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Development of Reagents for Sequencing Proteins and Protein Fragments on a Next-Generation DNA Sequencer

Award Number: R43CA203629
ORGANIZATION: NATIONAL CANCER INSTITUTE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 09/05/2016
PERIOD OF PERFORMANCE END DATE: 04/30/2018

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Development of Reagents for Sequencing Proteins and Protein Fragments on a Next-Generation DNA Sequencer - ¿ DESCRIPTION (provided by applicant) Proteomics is the study of the structure and function of proteins in biological systems. It has a wide range of applications starting from protein expression profiling in healthy versus diseased states of an organism to analyzing the interaction of proteins in living organisms to mapping of protein modifications and identification of how, when, and where proteins are modified within a living cell. We are developing an approach for the large-scale, massively parallel digital counting of proteins and peptide sequencing based on single molecule detection and a microfluidic platform technology. This revolutionary protein measurement platform will significantly reduce the amount of sample required for analysis and allow identification of low abundance proteins without bias. This innovation will have far-reaching impacts on quantitative systems biology, disease biomarker discovery and validation, clinical diagnostics, and personalized medicine. Pharmaceutical-, reagent supply- and instrumentation companies have paid substantial premiums to acquire technologies that promise to more quickly and efficiently identify targets for both therapeutics and diagnostics. We expect successful release of the proposed instrument will generate substantial revenue in an already growing marketplace.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2018 ( Subtotal = $0 )
2018	2016	ENCODIA, INC	11125 FLINTKOTE AVE STE B	SAN DIEGO	CA	92121	SAN DIEGO	USA	Cancer Biology Research	000	1	9/11/2018	NEW	$0
														Subtotal = $0

Issue Date FY: 2016 ( Subtotal = $211,400 )
2016	2016	PROCURE LIFE SCIENCES, INC	9600 GUDELSKY DR BLDG 1A STE 115	ROCKVILLE	MD	20850	MONTGOMERY	USA	Cancer Biology Research	000	1	9/5/2016	NEW	$211,400
														Subtotal = $211,400

Grand Total All Awards = $211,400

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Development of Reagents for Sequencing Proteins and Protein Fragments on a Next-Generation DNA Sequencer

Award Number: R43CA203629

ORGANIZATION: NATIONAL CANCER INSTITUTE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 09/05/2016

PERIOD OF PERFORMANCE END DATE: 04/30/2018

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