Official websites use .gov

A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS

A lock ( 🔒 ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

Need Help

mHealth app for caregiver instruction in manual therapy for chemotherapy-induced peripheral neuropathy

Award Number: R43CA268678
ORGANIZATION: NATIONAL CANCER INSTITUTE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 08/18/2022
PERIOD OF PERFORMANCE END DATE: 07/31/2023

Group Awards By:

View Award Description

mHealth app for caregiver instruction in manual therapy for chemotherapy-induced peripheral neuropathy - Chemotherapy can damage nervous system structures leading to chemotherapy-induced peripheral neuropathy (CIPN) which impairs quality of life and daily functioning for millions of cancer survivors. Some 30% of recipients live with CIPN chronically beyond completion of chemotherapy. Conventional care is symptomatic including antidepressants, anticonvulsants, analgesics, vitamin supplements and topical gels to manage symptoms. While there are no FDA-approved treatments, evidence indicates that specific manual therapy techniques can reduce symptoms of CIPN. There is also evidence that caregivers can learn safe and effective manual therapy techniques for use in caregiving through multimedia instruction. However, there currently is no caregiver education product teaching specific techniques and safety precautions pertaining to CIPN. This project will develop a mobile health (mHealth) app to empower caregivers with knowledge, skills, self-efficacy and motivation to support loved ones with CIPN by use of simple manual techniques based on specific understanding and safety precautions for CIPN. The project will use a human-centered design approach in formative research to develop a “minimum viable product (MVP)” for the eventual caregiver mHealth app. A user-centered, iterative process with caregiver focus groups will guide development of the MVP which will then be assessed for feasibility through a Think-Aloud protocol. Specific Aims are as follows: Aim 1. Develop initial user-centered app design. We will develop preliminary requirements for core educational content to be featured in the app, then refine this with patient focus group feedback. The resulting initial app design will incorporate principles of ease of navigation, usability, utility, and engagement. Aim 2. Refine app design through an iterative process of qualitative feedback. The initial app design will be processed and revised through three rounds of caregiver focus groups for qualitative feedback and refinement. Qualitative analysis of responses after each round will be conducted, and applied to produce revised versions through round 3, resulting in the MVP prototype. Aim 3. Evaluate usability of a minimum viable product (MVP). Caregivers will experience the MVP prototype through an interactive Think-Aloud session with the design team that is recorded for qualitative analysis. This will be followed by debriefing with structured interview questions about design, relevance and intent to use. Quantitative data will assess system usability, and perceived relevance and impact on caregiving. Feasibility criteria will be usability scores and user ratings of perceived value and “intent to use” in caregiving. If Phase I is successful the app will be completed in Phase II followed by a large RCT to assess outcomes of use for both CIPN sufferers and caregivers. Eventual public health benefits include improved quality of life and functional well-being for the population of CIPN sufferers, reduced caregiver burden, and reduced economic burden from medical costs and lost productivity associated with CIPN.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2024 ( Subtotal = $0 )
2024	2022	COLLINGE AND ASSOCIATES, INC.	3480 KINCAID ST	EUGENE	OR	97405	LANE	USA	Cancer Cause and Prevention Research	000	1	3/4/2024	NEW	$0
														Subtotal = $0

Issue Date FY: 2022 ( Subtotal = $399,085 )
2022	2022	COLLINGE AND ASSOCIATES, INC.	3480 KINCAID ST	EUGENE	OR	97405	LANE	USA	Cancer Cause and Prevention Research	000	1	8/18/2022	NEW	$399,085
														Subtotal = $399,085

Grand Total All Awards = $399,085

Top

All Categories

About

Search

Reports

Data Submission

Award Information

mHealth app for caregiver instruction in manual therapy for chemotherapy-induced peripheral neuropathy

Award Number: R43CA268678

ORGANIZATION: NATIONAL CANCER INSTITUTE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 08/18/2022

PERIOD OF PERFORMANCE END DATE: 07/31/2023

Federal Websites

Department of Health & Human Services

HHS Operating Divisions

HHS Staff Divisions

Download A Document Viewer