Friday, July 4, 2025 7/4/2025

AUTOMATED DELINEATION, PARCELLATION AND ANALYSIS OF THE CEREBELLUM FROM MR IMAGES

Award Number: R43AA021945
ORGANIZATION: NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 06/01/2012
PERIOD OF PERFORMANCE END DATE: 05/31/2014

Group Awards By:

View Award Description

AUTOMATED DELINEATION, PARCELLATION AND ANALYSIS OF THE CEREBELLUM FROM MR IMAGES - DESCRIPTION (provided by applicant): Cerebellar involvement has been implicated in a large spectrum of disorders. Reduced cerebellar volumes have been reported in alcoholism, autism spectrum disorders, schizophrenia, mood disorders, and essential head tremors. As an example of the work demonstrating the more widespread role of the cerebellum in brain function, Sullivan and colleagues have demonstrated impairment in static upright balance with excessive sway in individuals with pathology of the anterior superior vermis, and have shown that alterations in nodes of the frontocerebellar circuitry can predict executive dysfunction in prefrontal regions. There has been an explosion of studies in the last decade examining functional brain networks using task-activated fMRI, and resting state functional connectivity MRI . For the most part, cerebellar morphometric studies and studies of the cerebellar components of brain networks have been ignored, largely as a consequence of lack of tools to support such investigations. The time is ripe for reliable and valid tools to support such studies. We believe that a cerebellar analysis toolkit (CATK) not only has a waiting audience and market, but its availability will act as a catalyst for the incorporation of the cerebellum in studies of brain structure and function, and thus will be of great significance. ! The goal of this SBIR project is to develop an integrated cerebellar segmentation / parcellation and analysis suite. The core component will be MR image delineation of the cerebellum and its subregions. The suite will include a comprehensive set of image and surface analysis tools, including the capability for shape analysis of cerebellar structures, and for visualization and surface editing. We will develop an integrated analysis environment with high performance tools implementation on GPUs using CUDA. CATK will have three major components: 1) cerebellar delineation, 2) A CUDA-based surface and image processing toolbox, and 3) A CUDA/openGL based rendering/surface editing tool. The product will provide a low cost means for extracting valuable information from existing MR image databases as well as from new data.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2013 ( Subtotal = $113,651 )
2013	2013	NEUROBEHAVIORAL RESEARCH, INC	201 Tamal Vista Blvd # 200	Corte Madera	CA	94925	MARIN	USA	Alcohol Research Programs	000	2	6/4/2013	NON-COMPETING CONTINUATION	$113,651
														Subtotal = $113,651

Issue Date FY: 2012 ( Subtotal = $134,999 )
2012	2012	NEUROBEHAVIORAL RESEARCH, INC	201 Tamal Vista Blvd # 200	Corte Madera	CA	94925	MARIN	USA	Alcohol Research Programs	000	1	5/24/2012	NEW	$134,999
														Subtotal = $134,999

Grand Total All Awards = $248,650

Top

All Categories

About

Search

Reports

Data Submission

Award Information

AUTOMATED DELINEATION, PARCELLATION AND ANALYSIS OF THE CEREBELLUM FROM MR IMAGES

Award Number: R43AA021945

ORGANIZATION: NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 06/01/2012

PERIOD OF PERFORMANCE END DATE: 05/31/2014

Federal Websites

Department of Health & Human Services

HHS Operating Divisions

HHS Staff Divisions

Download A Document Viewer