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Microbiome-Balancing Wraps for Managing Eczema

Award Number: R43AT011486
ORGANIZATION: CENTER FOR DRUG EVALUATION AND RESEARCH, NIH
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 08/01/2021
PERIOD OF PERFORMANCE END DATE: 04/30/2023

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Microbiome-Balancing Wraps for Managing Eczema - Project Summary/Abstract: The long-term goal of this project is to develop microbiome-balancing antimicrobial wraps to use in the treatment of atopic dermatitis or eczema infections. The topical steroids used in the treatment of atopic dermatitis cause many side-effects and addiction. Additionally, the antibiotics used to treat AD infections eliminate skin commensals along with the targeted pathogens, resulting in skin microbial imbalance. Skin commensals play an important role in preventing the re-colonization and re- occurrence of the eczema by inhibiting the pathogens. Protective wraps or wet wraps made of skin commensal gentle antimicrobial compounds can prevent atopic dermatitis by promoting the growth of skin beneficial microbes and inhibiting the skin pathogens. CFD Research has discovered novel natural product-based compounds with skin commensal gentle targeted antimicrobial activity. In this proposal we seek to develop skin microbiome-gentle antimicrobial cotton fabrics that can release the compound at a certain rate to inhibit the pathogens while promoting growth of skin commensals.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2024 ( Subtotal = $0 )
2024	2021	CFD RESEARCH CORPORATION	6820 MOQUIN DR NW	HUNTSVILLE	AL	35806	MADISON	USA	Research and Training in Complementary and Integrative Health	000	1	1/11/2024	NEW	$0
														Subtotal = $0

Issue Date FY: 2021 ( Subtotal = $253,024 )
2021	2021	CFD RESEARCH CORPORATION	6820 MOQUIN DR NW	HUNTSVILLE	AL	35806	MADISON	USA	Research and Training in Complementary and Integrative Health	000	1	7/28/2021	NEW	$253,024
														Subtotal = $253,024

Grand Total All Awards = $253,024

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Microbiome-Balancing Wraps for Managing Eczema

Award Number: R43AT011486

ORGANIZATION: CENTER FOR DRUG EVALUATION AND RESEARCH, NIH

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 08/01/2021

PERIOD OF PERFORMANCE END DATE: 04/30/2023

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