Friday, July 4, 2025 7/4/2025

PREVENTING CHOROIDAL NEOVASCULARIZATION BY LONG-TERM TRANSSCLERAL DRUG DELIVERY

Award Number: R41EY017473
ORGANIZATION: NATIONAL EYE INSTITUTE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: HEALTH SERVICES
PERIOD OF PERFORMANCE START DATE: 05/01/2006
PERIOD OF PERFORMANCE END DATE: 04/30/2007

Group Awards By:

View Award Description

PREVENTING CHOROIDAL NEOVASCULARIZATION BY LONG-TERM TRANSSCLERAL DRUG DELIVERY - DESCRIPTION (provided by applicant): Age-related Macular Degeneration (ARMD) is the leading cause of blindness for individuals over fifty-five years of age that live in the industrialized world. With the introduction of novel anti-angiogenic agents, clinical intervention is currently possible, but only for the wet form of the disease. However, these treatments are severely limited by the fact that they must be directly injected into the eye. This procedure carries a significant risk of complication and generates understandable issues of patient acceptability. There is a clear need for a therapy that either bypasses the need for ocular injection or reduces its frequency. Transscleral drug delivery provides a convenient way for delivering drug to the posterior segment of the eye. We propose to test and develop a novel and powerful transscleral drug delivery system that holds promise for being non-toxic, minimally invasive and highly customizable towards different therapies. The success of this proposal will offer a new method to the pharmaceutical industry and to patients worldwide to treat ARMD without the current burden of monthly or 6-weekly intraocular injections. For proof-of-concept, we will use a novel, human protein-based therapy that has shown great potential in preliminary animal studies.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2006 ( Subtotal = $293,017 )
2006	2006	POTENTIA PHARMACEUTICALS	1434 GODDARD AVENUE	LOUISVILLE	KY	40204	JEFFERSON	USA	Vision Research	000	1	5/1/2006	NEW	$293,017
														Subtotal = $293,017

Grand Total All Awards = $293,017

Top

All Categories

About

Search

Reports

Data Submission

Award Information

PREVENTING CHOROIDAL NEOVASCULARIZATION BY LONG-TERM TRANSSCLERAL DRUG DELIVERY

Award Number: R41EY017473

ORGANIZATION: NATIONAL EYE INSTITUTE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: HEALTH SERVICES

PERIOD OF PERFORMANCE START DATE: 05/01/2006

PERIOD OF PERFORMANCE END DATE: 04/30/2007

Federal Websites

Department of Health & Human Services

HHS Operating Divisions

HHS Staff Divisions

Download A Document Viewer