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Removing implementation obstacles and tailoring reward-based technology programs to patient psychographic characteristics to sustainably increase adherence to substance use disorder pharmacotherapies

Award Number: R43DA049495
ORGANIZATION: NATIONAL INSTITUTE ON DRUG ABUSE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 07/01/2019
PERIOD OF PERFORMANCE END DATE: 12/31/2020

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Removing implementation obstacles and tailoring reward-based technology programs to patient psychographic characteristics to sustainably increase adherence to substance use disorder pharmacotherapies - Project Summary The objectives of this proposal are to facilitate the implementation of loyalty/reward-based programs to increase adherence to medical treatment among patients with substance use disorders through innovative solutions to three challenges. One challenge is that increasingly complicated federal regulations dissuade many hospitals and clinics from implementing loyalty/reward-based programs. Second, loyalty/rewards programs using only monetary incentives can be financially unsustainable. Third, the effectiveness of reward programs may vary based on individual patient characteristics. We propose to address these challenges by 1) Offering health centers educational resources related to regulatory compliance, a questionnaire to self-assess compliance, and an online forum to share experiences; 2) Developing a reward library containing a taxonomy of types, schedules, and formats of monetary and non-monetary rewards used in prior studies and the associated behavior changes they have produced; 3) Systematically review the research literature on the effectiveness of various forms of rewards for patients based on their demographic and psychographic traits. Building on our team’s experience developing software to promote patient appointment attendance, in Phase I a new tool will be created and tested with a sample of ten providers and ten patients who are prescribed but not fully adherent to substance use disorder treatment. These participants will be recruited through our network of university, pharmacy and primary care partners. Patients will receive tailored text messages (in English or Spanish) encouraging adherence, self-report their treatment adherence (which will be verified through smart pill caps and biological testing), earn points for adherence that can be exchanged for rewards customized for them based on a baseline survey, and report their satisfaction with the program and process at the end of the four-week study. This pilot will assess the feasibility and perceived usefulness of the product. If the pilot is successful, a Phase II study will be proposed to use an experimental medicine approach to evaluate the product’s efficacy at increasing adherence to treatment and the mechanisms through which the rewards program works using a Multiphase Optimization Strategy and randomized controlled trial.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2021 ( Subtotal = $0 )
2021	2019	TRANSCENDENT INTERNATIONAL, LLC	405 LEXINGTON AVE FL 9	NEW YORK	NY	10174	NEW YORK	USA	Drug Use and Addiction Research Programs	000	1	4/19/2021	NEW	$0
														Subtotal = $0

Issue Date FY: 2020 ( Subtotal = $0 )
2020	2019	TRANSCENDENT INTERNATIONAL, LLC	205 E 42ND ST FL 20	NEW YORK	NY	10017	NEW YORK	USA	Drug Use and Addiction Research Programs	000	1	1/7/2020	NEW	$0
														Subtotal = $0

Issue Date FY: 2019 ( Subtotal = $223,676 )
2019	2019	TRANSCENDENT INTERNATIONAL, LLC	205 E 42ND ST FL 20	NEW YORK	NY	10017	NEW YORK	USA	Drug Use and Addiction Research Programs	000	1	6/26/2019	NEW	$223,676
														Subtotal = $223,676

Grand Total All Awards = $223,676

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Removing implementation obstacles and tailoring reward-based technology programs to patient psychographic characteristics to sustainably increase adherence to substance use disorder pharmacotherapies

Award Number: R43DA049495

ORGANIZATION: NATIONAL INSTITUTE ON DRUG ABUSE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 07/01/2019

PERIOD OF PERFORMANCE END DATE: 12/31/2020

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