Patch Pump with Novel Occlusion Sensor - Development of a Low-Profile Dual Hormone Patch Pump with Novel Occlusion Sensor Project Summary: The Specific Aim of this project is to develop a discrete, low-profile, dual hormone drug delivery system using SFC Fluidics’ enabling microfluidic technologies. A dual ePump® will be developed in which a single ePump body will independently and accurately deliver both insulin and glucagon from two separate reservoirs. Latching micro-valve sets will independently and safely control the delivery of each hormone and a flow confirmation sensor will identify dosing errors from either occlusions or electrical/mechanical failures. Phase I will see the development of an early prototype with control system, and a dosing accuracy of +/- 5% (for nL to µL dosing volumes) will be targeted. During Phase II, SFC Fluidics will work closely with clinicians and drug formulation, glucose sensor and control algorithm developers to develop a robust and reliable artificial pancreas.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2021 ( Subtotal = $0 )
2021	2016	SFC FLUIDICS, INC.	534 W RESEARCH CENTER BLVD	FAYETTEVILLE	AR	72701	WASHINGTON	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	1	9/7/2021	NEW	$0
														Subtotal = $0

Issue Date FY: 2017 ( Subtotal = $30,000 )
2017	2017	SFC FLUIDICS, INC.	534 W RESEARCH CENTER BLVD	FAYETTEVILLE	AR	72701	WASHINGTON	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	1	9/15/2017	SUPPLEMENT FOR EXPANSION	$30,000
														Subtotal = $30,000

Issue Date FY: 2016 ( Subtotal = $225,000 )
2016	2016	SFC FLUIDICS LLC	535 WEST RESEARCH CENTER BLVD	FAYETTEVILLE	AR	72701	WASHINGTON	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	1	8/30/2016	NEW	$225,000
														Subtotal = $225,000

Grand Total All Awards = $255,000

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Development of a Low-Profile Dual Hormone Patch Pump with Novel Occlusion Sensor

Award Number: R43DK110972

ORGANIZATION: NATIONAL INSTITUTE OF DIABETES & DIGESTIVE & KIDNEY DISEASES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 09/01/2016

PERIOD OF PERFORMANCE END DATE: 08/31/2018

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