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A Gait and Path Tortuosity System for Monitoring Cognitive Decline from Daily Functions in Individuals with Alzheimer's Disease and/or Alzheimer's Disease Related Dementias (AD/ADRD)

Award Number: R43AG063679
ORGANIZATION: NATIONAL INSTITUTE ON AGING
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 04/01/2019
PERIOD OF PERFORMANCE END DATE: 03/31/2023

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A Gait and Path Tortuosity System for Monitoring Cognitive Decline from Daily Functions in Individuals with Alzheimer's Disease and/or Alzheimer's Disease Related Dementias (AD/ADRD) - Project Summary/Abstract Proposed is a sensing system that unobtrusively measures and reports gait properties which are correlated to accepted measures of cognitive decline. Significance: It is estimated that as of 2018 over 5.7 million Americans are afflicted with AD. Due to the aging demographics, this number is projected to double by 2050 at an estimated annual direct cost of $1.1 trillion. Measures of cognitive decline can help to inform family members, caregivers, and health-care providers about the functional status and needs of independent-living older individuals. The need to improve the assessment of cognitive changes affecting daily functions has been identified by the NIH and National Academy of Medicine (NAM). Many ADLs such as shopping, housecleaning, and bathing are difficult to objectively measure. Measuring these ADLs is generally manually intensive often requiring direct supervision by a caregiver. The changing demographics of the elderly mean now more elderly adults will no longer have the frequent interaction with caregivers required to accurately make these measures. Hypothesis: A system capable of measuring and reporting gait parameters which are correlated to accepted measures of cognitive decline can decrease caregivers' burden and increase quality of life for individuals with AD. Specific Aims: To prove the feasibility of the proposed system in Phase I IDL will 1) Generate user- centric requirements through focus group discussions; 2) Develop prototype system electronics and mechanical packaging; 3) Perform laboratory study of prototype functionality; and 4) Evaluate prototype performance through pilot human study. The overall Phase I effort will demonstrate the ability of the proposed system to accurately measure requisite gait measures and demonstrate the usability of the system by the target population.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2024 ( Subtotal = -$5,486 )
2024	2019	INNOVATIVE DESIGN LABS INC	861 E HENNEPIN AVE STE 450	MINNEAPOLIS	MN	55414	HENNEPIN	USA	Aging Research	000	1	12/7/2023	NEW	-$5,486
														Subtotal = -$5,486

Issue Date FY: 2022 ( Subtotal = $0 )
2022	2019	INNOVATIVE DESIGN LABS INC.	861 E HENNEPIN AVE STE 450	MINNEAPOLIS	MN	55414	HENNEPIN	USA	Aging Research	000	1	5/20/2022	NEW	$0
														Subtotal = $0

Issue Date FY: 2021 ( Subtotal = $0 )
2021	2019	INNOVATIVE DESIGN LABS INC.	861 E HENNEPIN AVE STE 450	MINNEAPOLIS	MN	55414	HENNEPIN	USA	Aging Research	000	1	4/7/2021	NEW	$0
														Subtotal = $0

Issue Date FY: 2019 ( Subtotal = $349,991 )
2019	2019	INNOVATIVE DESIGN LABS INC.	861 E HENNEPIN AVE STE 450	MINNEAPOLIS	MN	55414	HENNEPIN	USA	Aging Research	000	1	3/22/2019	NEW	$349,991
														Subtotal = $349,991

Grand Total All Awards = $344,505

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A Gait and Path Tortuosity System for Monitoring Cognitive Decline from Daily Functions in Individuals with Alzheimer's Disease and/or Alzheimer's Disease Related Dementias (AD/ADRD)

Award Number: R43AG063679

ORGANIZATION: NATIONAL INSTITUTE ON AGING

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 04/01/2019

PERIOD OF PERFORMANCE END DATE: 03/31/2023

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